| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Benproperine (phosphate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | 0.119826 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0873178 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0651164 |
| SMAD3 | SMAD family member 3 | 0.0545187 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0490136 |
| RPL31 | ribosomal protein L31 | 0.0489899 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0488028 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0463265 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0443136 |
| RPL37A | ribosomal protein L37a | 0.0423931 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0412773 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0409418 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0382367 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0369537 |
| RPL35A | ribosomal protein L35a | 0.0365732 |
| AGR2 | anterior gradient 2 | 0.035481 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0345839 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0338723 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0336294 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0325101 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.031906 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0308441 |
| RPL13A | ribosomal protein L13a | 0.0304357 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0304342 |
| CTBP2 | C-terminal binding protein 2 | 0.0301055 |
| MCL1 | myeloid cell leukemia 1 | 0.0297139 |
| RPS23 | ribosomal protein S23 | 0.0282276 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0280042 |
| RPS25 | ribosomal protein S25 | 0.0275704 |
| ASPH | aspartate beta-hydroxylase | 0.0273021 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0269729 |
| RPL38 | ribosomal protein L38 | 0.0263573 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0260839 |
| FBXO11 | F-box protein 11 | 0.0259557 |
| ATXN1 | ataxin 1 | 0.0253663 |
| EGFR | epidermal growth factor receptor | 0.024807 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0245833 |
| PDE10A | phosphodiesterase 10A | 0.0245409 |
| RPS12 | ribosomal protein S12 | 0.0244045 |
| RPS27A | ribosomal protein S27a | 0.0243918 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0242281 |
| HM13 | histocompatibility (minor) 13 | 0.0237599 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0235356 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0233035 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0232156 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0230651 |
| RPS17 | ribosomal protein S17 | 0.0222777 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0217731 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0214167 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0212997 |
| RPS13 | ribosomal protein S13 | 0.0212196 |
| ACVR1 | activin A receptor, type I | 0.0208692 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0207317 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0207034 |
| FAM107B | family with sequence similarity 107, member B | 0.0206862 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0204371 |
| GOLGB1 | golgin B1 | 0.0203798 |
| AEBP2 | AE binding protein 2 | 0.0203062 |
| POF1B | premature ovarian failure, 1B | 0.0202785 |
| PGM3 | phosphoglucomutase 3 | 0.0199811 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0199631 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0193005 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0190472 |
| GPR75-ASB3 | GPR75-ASB3 readthrough | 0.0186843 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0186395 |
| FMNL2 | formin-like 2 | 0.0185072 |
| RPS8 | ribosomal protein S8 | 0.0184602 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0184312 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0182656 |
| DNHD1 | dynein heavy chain domain 1 | 0.018059 |
| RUNX1 | runt-related transcription factor 1 | 0.0179927 |
| MRTFA | myocardin related transcription factor A | 0.0178794 |
| RTN3 | reticulon 3 | 0.0177598 |
| SERTAD2 | SERTA domain containing 2 | 0.0176852 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0176301 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0174765 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0174464 |
| PTMA | prothymosin, alpha | 0.0173731 |
| MED13L | mediator complex subunit 13-like | 0.0172653 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0170975 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0170533 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0170447 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0169684 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0169495 |
| FOCAD | focadhesin | 0.0169423 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0168848 |
| PTGES2 | prostaglandin E synthase 2 | 0.0167231 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0166696 |
| UBAP2 | ubiquitin associated protein 2 | 0.0165504 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0165473 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0164949 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0164472 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0164451 |
| TLE4 | transducin-like enhancer of split 4 | 0.0164235 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0163866 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0162661 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0162505 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0161489 |
| RPS29 | ribosomal protein S29 | 0.0161308 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0160213 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.167751 |
| EZR | ezrin | -0.15737 |
| NDRG1 | N-myc downstream regulated 1 | -0.150489 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.111692 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.10978 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.106383 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0934499 |
| FTL | ferritin, light polypeptide | -0.0895158 |
| ANXA2 | annexin A2 | -0.0859142 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0831606 |
| LMO7 | LIM domain 7 | -0.0796358 |
| TXNRD1 | thioredoxin reductase 1 | -0.0747722 |
| POTEF | POTE ankyrin domain family, member F | -0.073495 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0708145 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0609151 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0603033 |
| LYZ | lysozyme | -0.0597436 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0594233 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0593103 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0556664 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0551575 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0526916 |
| RPL18 | ribosomal protein L18 | -0.0522471 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0500787 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0496951 |
| AHNAK | AHNAK nucleoprotein | -0.049366 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.048986 |
| KRT18 | keratin 18, type I | -0.0489622 |
| WASF2 | WAS protein family, member 2 | -0.0487225 |
| KLF6 | Kruppel-like factor 6 | -0.048672 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.0486566 |
| FBXO32 | F-box protein 32 | -0.0483501 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0474085 |
| JUP | junction plakoglobin | -0.0471043 |
| KRT20 | keratin 20, type I | -0.0468898 |
| ACTN4 | actinin, alpha 4 | -0.046528 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0458854 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0458013 |
| KRT19 | keratin 19, type I | -0.0448877 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0444526 |
| LDHA | lactate dehydrogenase A | -0.0439395 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0436494 |
| RPLP0 | ribosomal protein, large, P0 | -0.0430048 |
| S100A6 | S100 calcium binding protein A6 | -0.0429327 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0419126 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0418492 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0418139 |
| DSPP | dentin sialophosphoprotein | -0.0410416 |
| ETV6 | ets variant 6 | -0.0397851 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0397055 |
| EMP1 | epithelial membrane protein 1 | -0.0394671 |
| MYADM | myeloid-associated differentiation marker | -0.0394277 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0392096 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0390707 |
| RPL12 | ribosomal protein L12 | -0.0386102 |
| TPI1 | triosephosphate isomerase 1 | -0.0381598 |
| JUN | jun proto-oncogene | -0.0381352 |
| BCL2L1 | BCL2-like 1 | -0.0377514 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0376423 |
| MKI67 | marker of proliferation Ki-67 | -0.037537 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0373065 |
| CENPF | centromere protein F, 350/400kDa | -0.0369603 |
| LMNA | lamin A/C | -0.0364697 |
| PERP | PERP, TP53 apoptosis effector | -0.0364094 |
| STK24 | serine/threonine kinase 24 | -0.0363558 |
| TAGLN2 | transgelin 2 | -0.0359959 |
| BPTF | bromodomain PHD finger transcription factor | -0.035553 |
| TMC5 | transmembrane channel-like 5 | -0.0355299 |
| DNM2 | dynamin 2 | -0.034946 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0349054 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0348534 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0343434 |
| PGK1 | phosphoglycerate kinase 1 | -0.0342599 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.034257 |
| ACTG1 | actin gamma 1 | -0.0341671 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0340232 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0339207 |
| TJP1 | tight junction protein 1 | -0.0334776 |
| WWC1 | WW and C2 domain containing 1 | -0.0334365 |
| RPS19 | ribosomal protein S19 | -0.0334302 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0332594 |
| B2M | beta-2-microglobulin | -0.0331783 |
| TXNIP | thioredoxin interacting protein | -0.0331543 |
| LIPH | lipase, member H | -0.0327619 |
| NBEAL1 | neurobeachin-like 1 | -0.0327576 |
| HDLBP | high density lipoprotein binding protein | -0.0325297 |
| YBX3 | Y box binding protein 3 | -0.0323953 |
| RND3 | Rho family GTPase 3 | -0.032086 |
| ABHD2 | abhydrolase domain containing 2 | -0.0318862 |
| PTK2 | protein tyrosine kinase 2 | -0.0318589 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0317872 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0317426 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0317334 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0316549 |
| GPX2 | glutathione peroxidase 2 | -0.0313105 |
| TMEM45B | transmembrane protein 45B | -0.0309816 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0309489 |
| TMEM123 | transmembrane protein 123 | -0.0307629 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0305767 |
| RNF24 | ring finger protein 24 | -0.0304556 |
