| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.185396 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.103696 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0750299 |
| PLIN2 | perilipin 2 | 0.0416535 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.041217 |
| ATP13A3 | ATPase type 13A3 | 0.0400866 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0359495 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0333836 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0307312 |
| POTEF | POTE ankyrin domain family, member F | 0.0293353 |
| FOSL1 | FOS-like antigen 1 | 0.0272462 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0271786 |
| CCNL1 | cyclin L1 | 0.0269678 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0264648 |
| CENPF | centromere protein F, 350/400kDa | 0.0263435 |
| MSN | moesin | 0.0257884 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0249531 |
| FAM120A | family with sequence similarity 120A | 0.0248621 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0239578 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0232823 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0231993 |
| BBX | bobby sox homolog (Drosophila) | 0.0231553 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.02284 |
| PCBP2 | poly(rC) binding protein 2 | 0.0226627 |
| SUCO | SUN domain containing ossification factor | 0.0226049 |
| MMP12 | matrix metallopeptidase 12 | 0.0224356 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0220547 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0218229 |
| RANBP9 | RAN binding protein 9 | 0.0212492 |
| USP3 | ubiquitin specific peptidase 3 | 0.0211849 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0196309 |
| MED13L | mediator complex subunit 13-like | 0.0196138 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0192107 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | 0.0188942 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.018817 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0185985 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0185844 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0185493 |
| FAM168A | family with sequence similarity 168, member A | 0.0182904 |
| TFG | TRK-fused gene | 0.0182863 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0181586 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0180774 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0178206 |
| OLA1 | Obg-like ATPase 1 | 0.017584 |
| GJD3 | gap junction protein, delta 3, 31.9kDa | 0.0175105 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0174877 |
| PLK2 | polo-like kinase 2 | 0.0174665 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0174657 |
| STC2 | stanniocalcin 2 | 0.0173963 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.0171792 |
| FBXO42 | F-box protein 42 | 0.0169748 |
| TOX | thymocyte selection-associated high mobility group box | 0.016938 |
| TPX2 | TPX2, microtubule-associated | 0.0168708 |
| EGFR | epidermal growth factor receptor | 0.0168689 |
| USP47 | ubiquitin specific peptidase 47 | 0.016448 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0163877 |
| ARRDC3 | arrestin domain containing 3 | 0.016275 |
| PDS5B | PDS5 cohesin associated factor B | 0.0162508 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.015974 |
| SSRP1 | structure specific recognition protein 1 | 0.0159008 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.015872 |
| KIF23 | kinesin family member 23 | 0.0157289 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.015631 |
| RNF145 | ring finger protein 145 | 0.0154989 |
| ZNF292 | zinc finger protein 292 | 0.015464 |
| MEF2A | myocyte enhancer factor 2A | 0.0153446 |
| RAB6A | RAB6A, member RAS oncogene family | 0.015112 |
| MSI2 | musashi RNA-binding protein 2 | 0.0150762 |
| COL5A2 | collagen, type V, alpha 2 | 0.0150517 |
| RYBP | RING1 and YY1 binding protein | 0.0150409 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0149721 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0149497 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0147818 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0146912 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0145913 |
| CEP70 | centrosomal protein 70kDa | 0.0145322 |
| INSIG1 | insulin induced gene 1 | 0.0145233 |
| SETD5 | SET domain containing 5 | 0.0144074 |
| REST | RE1-silencing transcription factor | 0.0144007 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.0143359 |
| BRD2 | bromodomain containing 2 | 0.0141212 |
| VEGFA | vascular endothelial growth factor A | 0.0140414 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0139378 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0139278 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0138582 |
| CRY1 | cryptochrome circadian clock 1 | 0.0137886 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0137824 |
| LRRC58 | leucine rich repeat containing 58 | 0.0136237 |
| PCM1 | pericentriolar material 1 | 0.0136112 |
| EFHD2 | EF-hand domain family, member D2 | 0.0135902 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0135648 |
| SEPTIN9 | septin 9 | 0.0135555 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0135167 |
| PFN2 | profilin 2 | 0.013368 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.0133452 |
| VMP1 | vacuole membrane protein 1 | 0.0132206 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0131738 |
| SEPTIN11 | septin 11 | 0.0131537 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0131444 |
| RPL21 | ribosomal protein L21 | 0.0131274 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.283132 |
| EXT1 | exostosin glycosyltransferase 1 | -0.146723 |
| CD44 | CD44 molecule (Indian blood group) | -0.132328 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128056 |
| MT2A | metallothionein 2A | -0.105553 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0911187 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0850454 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.08118 |
| HLA-C | major histocompatibility complex, class I, C | -0.079243 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0789515 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0706402 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0679855 |
| ANXA2 | annexin A2 | -0.0659115 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0644838 |
| SMAD3 | SMAD family member 3 | -0.0622635 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0590733 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0582246 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0576982 |
| OSMR | oncostatin M receptor | -0.055775 |
| ACTG1 | actin gamma 1 | -0.0545608 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0536578 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0530908 |
| TMSB4X | thymosin beta 4, X-linked | -0.0527248 |
| AHNAK | AHNAK nucleoprotein | -0.052305 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0521615 |
| TXNRD1 | thioredoxin reductase 1 | -0.0518713 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0515713 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0514802 |
| FLNB | filamin B, beta | -0.0512719 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0503549 |
| TUBB | tubulin, beta class I | -0.0485184 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0480688 |
| RND3 | Rho family GTPase 3 | -0.047734 |
| HLA-A | major histocompatibility complex, class I, A | -0.0474529 |
| TMSB10 | thymosin beta 10 | -0.0473535 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0452955 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0451249 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0446931 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0435664 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0416018 |
| HLA-E | major histocompatibility complex, class I, E | -0.0405253 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0405233 |
| ASPH | aspartate beta-hydroxylase | -0.040273 |
| RPLP2 | ribosomal protein, large, P2 | -0.0400505 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.0398077 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0392462 |
| FLNA | filamin A, alpha | -0.0388118 |
| CANX | calnexin | -0.0387712 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0382654 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0381937 |
| GLIS3 | GLIS family zinc finger 3 | -0.0374131 |
| FSTL1 | follistatin-like 1 | -0.0372756 |
| CAVIN1 | caveolae associated protein 1 | -0.0371387 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0368063 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0358582 |
| LMNA | lamin A/C | -0.0358131 |
| ENO1 | enolase 1, (alpha) | -0.0357796 |
| GNAS | GNAS complex locus | -0.035677 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.035315 |
| IL6ST | interleukin 6 signal transducer | -0.0352999 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0352826 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.035195 |
| SQSTM1 | sequestosome 1 | -0.0344216 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0343275 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0342808 |
| RRBP1 | ribosome binding protein 1 | -0.0340277 |
| RPL26 | ribosomal protein L26 | -0.0334347 |
| ZNF432 | zinc finger protein 432 | -0.0333492 |
| DEK | DEK proto-oncogene | -0.033083 |
| RNF213 | ring finger protein 213 | -0.0329008 |
| NABP1 | nucleic acid binding protein 1 | -0.0326717 |
| COL5A1 | collagen, type V, alpha 1 | -0.0325173 |
| CLTC | clathrin, heavy chain (Hc) | -0.0324585 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0323451 |
| RAI14 | retinoic acid induced 14 | -0.032105 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0316363 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0310027 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0308548 |
| B2M | beta-2-microglobulin | -0.0298432 |
| ZXDC | ZXD family zinc finger C | -0.0297439 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0295407 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0293961 |
| RPS20 | ribosomal protein S20 | -0.0293492 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0290782 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0289579 |
| RPL35A | ribosomal protein L35a | -0.028939 |
| SDC4 | syndecan 4 | -0.0286074 |
| THBS1 | thrombospondin 1 | -0.0284656 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0281814 |
| LOXL2 | lysyl oxidase-like 2 | -0.0281047 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0280419 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.028002 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0279998 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0278656 |
| RPL12 | ribosomal protein L12 | -0.0278521 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0278264 |
| FTL | ferritin, light polypeptide | -0.027682 |
| CCND1 | cyclin D1 | -0.0272502 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0272473 |
| LMO7 | LIM domain 7 | -0.0272035 |
