| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Benproperine (phosphate)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAML2 | mastermind-like 2 (Drosophila) | 0.0837907 |
| ATXN1 | ataxin 1 | 0.0529265 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0483954 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0483371 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0391011 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0351517 |
| PCBP2 | poly(rC) binding protein 2 | 0.0346516 |
| KLHL29 | kelch-like family member 29 | 0.0318502 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0296555 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0267236 |
| NPSR1 | neuropeptide S receptor 1 | 0.0265783 |
| INTS6 | integrator complex subunit 6 | 0.0258159 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0254822 |
| VEGFA | vascular endothelial growth factor A | 0.0251471 |
| EHBP1 | EH domain binding protein 1 | 0.0245877 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0237802 |
| CCNY | cyclin Y | 0.0227055 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0225485 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0217068 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0213701 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0209638 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0195475 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0194658 |
| KIF16B | kinesin family member 16B | 0.0190167 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0187538 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0183931 |
| AUTS2 | autism susceptibility candidate 2 | 0.0182874 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0181959 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0175814 |
| ZNF292 | zinc finger protein 292 | 0.0175177 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0175054 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0174008 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0172214 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.016789 |
| PTEN | phosphatase and tensin homolog | 0.0166997 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0165762 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0161097 |
| HKDC1 | hexokinase domain containing 1 | 0.016031 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0158026 |
| FAM13A | family with sequence similarity 13, member A | 0.0155385 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0155153 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0153916 |
| EXOC4 | exocyst complex component 4 | 0.015341 |
| RPS12 | ribosomal protein S12 | 0.015332 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0152591 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0148308 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0148026 |
| RAD51B | RAD51 paralog B | 0.0146219 |
| FNIP1 | folliculin interacting protein 1 | 0.014566 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0138561 |
| ARF4 | ADP-ribosylation factor 4 | 0.0135905 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0133226 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0132995 |
| FOXO3 | forkhead box O3 | 0.0131552 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0129807 |
| YEATS2 | YEATS domain containing 2 | 0.0129542 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | 0.0129118 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0128661 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0127955 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0127766 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0125929 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0125874 |
| GTPBP2 | GTP binding protein 2 | 0.0125689 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0125652 |
| FLNB | filamin B, beta | 0.0123229 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0122735 |
| EGFR | epidermal growth factor receptor | 0.012265 |
| SNX13 | sorting nexin 13 | 0.0122184 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0121135 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0120067 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0119645 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0116859 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0116837 |
| MED13L | mediator complex subunit 13-like | 0.0116566 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0115016 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0114468 |
| NDRG1 | N-myc downstream regulated 1 | 0.0114443 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0114175 |
| MCL1 | myeloid cell leukemia 1 | 0.0113808 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0112723 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0112191 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0111774 |
| RYK | receptor-like tyrosine kinase | 0.0111608 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0109362 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.010768 |
| XYLT1 | xylosyltransferase I | 0.0107521 |
| PRELID2 | PRELI domain containing 2 | 0.0107312 |
| NABP1 | nucleic acid binding protein 1 | 0.0106744 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.010626 |
| COG5 | component of oligomeric golgi complex 5 | 0.0106233 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0105233 |
| STK17A | serine/threonine kinase 17a | 0.0104654 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0104578 |
| ANXA1 | annexin A1 | 0.0103804 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0103726 |
| PGM3 | phosphoglucomutase 3 | 0.0102581 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0102527 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0102422 |
| HELZ | helicase with zinc finger | 0.0102267 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0102233 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | -0.272068 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.170385 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.163601 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.120217 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.101457 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0975393 |
| TMC5 | transmembrane channel-like 5 | -0.0826563 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0820516 |
| H1-0 | H1.0 linker histone | -0.0655103 |
| AGR2 | anterior gradient 2 | -0.0647888 |
| ANXA2 | annexin A2 | -0.0618487 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0563902 |
| TMSB10 | thymosin beta 10 | -0.0562164 |
| S100A10 | S100 calcium binding protein A10 | -0.0550941 |
| LMO7 | LIM domain 7 | -0.0518953 |
| EPCAM | epithelial cell adhesion molecule | -0.0506204 |
| RRBP1 | ribosome binding protein 1 | -0.0498887 |
| CALR | calreticulin | -0.0493304 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0493174 |
| PTMA | prothymosin, alpha | -0.0491939 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0466939 |
| B2M | beta-2-microglobulin | -0.0455465 |
| HLA-E | major histocompatibility complex, class I, E | -0.0443457 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0422973 |
| ACTN4 | actinin, alpha 4 | -0.0405842 |
| KRT18 | keratin 18, type I | -0.0402368 |
| CD2AP | CD2-associated protein | -0.0399411 |
| S100A6 | S100 calcium binding protein A6 | -0.0395764 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0382435 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0379678 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0365331 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0364614 |
| MUC17 | mucin 17, cell surface associated | -0.0362995 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0355927 |
| TMEM123 | transmembrane protein 123 | -0.0354797 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0353244 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0351437 |
| EMP1 | epithelial membrane protein 1 | -0.0340705 |
| ACTG1 | actin gamma 1 | -0.0338973 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0336365 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0334393 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0332793 |
| HLA-C | major histocompatibility complex, class I, C | -0.0321292 |
| RPL35A | ribosomal protein L35a | -0.0316157 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0314111 |
| TMEM45B | transmembrane protein 45B | -0.0311843 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0309607 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0309336 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0307984 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.030784 |
| RAB7A | RAB7A, member RAS oncogene family | -0.030647 |
| MCU | mitochondrial calcium uniporter | -0.0306413 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0288985 |
| PRSS3 | protease, serine, 3 | -0.0286928 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0280851 |
| SEPTIN9 | septin 9 | -0.0277422 |
| RPL19 | ribosomal protein L19 | -0.0276725 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0262469 |
| RNF213 | ring finger protein 213 | -0.0261938 |
| DSG2 | desmoglein 2 | -0.0258243 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0254879 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0254116 |
| HLA-A | major histocompatibility complex, class I, A | -0.0253468 |
| CANX | calnexin | -0.0253299 |
| FTL | ferritin, light polypeptide | -0.025117 |
| RPL8 | ribosomal protein L8 | -0.0251099 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0251097 |
| GPX2 | glutathione peroxidase 2 | -0.0245293 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0244824 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0244744 |
| MUC13 | mucin 13, cell surface associated | -0.0242606 |
| XAF1 | XIAP associated factor 1 | -0.0242296 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0240172 |
| H3-3B | H3.3 histone B | -0.0239171 |
| MYO1E | myosin IE | -0.0237948 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0235653 |
| RPL34 | ribosomal protein L34 | -0.0234666 |
| MKI67 | marker of proliferation Ki-67 | -0.0231825 |
| PLSCR1 | phospholipid scramblase 1 | -0.0231771 |
| TMSB4X | thymosin beta 4, X-linked | -0.0226724 |
| INSIG1 | insulin induced gene 1 | -0.0225666 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0225654 |
| SHROOM3 | shroom family member 3 | -0.0225136 |
| HMGB1 | high mobility group box 1 | -0.0223056 |
| WDR45B | WD repeat domain 45B | -0.0221382 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0221172 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0214362 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0212416 |
| AOPEP | aminopeptidase O (putative) | -0.0210708 |
| RPLP1 | ribosomal protein, large, P1 | -0.0210548 |
| S100A9 | S100 calcium binding protein A9 | -0.0207084 |
| RPL23 | ribosomal protein L23 | -0.0205441 |
| ARF1 | ADP-ribosylation factor 1 | -0.0204177 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0203406 |
| RPS25 | ribosomal protein S25 | -0.0200857 |
| S100A11 | S100 calcium binding protein A11 | -0.0200027 |
| TPM4 | tropomyosin 4 | -0.0199447 |
| MGAM2 | maltase-glucoamylase 2 (putative) | -0.0199434 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.019736 |
| HDLBP | high density lipoprotein binding protein | -0.0195929 |