| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.081984 |
| VCL | vinculin | 0.0683973 |
| NPSR1 | neuropeptide S receptor 1 | 0.0653948 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.058803 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0558134 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0551579 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.054817 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0489632 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0469461 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0459303 |
| POTEF | POTE ankyrin domain family, member F | 0.0444536 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0443886 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0440681 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0428286 |
| MYO1E | myosin IE | 0.0414511 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0404091 |
| PCBP2 | poly(rC) binding protein 2 | 0.039742 |
| ASPH | aspartate beta-hydroxylase | 0.0390982 |
| FAT1 | FAT atypical cadherin 1 | 0.0386572 |
| EGFR | epidermal growth factor receptor | 0.0373472 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0357053 |
| FLNB | filamin B, beta | 0.0356215 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0348138 |
| TMSB10 | thymosin beta 10 | 0.0341464 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0340739 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0336842 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0325393 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0324794 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0317173 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0313101 |
| RNF217 | ring finger protein 217 | 0.0309785 |
| TPM4 | tropomyosin 4 | 0.0308729 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0300911 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0299461 |
| RCOR1 | REST corepressor 1 | 0.0299219 |
| RPS12 | ribosomal protein S12 | 0.0296135 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0284321 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0277202 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0273661 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0266818 |
| ACTG1 | actin gamma 1 | 0.0262711 |
| KRT8 | keratin 8, type II | 0.0258394 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0247329 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0247034 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0245307 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.024374 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0234728 |
| PARD3 | par-3 family cell polarity regulator | 0.0234424 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0230708 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0228713 |
| FBXO11 | F-box protein 11 | 0.0225662 |
| USP53 | ubiquitin specific peptidase 53 | 0.0224258 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0221683 |
| GPR39 | G protein-coupled receptor 39 | 0.0219955 |
| SNX9 | sorting nexin 9 | 0.0218735 |
| DIAPH1 | diaphanous-related formin 1 | 0.0218482 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0217136 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0216992 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0214182 |
| LAMA4 | laminin, alpha 4 | 0.021374 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0208101 |
| CLOCK | clock circadian regulator | 0.0207911 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0207203 |
| SVIL | supervillin | 0.0207142 |
| ANXA3 | annexin A3 | 0.0205022 |
| FOSL1 | FOS-like antigen 1 | 0.0204804 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.020026 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0199636 |
| MUC17 | mucin 17, cell surface associated | 0.019861 |
| INTS6 | integrator complex subunit 6 | 0.0198387 |
| CALB1 | calbindin 1, 28kDa | 0.0196874 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0194079 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0193092 |
| TES | testin LIM domain protein | 0.0192497 |
| PCDH9 | protocadherin 9 | 0.0190592 |
| TPM3 | tropomyosin 3 | 0.0186619 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0186132 |
| ECT2 | epithelial cell transforming 2 | 0.0183362 |
| S100A6 | S100 calcium binding protein A6 | 0.0182355 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.017974 |
| VCAN | versican | 0.0179529 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0178867 |
| TFF1 | trefoil factor 1 | 0.0174259 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0174213 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0171124 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0170144 |
| SIK3 | SIK family kinase 3 | 0.0168123 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0163307 |
| SLMAP | sarcolemma associated protein | 0.016062 |
| NABP1 | nucleic acid binding protein 1 | 0.0156099 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0155207 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0155106 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0154474 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0153483 |
| TRAM1 | translocation associated membrane protein 1 | 0.0152355 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0152306 |
| KRT18 | keratin 18, type I | 0.0151831 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0150879 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0150731 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0150524 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.182683 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.1407 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.136717 |
| PTMA | prothymosin, alpha | -0.113591 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0885756 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0873718 |
| RNF43 | ring finger protein 43 | -0.0866019 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0856506 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0751645 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0743359 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0665081 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.065683 |
| NDRG1 | N-myc downstream regulated 1 | -0.0638627 |
| H1-0 | H1.0 linker histone | -0.0625233 |
| GPHN | gephyrin | -0.058953 |
| GOLGA4 | golgin A4 | -0.0577542 |
| TNS4 | tensin 4 | -0.0565403 |
| PRSS3 | protease, serine, 3 | -0.0516082 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0494384 |
| HDLBP | high density lipoprotein binding protein | -0.0481933 |
| RRBP1 | ribosome binding protein 1 | -0.0477274 |
| FAM13A | family with sequence similarity 13, member A | -0.0468221 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0468122 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0454611 |
| OGA | O-GlcNAcase | -0.0453153 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0450147 |
| NEBL | nebulette | -0.0443671 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0442845 |
| PCDHB16 | protocadherin beta 16 | -0.0427105 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0415495 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0412702 |
| CD44 | CD44 molecule (Indian blood group) | -0.0404854 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.040199 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0399495 |
| NFIA | nuclear factor I/A | -0.0395007 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0390193 |
| RBM39 | RNA binding motif protein 39 | -0.0387307 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0380257 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0379408 |
| CANX | calnexin | -0.0374514 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0372765 |
| PRELID2 | PRELI domain containing 2 | -0.037199 |
| ANXA2 | annexin A2 | -0.0368605 |
| TRIM2 | tripartite motif containing 2 | -0.0362742 |
| EPCAM | epithelial cell adhesion molecule | -0.0358539 |
| AGR2 | anterior gradient 2 | -0.0346784 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0344768 |
| PIGR | polymeric immunoglobulin receptor | -0.0336324 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.033573 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0333557 |
| GDF15 | growth differentiation factor 15 | -0.0332203 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0320019 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0318795 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.031805 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0314995 |
| CADPS | Ca++-dependent secretion activator | -0.0310924 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0309599 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0306725 |
| AHNAK | AHNAK nucleoprotein | -0.0306529 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.0306086 |
| RPLP1 | ribosomal protein, large, P1 | -0.0304049 |
| NF1 | neurofibromin 1 | -0.0302726 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0302116 |
| ONECUT3 | one cut homeobox 3 | -0.0301943 |
| WDR45B | WD repeat domain 45B | -0.0298152 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0294603 |
| ACTN4 | actinin, alpha 4 | -0.0291364 |
| SHROOM3 | shroom family member 3 | -0.0289844 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0288703 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.028729 |
| CALR | calreticulin | -0.0284961 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0278605 |
| ATXN1 | ataxin 1 | -0.0277786 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0275819 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0273342 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0271027 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0269926 |
| RPL34 | ribosomal protein L34 | -0.0269918 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0268541 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0266847 |
| ABHD17C | abhydrolase domain containing 17C | -0.0263257 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0262913 |
| ARF1 | ADP-ribosylation factor 1 | -0.0261008 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0260088 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0259682 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0258912 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0258175 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0257697 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0255836 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0255815 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0254635 |
| TXNRD1 | thioredoxin reductase 1 | -0.0251997 |
| EREG | epiregulin | -0.025009 |
| EXPH5 | exophilin 5 | -0.0249694 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0245705 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0245401 |
| ABLIM1 | actin binding LIM protein 1 | -0.0245146 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0244534 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0243079 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0243 |
