| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Benproperine (phosphate)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TOP1 | topoisomerase (DNA) I | 0.0505711 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0449247 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0414014 |
| ATP13A3 | ATPase type 13A3 | 0.0377003 |
| UVRAG | UV radiation resistance associated | 0.0345863 |
| RNF145 | ring finger protein 145 | 0.031311 |
| PGK1 | phosphoglycerate kinase 1 | 0.025512 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0247256 |
| ANXA5 | annexin A5 | 0.0224428 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0218371 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0206527 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0203428 |
| USP3 | ubiquitin specific peptidase 3 | 0.0196446 |
| SLMAP | sarcolemma associated protein | 0.0194197 |
| TMSB10 | thymosin beta 10 | 0.0191359 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.018536 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0183599 |
| SCEL | sciellin | 0.0183178 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0179707 |
| NCKAP1 | NCK-associated protein 1 | 0.0169562 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0162126 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0160048 |
| ECT2 | epithelial cell transforming 2 | 0.0159855 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0155333 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0142933 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0141962 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0141736 |
| NUP58 | nucleoporin 58 | 0.0138878 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0138836 |
| PARD3 | par-3 family cell polarity regulator | 0.0138806 |
| KRT7 | keratin 7, type II | 0.0137072 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0136326 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0131465 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0130936 |
| CD163L1 | CD163 molecule-like 1 | 0.0128185 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0127434 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0126101 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0121578 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.012153 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0116588 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0116186 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0114002 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0112073 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0110979 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0109629 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0108882 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0107602 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0104486 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0103395 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0100541 |
| OLA1 | Obg-like ATPase 1 | 0.00996641 |
| CPNE8 | copine VIII | 0.0096888 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.00965519 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00964448 |
| SLC35F3 | solute carrier family 35, member F3 | 0.00947022 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.00943792 |
| USP12 | ubiquitin specific peptidase 12 | 0.00940581 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.00938617 |
| WDR43 | WD repeat domain 43 | 0.00914253 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.00909151 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.00901649 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.00881632 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0086068 |
| TFG | TRK-fused gene | 0.0085929 |
| QKI | QKI, KH domain containing, RNA binding | 0.00855673 |
| ELOVL7 | ELOVL fatty acid elongase 7 | 0.00854732 |
| ANXA2 | annexin A2 | 0.00847583 |
| MATR3 | matrin 3 | 0.00845973 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.00844959 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.00838508 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0083736 |
| GPC5 | glypican 5 | 0.00829075 |
| CASC3 | cancer susceptibility candidate 3 | 0.00817538 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.00816389 |
| AMOTL1 | angiomotin like 1 | 0.00811962 |
| PUM2 | pumilio RNA-binding family member 2 | 0.00790267 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.00780653 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.00769785 |
| FLNB | filamin B, beta | 0.00767617 |
| MYOF | myoferlin | 0.00766729 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.00759501 |
| NHSL1 | NHS-like 1 | 0.00744051 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.00731062 |
| TNS3 | tensin 3 | 0.00728788 |
| CNKSR3 | CNKSR family member 3 | 0.00719225 |
| PTK2 | protein tyrosine kinase 2 | 0.00710436 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00703482 |
| CFAP20DC | CFAP20 domain containing | 0.00700081 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.00699956 |
| FRMD6 | FERM domain containing 6 | 0.00699203 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00698181 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00693425 |
| CHML | choroideremia-like (Rab escort protein 2) | 0.00693071 |
| EIF4E | eukaryotic translation initiation factor 4E | 0.00692764 |
| WTAP | Wilms tumor 1 associated protein | 0.0069196 |
| RAB27B | RAB27B, member RAS oncogene family | 0.00685535 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0068454 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00677372 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.00676653 |
| ACTG1 | actin gamma 1 | 0.00676267 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.264738 |
| TXNRD1 | thioredoxin reductase 1 | -0.130241 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.122709 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.100792 |
| NDRG1 | N-myc downstream regulated 1 | -0.084935 |
| MT2A | metallothionein 2A | -0.0730314 |
| LAMC2 | laminin, gamma 2 | -0.0632209 |
| EGFR | epidermal growth factor receptor | -0.0626755 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0582865 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0522578 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0516059 |
| CES1 | carboxylesterase 1 | -0.0505403 |
| TBC1D22A | TBC1 domain family, member 22A | -0.048846 |
| FAM13A | family with sequence similarity 13, member A | -0.0474891 |
| GOLGB1 | golgin B1 | -0.0444488 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0431445 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0427081 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.040541 |
| USP34 | ubiquitin specific peptidase 34 | -0.0400269 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0392113 |
| CANX | calnexin | -0.039149 |
| MKI67 | marker of proliferation Ki-67 | -0.0390368 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0389995 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0389943 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0389389 |
| MCL1 | myeloid cell leukemia 1 | -0.038695 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0385993 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0384413 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0371859 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0370239 |
| JMJD1C | jumonji domain containing 1C | -0.0362447 |
| UBC | ubiquitin C | -0.0358046 |
| SLTM | SAFB-like, transcription modulator | -0.0349048 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0348271 |
| PKM | pyruvate kinase, muscle | -0.0322552 |
| RBM39 | RNA binding motif protein 39 | -0.0310959 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0309623 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0309058 |
| RPS3 | ribosomal protein S3 | -0.0308134 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0305113 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.030118 |
| ZNF638 | zinc finger protein 638 | -0.0298839 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0298336 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0296641 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0296466 |
| OSMR | oncostatin M receptor | -0.0288603 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | -0.028725 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0282409 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0278428 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0273417 |
| HDLBP | high density lipoprotein binding protein | -0.0271763 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0271257 |
| RPS2 | ribosomal protein S2 | -0.0271038 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.026766 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0265491 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0265159 |
| CPE | carboxypeptidase E | -0.0261603 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0255185 |
| FTL | ferritin, light polypeptide | -0.025302 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0252774 |
| STC1 | stanniocalcin 1 | -0.0252284 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0252142 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0251019 |
| BRD2 | bromodomain containing 2 | -0.024678 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.024313 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0242456 |
| GOLGA4 | golgin A4 | -0.0241981 |
| TMF1 | TATA element modulatory factor 1 | -0.0241765 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0239956 |
| SON | SON DNA binding protein | -0.0234923 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0234159 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0233288 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0229044 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0228112 |
| CEP350 | centrosomal protein 350kDa | -0.0227856 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0227512 |
| SYAP1 | synapse associated protein 1 | -0.0225003 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0224567 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.022456 |
| LAMA4 | laminin, alpha 4 | -0.0223767 |
| ADAR | adenosine deaminase, RNA-specific | -0.0223712 |
| CTTN | cortactin | -0.022086 |
| RPL7 | ribosomal protein L7 | -0.0219317 |
| NABP1 | nucleic acid binding protein 1 | -0.0219102 |
| EP300 | E1A binding protein p300 | -0.0218765 |
| KIAA1217 | KIAA1217 | -0.0216874 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0216808 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0212565 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0211674 |
| SEC61G | Sec61 gamma subunit | -0.0210819 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0209799 |
| RPLP1 | ribosomal protein, large, P1 | -0.0209166 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0208818 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.020857 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0208315 |
| ANO6 | anoctamin 6 | -0.0207899 |
| LDHA | lactate dehydrogenase A | -0.0207146 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0204277 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0204166 |
| MYO1E | myosin IE | -0.02034 |
