| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0647437 |
| MT2A | metallothionein 2A | 0.0634115 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0546176 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0501856 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0448397 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0439048 |
| USP3 | ubiquitin specific peptidase 3 | 0.0430913 |
| PTK2 | protein tyrosine kinase 2 | 0.0420116 |
| ATP13A3 | ATPase type 13A3 | 0.0414241 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0399408 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0350175 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0337915 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0318585 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0285118 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0282508 |
| NCKAP1 | NCK-associated protein 1 | 0.0268701 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0266346 |
| MTSS1 | metastasis suppressor 1 | 0.0259785 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0256525 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0252345 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0251062 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0249746 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0248429 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0246796 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0246213 |
| CDH13 | cadherin 13 | 0.0244532 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0242421 |
| MED13L | mediator complex subunit 13-like | 0.0238016 |
| PARD3 | par-3 family cell polarity regulator | 0.0237465 |
| NUP58 | nucleoporin 58 | 0.0234767 |
| NPTN | neuroplastin | 0.0234719 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0234459 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0234037 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0224728 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0224165 |
| MYO1B | myosin IB | 0.0223259 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0223104 |
| NRG1 | neuregulin 1 | 0.0220753 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0217695 |
| FOXJ3 | forkhead box J3 | 0.0216832 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0215188 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0213905 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0213023 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0211797 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0205081 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0204205 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0203896 |
| STC1 | stanniocalcin 1 | 0.0202989 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0201128 |
| JMJD1C | jumonji domain containing 1C | 0.0199412 |
| CDC73 | cell division cycle 73 | 0.0199202 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.019671 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0195567 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0195533 |
| RPL31 | ribosomal protein L31 | 0.0194519 |
| RPS24 | ribosomal protein S24 | 0.0193716 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.019217 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.018942 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.018802 |
| WDR43 | WD repeat domain 43 | 0.018776 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0185578 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0184191 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0182516 |
| POU2F1 | POU class 2 homeobox 1 | 0.0179922 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0178545 |
| SRPK2 | SRSF protein kinase 2 | 0.0176795 |
| MEMO1 | mediator of cell motility 1 | 0.0176368 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0176283 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0175285 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0175206 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0171438 |
| FTL | ferritin, light polypeptide | 0.0170171 |
| RBM33 | RNA binding motif protein 33 | 0.0169651 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.016956 |
| RPS5 | ribosomal protein S5 | 0.0167669 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0167363 |
| RNF145 | ring finger protein 145 | 0.016693 |
| BMP2K | BMP2 inducible kinase | 0.0162655 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0162496 |
| HBS1L | HBS1-like translational GTPase | 0.0162225 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.01621 |
| TOP1 | topoisomerase (DNA) I | 0.0161033 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0160066 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0159912 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0158695 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0158295 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0155679 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0155564 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0155384 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0155129 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0155086 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0155075 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0153337 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0152952 |
| TKT | transketolase | 0.0152876 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0152759 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.015159 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0151464 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0151463 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0151357 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.123136 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.114331 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.104297 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0995384 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0821315 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0718594 |
| FAM20C | family with sequence similarity 20, member C | -0.0615444 |
| PRELID2 | PRELI domain containing 2 | -0.0594083 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.0581416 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0578699 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0574872 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0559825 |
| SMAD3 | SMAD family member 3 | -0.0556309 |
| LOX | lysyl oxidase | -0.0539874 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0532756 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0523853 |
| GOLGA4 | golgin A4 | -0.0495168 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0494878 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0494518 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0486456 |
| ATXN1 | ataxin 1 | -0.0486189 |
| RAD51B | RAD51 paralog B | -0.0485095 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.048033 |
| FBXO32 | F-box protein 32 | -0.0448574 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.044614 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0440844 |
| ETV6 | ets variant 6 | -0.0424943 |
| CALU | calumenin | -0.0420684 |
| OSMR | oncostatin M receptor | -0.0414829 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0409214 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0397167 |
| USP34 | ubiquitin specific peptidase 34 | -0.0391216 |
| RAI14 | retinoic acid induced 14 | -0.0389129 |
| SYAP1 | synapse associated protein 1 | -0.0386761 |
| CANX | calnexin | -0.0385795 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0381977 |
| LOXL2 | lysyl oxidase-like 2 | -0.0368109 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0367677 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0359896 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0359525 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0342834 |
| CA12 | carbonic anhydrase XII | -0.0331674 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0329996 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0322789 |
| TPR | translocated promoter region, nuclear basket protein | -0.0322785 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.032235 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0321517 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0313138 |
| HDLBP | high density lipoprotein binding protein | -0.0309561 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0303395 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0300803 |
| RBM39 | RNA binding motif protein 39 | -0.0297575 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0291726 |
| ATM | ATM serine/threonine kinase | -0.0285893 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0285615 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0284777 |
| EGR1 | early growth response 1 | -0.028381 |
| TMEM263 | transmembrane protein 263 | -0.028235 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0282271 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0279486 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0278419 |
| PRKCSH | protein kinase C substrate 80K-H | -0.0276094 |
| SQSTM1 | sequestosome 1 | -0.0275035 |
| MX2 | MX dynamin-like GTPase 2 | -0.0273732 |
| EFNA5 | ephrin-A5 | -0.0272873 |
| AOPEP | aminopeptidase O (putative) | -0.0272076 |
| EGFR | epidermal growth factor receptor | -0.0269959 |
| JUN | jun proto-oncogene | -0.0269595 |
| METTL15 | methyltransferase like 15 | -0.026461 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0264053 |
| EHBP1 | EH domain binding protein 1 | -0.0262798 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0262363 |
| ANXA2 | annexin A2 | -0.0258744 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0257403 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0255424 |
| ARF4 | ADP-ribosylation factor 4 | -0.0254129 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.025381 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0253792 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0252006 |
| HDAC9 | histone deacetylase 9 | -0.0251588 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0249352 |
| GPC6 | glypican 6 | -0.0241649 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.024118 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0238852 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0238692 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0231991 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0230926 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0230039 |
| SNX6 | sorting nexin 6 | -0.0226458 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0225663 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0223595 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.0223591 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0222248 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0221734 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0221322 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0220745 |
| EXOC4 | exocyst complex component 4 | -0.0219495 |
| NAV2 | neuron navigator 2 | -0.0219077 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0218965 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0216968 |
