| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0991241 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.099017 |
| SQSTM1 | sequestosome 1 | 0.0948975 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0803387 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0793383 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0789422 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.078527 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0754324 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0742059 |
| FNIP1 | folliculin interacting protein 1 | 0.070219 |
| ZNF207 | zinc finger protein 207 | 0.069919 |
| PCBP3 | poly(rC) binding protein 3 | 0.0690574 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0650909 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0624718 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0621324 |
| FAT1 | FAT atypical cadherin 1 | 0.0608008 |
| MYO6 | myosin VI | 0.0593381 |
| NEK7 | NIMA-related kinase 7 | 0.0591547 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0584699 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0570326 |
| SETX | senataxin | 0.0564299 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0553199 |
| ZNF292 | zinc finger protein 292 | 0.0545401 |
| NDRG1 | N-myc downstream regulated 1 | 0.0541596 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0535393 |
| CDC42 | cell division cycle 42 | 0.0533178 |
| YAF2 | YY1 associated factor 2 | 0.0529338 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0521402 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0491752 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0487658 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0485313 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0477788 |
| MYOF | myoferlin | 0.0475373 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0464464 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0455082 |
| EP300 | E1A binding protein p300 | 0.0451858 |
| EGFR | epidermal growth factor receptor | 0.0446976 |
| PTK2 | protein tyrosine kinase 2 | 0.0436566 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0425653 |
| PHF3 | PHD finger protein 3 | 0.0419758 |
| RORA | RAR-related orphan receptor A | 0.0418039 |
| TMSB4X | thymosin beta 4, X-linked | 0.0415892 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0413906 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0410286 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0400637 |
| MICU1 | mitochondrial calcium uptake 1 | 0.0399309 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0397936 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0393698 |
| RPL34 | ribosomal protein L34 | 0.0391948 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0390334 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0390259 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0383459 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0382937 |
| ANXA2 | annexin A2 | 0.0382477 |
| SMAD2 | SMAD family member 2 | 0.0381093 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0372445 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0369723 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0350079 |
| SRPK2 | SRSF protein kinase 2 | 0.03443 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0344184 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0343717 |
| FBXO11 | F-box protein 11 | 0.0342231 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0341458 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0339444 |
| ERBIN | erbb2 interacting protein | 0.0333173 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0330212 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0328838 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0328326 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0327607 |
| JMJD1C | jumonji domain containing 1C | 0.0323344 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0311951 |
| LAMA4 | laminin, alpha 4 | 0.0309504 |
| RPS27A | ribosomal protein S27a | 0.0309131 |
| TXNRD1 | thioredoxin reductase 1 | 0.030873 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0306739 |
| FLNB | filamin B, beta | 0.0306547 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0303582 |
| PDE10A | phosphodiesterase 10A | 0.0302734 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0302223 |
| STC1 | stanniocalcin 1 | 0.0296325 |
| RPS16 | ribosomal protein S16 | 0.0293624 |
| RPL11 | ribosomal protein L11 | 0.0292454 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0291707 |
| CLTC | clathrin, heavy chain (Hc) | 0.0289106 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.028697 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0278312 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0276492 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0270024 |
| TPM4 | tropomyosin 4 | 0.0268477 |
| RPS12 | ribosomal protein S12 | 0.0262933 |
| CREBRF | CREB3 regulatory factor | 0.0261435 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0260048 |
| ZNF638 | zinc finger protein 638 | 0.0257333 |
| ENO1 | enolase 1, (alpha) | 0.0254489 |
| ANXA1 | annexin A1 | 0.0246907 |
| CALR | calreticulin | 0.024668 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0243118 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0238479 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0237816 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0234734 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.107138 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0917469 |
| CCNI | cyclin I | -0.0884651 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0852638 |
| OGA | O-GlcNAcase | -0.0723885 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0709371 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0696444 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0686412 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0685141 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0675273 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0666225 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0665979 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0659279 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0653988 |
| FAM13A | family with sequence similarity 13, member A | -0.0649543 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0621205 |
| S100A10 | S100 calcium binding protein A10 | -0.0611545 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0611404 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0603456 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0599638 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0591938 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0573242 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0572034 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0570452 |
| CANX | calnexin | -0.0568735 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0547635 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -0.0547578 |
| HDLBP | high density lipoprotein binding protein | -0.0546425 |
| MRTFA | myocardin related transcription factor A | -0.0539148 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0538562 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0520032 |
| GOLGA4 | golgin A4 | -0.0499092 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0496302 |
| TPR | translocated promoter region, nuclear basket protein | -0.0492703 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0489021 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0488595 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0483341 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0477503 |
| RAD51B | RAD51 paralog B | -0.046611 |
| FTL | ferritin, light polypeptide | -0.0465758 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0461622 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0458997 |
| ETNK1 | ethanolamine kinase 1 | -0.0449164 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0443959 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0443845 |
| IRS2 | insulin receptor substrate 2 | -0.0441956 |
| NUP58 | nucleoporin 58 | -0.0438405 |
| MT2A | metallothionein 2A | -0.0431559 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0421307 |
| PKM | pyruvate kinase, muscle | -0.040915 |
| RPL37 | ribosomal protein L37 | -0.0408186 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0398333 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.039411 |
| RUNX1 | runt-related transcription factor 1 | -0.0388001 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0386814 |
| RPL23 | ribosomal protein L23 | -0.0382789 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0377968 |
| NAV2 | neuron navigator 2 | -0.0377937 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0377438 |
| SETD5 | SET domain containing 5 | -0.0376463 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0375009 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0372081 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0369304 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0363065 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0362421 |
| B2M | beta-2-microglobulin | -0.0361929 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0359689 |
| PGK1 | phosphoglycerate kinase 1 | -0.0351248 |
| PTMA | prothymosin, alpha | -0.0348679 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.034795 |
| SIK3 | SIK family kinase 3 | -0.034645 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0343074 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0333691 |
| PCBP2 | poly(rC) binding protein 2 | -0.0330671 |
| SLC38A1 | solute carrier family 38, member 1 | -0.032954 |
| MED13 | mediator complex subunit 13 | -0.0322113 |
| SH3D19 | SH3 domain containing 19 | -0.0321542 |
| RPS20 | ribosomal protein S20 | -0.0320357 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0319616 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0314472 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0312499 |
| HELZ | helicase with zinc finger | -0.0308537 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0307596 |
| RPL32 | ribosomal protein L32 | -0.0297435 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0291358 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0290016 |
| RPS17 | ribosomal protein S17 | -0.0276732 |
| ZFHX3 | zinc finger homeobox 3 | -0.0276035 |
| RNF145 | ring finger protein 145 | -0.0269194 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0269188 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0264638 |
| SMYD3 | SET and MYND domain containing 3 | -0.0261201 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0261192 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0254592 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0252821 |
| TENM3 | teneurin transmembrane protein 3 | -0.0247694 |
| RPS8 | ribosomal protein S8 | -0.0243581 |
| NGLY1 | N-glycanase 1 | -0.0242661 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0240116 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0231134 |
