| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.105079 |
| PEG10 | paternally expressed 10 | 0.0863897 |
| ZNF292 | zinc finger protein 292 | 0.0620522 |
| ENAH | enabled homolog (Drosophila) | 0.0619335 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0582329 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0537767 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0494513 |
| USP25 | ubiquitin specific peptidase 25 | 0.049445 |
| PDGFC | platelet derived growth factor C | 0.0490728 |
| NTM | neurotrimin | 0.0469297 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0452541 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0449411 |
| MED13L | mediator complex subunit 13-like | 0.0399803 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0398446 |
| USP3 | ubiquitin specific peptidase 3 | 0.036669 |
| THBS1 | thrombospondin 1 | 0.0358114 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0355864 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0355355 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0346626 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0343388 |
| MTF2 | metal response element binding transcription factor 2 | 0.0333686 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.032995 |
| ZNF608 | zinc finger protein 608 | 0.0320291 |
| INTS13 | integrator complex subunit 13 | 0.0319707 |
| CDK6 | cyclin-dependent kinase 6 | 0.0312894 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0307983 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0306729 |
| BRMS1L | breast cancer metastasis-suppressor 1-like | 0.030556 |
| WDR43 | WD repeat domain 43 | 0.0298387 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.029647 |
| TMEM64 | transmembrane protein 64 | 0.0293268 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0289482 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0281047 |
| CRY1 | cryptochrome circadian clock 1 | 0.0279161 |
| NCKAP1 | NCK-associated protein 1 | 0.027836 |
| TPM3 | tropomyosin 3 | 0.0277778 |
| ANXA5 | annexin A5 | 0.0275154 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0274401 |
| SFRP4 | secreted frizzled-related protein 4 | 0.02744 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0273699 |
| RHOH | ras homolog family member H | 0.0272507 |
| HDAC9 | histone deacetylase 9 | 0.027159 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0269324 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0268447 |
| MEMO1 | mediator of cell motility 1 | 0.0266577 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0265939 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0263385 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0262226 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0261952 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0261228 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0255376 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0253861 |
| PLK2 | polo-like kinase 2 | 0.0253763 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0253395 |
| TMEM123 | transmembrane protein 123 | 0.0248999 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0244933 |
| MTPN | myotrophin | 0.0244395 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0240171 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0238611 |
| RYBP | RING1 and YY1 binding protein | 0.0236022 |
| WDR26 | WD repeat domain 26 | 0.0235983 |
| RFX7 | regulatory factor X, 7 | 0.0235471 |
| QKI | QKI, KH domain containing, RNA binding | 0.0232989 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0232831 |
| ZNF711 | zinc finger protein 711 | 0.023273 |
| CCN2 | cellular communication network factor 2 | 0.0232444 |
| FERMT2 | fermitin family member 2 | 0.0231811 |
| NUP153 | nucleoporin 153kDa | 0.0230494 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0223295 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0221801 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0220311 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.022012 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0217972 |
| SET | SET nuclear proto-oncogene | 0.0216777 |
| RNF145 | ring finger protein 145 | 0.0215486 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0211597 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0210729 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0206991 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0206175 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0205267 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0204966 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0204963 |
| USP24 | ubiquitin specific peptidase 24 | 0.0203764 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.020199 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0201058 |
| UBP1 | upstream binding protein 1 (LBP-1a) | 0.020091 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.020026 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0199597 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.019853 |
| NDC1 | NDC1 transmembrane nucleoporin | 0.0196883 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.019634 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0195282 |
| BTG3 | BTG family, member 3 | 0.0194476 |
| SETD2 | SET domain containing 2 | 0.0194271 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0192552 |
| NEBL | nebulette | 0.0192525 |
| PDCD5 | programmed cell death 5 | 0.0192037 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0190675 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.0189815 |
| TUT4 | terminal uridylyl transferase 4 | 0.018964 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | -0.134163 |
| VIM | vimentin | -0.130329 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.123949 |
| TMSB10 | thymosin beta 10 | -0.117867 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.1034 |
| GPC3 | glypican 3 | -0.102816 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0877723 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0806918 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0747797 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.074344 |
| PCDH9 | protocadherin 9 | -0.0710135 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0686035 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.06402 |
| PTMA | prothymosin, alpha | -0.0633022 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0605926 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0577972 |
| RPS16 | ribosomal protein S16 | -0.0549408 |
| RAD51B | RAD51 paralog B | -0.0545036 |
| MKI67 | marker of proliferation Ki-67 | -0.0532182 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.052155 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0517686 |
| CENPF | centromere protein F, 350/400kDa | -0.0510376 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0509043 |
| FTL | ferritin, light polypeptide | -0.0490852 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0473766 |
| GNAS | GNAS complex locus | -0.0472934 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.046516 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0449865 |
| CALR | calreticulin | -0.0438141 |
| DEK | DEK proto-oncogene | -0.0437573 |
| PHIP | pleckstrin homology domain interacting protein | -0.0430526 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0422953 |
| TUBA1B | tubulin, alpha 1b | -0.042252 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0390723 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.038621 |
| RPLP1 | ribosomal protein, large, P1 | -0.037838 |
| CDH19 | cadherin 19, type 2 | -0.0372047 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0360511 |
| RPS6 | ribosomal protein S6 | -0.0360246 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0353996 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0352257 |
| COL3A1 | collagen, type III, alpha 1 | -0.0349046 |
| CEP350 | centrosomal protein 350kDa | -0.0346865 |
| ANXA2 | annexin A2 | -0.0343739 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0340207 |
| CUX1 | cut-like homeobox 1 | -0.0338362 |
| S100A10 | S100 calcium binding protein A10 | -0.0334598 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.033264 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0324414 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0319213 |
| NHSL1 | NHS-like 1 | -0.0318331 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0311698 |
| RASAL2 | RAS protein activator like 2 | -0.0310218 |
| HMGB1 | high mobility group box 1 | -0.0309634 |
| RPS8 | ribosomal protein S8 | -0.0308285 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0307856 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0307625 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0303357 |
| LDHA | lactate dehydrogenase A | -0.030055 |
| SGO2 | shugoshin 2 | -0.0299023 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0297868 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0296932 |
| RPL35A | ribosomal protein L35a | -0.0292866 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0292583 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0291227 |
| ATXN2 | ataxin 2 | -0.029073 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0283732 |
| USP34 | ubiquitin specific peptidase 34 | -0.0280962 |
| AHNAK | AHNAK nucleoprotein | -0.0278854 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0278847 |
| RPL37A | ribosomal protein L37a | -0.0278524 |
| RPL12 | ribosomal protein L12 | -0.0277927 |
| CENPE | centromere protein E, 312kDa | -0.0277419 |
| PCDH7 | protocadherin 7 | -0.0277249 |
| PROS1 | protein S (alpha) | -0.0276484 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0275745 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0272625 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | -0.0272237 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0271884 |
| SFTPA2 | surfactant protein A2 | -0.0261075 |
| RPL31 | ribosomal protein L31 | -0.0260319 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0259674 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0258685 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0254715 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0254519 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.025312 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0250291 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0250025 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0249393 |
| MORF4L2 | mortality factor 4 like 2 | -0.0248016 |
| ZNF638 | zinc finger protein 638 | -0.0247829 |
| RREB1 | ras responsive element binding protein 1 | -0.0246444 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0243941 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0243917 |
| NXN | nucleoredoxin | -0.0243267 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.024295 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0237522 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0235915 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0235841 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0235591 |
