| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | 0.0901447 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0577817 |
| ACTG1 | actin gamma 1 | 0.0570439 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0478981 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0467897 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0446551 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0434872 |
| INTS6 | integrator complex subunit 6 | 0.0423504 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0418485 |
| ASPH | aspartate beta-hydroxylase | 0.0410945 |
| RPL35A | ribosomal protein L35a | 0.0395039 |
| RPS27A | ribosomal protein S27a | 0.0381108 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0380844 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0372532 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0362051 |
| RPL37A | ribosomal protein L37a | 0.0359883 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0355384 |
| MYO6 | myosin VI | 0.0350648 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0344449 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.034165 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0337147 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0333094 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0331542 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0331278 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0326773 |
| PARD3 | par-3 family cell polarity regulator | 0.0322193 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.031916 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0315087 |
| AFDN | afadin, adherens junction formation factor | 0.0312239 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0306397 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0300358 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0290992 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0289205 |
| RPL31 | ribosomal protein L31 | 0.0287123 |
| CD2AP | CD2-associated protein | 0.0286434 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0282917 |
| LMO7 | LIM domain 7 | 0.0277776 |
| RAD51B | RAD51 paralog B | 0.0275115 |
| RASAL2 | RAS protein activator like 2 | 0.027105 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0265502 |
| MEF2A | myocyte enhancer factor 2A | 0.0257978 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0257531 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0256567 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0256453 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0256095 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0253507 |
| NCOA3 | nuclear receptor coactivator 3 | 0.02466 |
| LAMC2 | laminin, gamma 2 | 0.0246481 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0244909 |
| HMGA2 | high mobility group AT-hook 2 | 0.0243964 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0242121 |
| PTK2 | protein tyrosine kinase 2 | 0.0239043 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0238899 |
| RPS24 | ribosomal protein S24 | 0.0238406 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0233635 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0230022 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0228469 |
| MYO5B | myosin VB | 0.0225293 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0223895 |
| RPL38 | ribosomal protein L38 | 0.0222649 |
| ATP13A3 | ATPase type 13A3 | 0.0220822 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0219431 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0218088 |
| CNKSR3 | CNKSR family member 3 | 0.0217067 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0217029 |
| MED13L | mediator complex subunit 13-like | 0.0214043 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0213023 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0209401 |
| ACTN4 | actinin, alpha 4 | 0.020922 |
| SMAD3 | SMAD family member 3 | 0.020859 |
| EXOC4 | exocyst complex component 4 | 0.0207347 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0207331 |
| WAC | WW domain containing adaptor with coiled-coil | 0.020665 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0204156 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0201685 |
| RPS8 | ribosomal protein S8 | 0.0201586 |
| SYT14 | synaptotagmin XIV | 0.0201278 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.019918 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0198148 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.019719 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0196697 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0195894 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0195374 |
| AHNAK | AHNAK nucleoprotein | 0.0194604 |
| TLK2 | tousled-like kinase 2 | 0.0193732 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0192907 |
| KLC1 | kinesin light chain 1 | 0.0192609 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0192534 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0192026 |
| EGFR | epidermal growth factor receptor | 0.0191842 |
| SEPTIN9 | septin 9 | 0.0189514 |
| RYK | receptor-like tyrosine kinase | 0.0187375 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0186797 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.018553 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0183886 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0181944 |
| EHBP1 | EH domain binding protein 1 | 0.0181335 |
| AEBP2 | AE binding protein 2 | 0.0179365 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0178718 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0178336 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.342552 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.16505 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.128597 |
| NDRG1 | N-myc downstream regulated 1 | -0.124802 |
| LDHA | lactate dehydrogenase A | -0.0865748 |
| EZR | ezrin | -0.0800831 |
| TXNIP | thioredoxin interacting protein | -0.0668407 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0653753 |
| KRT19 | keratin 19, type I | -0.0651608 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0647399 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0638396 |
| FOSL1 | FOS-like antigen 1 | -0.062594 |
| HMGA1 | high mobility group AT-hook 1 | -0.0622207 |
| TMSB10 | thymosin beta 10 | -0.0543348 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0537899 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0534674 |
| EMP1 | epithelial membrane protein 1 | -0.0529706 |
| ANXA2 | annexin A2 | -0.0504642 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0492606 |
| EGR1 | early growth response 1 | -0.0476922 |
| TPI1 | triosephosphate isomerase 1 | -0.0476786 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0476083 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.046878 |
| GOLGA4 | golgin A4 | -0.0464202 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0457292 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0442122 |
| MT2A | metallothionein 2A | -0.0432624 |
| ANLN | anillin, actin binding protein | -0.0430071 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0422799 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0420945 |
| POTEF | POTE ankyrin domain family, member F | -0.0412624 |
| CCNL1 | cyclin L1 | -0.0404899 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0401679 |
| MKI67 | marker of proliferation Ki-67 | -0.0397841 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.03978 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0386496 |
| TGM2 | transglutaminase 2 | -0.0385508 |
| PKM | pyruvate kinase, muscle | -0.0383825 |
| ARF4 | ADP-ribosylation factor 4 | -0.0374343 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0362167 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0360937 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0354401 |
| ANXA1 | annexin A1 | -0.0352465 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0349892 |
| CDCP1 | CUB domain containing protein 1 | -0.0348097 |
| CANX | calnexin | -0.0347157 |
| B2M | beta-2-microglobulin | -0.034622 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0341788 |
| FAM3C | family with sequence similarity 3, member C | -0.0341684 |
| TPM4 | tropomyosin 4 | -0.0330123 |
| CENPF | centromere protein F, 350/400kDa | -0.0321405 |
| YBX3 | Y box binding protein 3 | -0.0320878 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0314892 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0314236 |
| HLA-A | major histocompatibility complex, class I, A | -0.0311774 |
| C3 | complement component 3 | -0.0299049 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0298828 |
| GOLGB1 | golgin B1 | -0.028997 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0284015 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0280903 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0274834 |
| PCBP2 | poly(rC) binding protein 2 | -0.027302 |
| MORF4L2 | mortality factor 4 like 2 | -0.0272182 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0270239 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0269379 |
| LAMA4 | laminin, alpha 4 | -0.0267301 |
| FTL | ferritin, light polypeptide | -0.0261627 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0260915 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0259599 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0259529 |
| IRS2 | insulin receptor substrate 2 | -0.0254875 |
| CLDN4 | claudin 4 | -0.0254173 |
| PGK1 | phosphoglycerate kinase 1 | -0.0253268 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.024865 |
| STK17B | serine/threonine kinase 17b | -0.024661 |
| PFN1 | profilin 1 | -0.0245425 |
| S100A6 | S100 calcium binding protein A6 | -0.0244998 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0244404 |
| TMF1 | TATA element modulatory factor 1 | -0.0241978 |
| TAPBP | TAP binding protein (tapasin) | -0.0240942 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0238406 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0237107 |
| PLAU | plasminogen activator, urokinase | -0.0235424 |
| LIMA1 | LIM domain and actin binding 1 | -0.0234879 |
| SRP54 | signal recognition particle 54kDa | -0.0233548 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0232505 |
| RBM25 | RNA binding motif protein 25 | -0.0230559 |
| RUNX1 | runt-related transcription factor 1 | -0.0229485 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0227171 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0226198 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0224573 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.0223069 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0220249 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0219717 |
| RPS19 | ribosomal protein S19 | -0.0218884 |
| ENO1 | enolase 1, (alpha) | -0.0218237 |
| NFIB | nuclear factor I/B | -0.0218034 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0217233 |
| KLHL24 | kelch-like family member 24 | -0.0216642 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0214569 |
