| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DLC1 | DLC1 Rho GTPase activating protein | 0.116294 |
| ZNF438 | zinc finger protein 438 | 0.0983657 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0692991 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0644724 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.061973 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0599067 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0570799 |
| PGK1 | phosphoglycerate kinase 1 | 0.0524028 |
| RPL35A | ribosomal protein L35a | 0.0518816 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0517771 |
| BNC2 | basonuclin 2 | 0.0509187 |
| RPLP0 | ribosomal protein, large, P0 | 0.0499867 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0477377 |
| FRMD4A | FERM domain containing 4A | 0.0436742 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0423383 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0408975 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0392882 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0392023 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0383154 |
| STC1 | stanniocalcin 1 | 0.0380221 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 0.0380079 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0378835 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0374081 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0370413 |
| RAD51B | RAD51 paralog B | 0.0357203 |
| PCBP2 | poly(rC) binding protein 2 | 0.0353381 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0347595 |
| CALD1 | caldesmon 1 | 0.0320953 |
| HMGA1 | high mobility group AT-hook 1 | 0.0316037 |
| TMSB10 | thymosin beta 10 | 0.0313619 |
| MSI2 | musashi RNA-binding protein 2 | 0.0304227 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0290974 |
| ENO1 | enolase 1, (alpha) | 0.0287734 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 0.0285893 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0283875 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.028133 |
| FMNL2 | formin-like 2 | 0.0279757 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0278661 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0278311 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0276927 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0275705 |
| HDAC9 | histone deacetylase 9 | 0.0274613 |
| NAV3 | neuron navigator 3 | 0.02737 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0266549 |
| POU2F1 | POU class 2 homeobox 1 | 0.026122 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0255673 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0255361 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0253791 |
| LDHA | lactate dehydrogenase A | 0.0253586 |
| CBX3 | chromobox homolog 3 | 0.0252248 |
| ATP13A3 | ATPase type 13A3 | 0.0250739 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0246515 |
| S100A2 | S100 calcium binding protein A2 | 0.0244904 |
| SRPK2 | SRSF protein kinase 2 | 0.0243641 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0241464 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0238807 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0236174 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0235791 |
| ZNF292 | zinc finger protein 292 | 0.0235684 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.02356 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0230096 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0226696 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0224072 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.021984 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0219628 |
| FLNB | filamin B, beta | 0.0219611 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0219383 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0217441 |
| TPM4 | tropomyosin 4 | 0.0217099 |
| RPS24 | ribosomal protein S24 | 0.0216684 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0216331 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0213262 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0212621 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0209641 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0209211 |
| RAB3IP | RAB3A interacting protein | 0.0208003 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0207766 |
| XPO1 | exportin 1 | 0.0207601 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.020735 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0204674 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0201391 |
| HMGA2 | high mobility group AT-hook 2 | 0.0198809 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0195859 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0195653 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0195606 |
| CAST | calpastatin | 0.0192706 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.01919 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0191285 |
| CEP44 | centrosomal protein 44kDa | 0.0190818 |
| TENM3 | teneurin transmembrane protein 3 | 0.0189102 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0188365 |
| RPS12 | ribosomal protein S12 | 0.0187966 |
| HMGB2 | high mobility group box 2 | 0.0187928 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0186614 |
| CD2AP | CD2-associated protein | 0.0184392 |
| RPL30 | ribosomal protein L30 | 0.0184099 |
| DIAPH3 | diaphanous-related formin 3 | 0.0183266 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0182749 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0182189 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0179851 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | -0.166234 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0891148 |
| JMJD1C | jumonji domain containing 1C | -0.0828246 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0825808 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0761688 |
| RPS2 | ribosomal protein S2 | -0.0598676 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.058989 |
| USP34 | ubiquitin specific peptidase 34 | -0.0578042 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0543051 |
| CAPRIN2 | caprin family member 2 | -0.0540821 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0499943 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0473958 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0473096 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0462902 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0452679 |
| RPL3 | ribosomal protein L3 | -0.0425918 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0423889 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0403026 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0399686 |
| TXNRD1 | thioredoxin reductase 1 | -0.0390224 |
| TMF1 | TATA element modulatory factor 1 | -0.0389047 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0388294 |
| RPL7 | ribosomal protein L7 | -0.0375689 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0359789 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0351372 |
| RBM39 | RNA binding motif protein 39 | -0.034993 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0347498 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0343418 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0335769 |
| SGMS2 | sphingomyelin synthase 2 | -0.0334432 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0326526 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0320863 |
| STK4 | serine/threonine kinase 4 | -0.0319995 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0318946 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0317306 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0311672 |
| UPP1 | uridine phosphorylase 1 | -0.0309752 |
| CTTNBP2NL | CTTNBP2 N-terminal like | -0.0307941 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0305952 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0305833 |
| BRD2 | bromodomain containing 2 | -0.0302094 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0301392 |
| RECQL | RecQ helicase-like | -0.0300789 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0299155 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0298462 |
| WASL | Wiskott-Aldrich syndrome-like | -0.0288528 |
| TMEM156 | transmembrane protein 156 | -0.0286309 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0284539 |
| TPD52 | tumor protein D52 | -0.0282574 |
| RPL7A | ribosomal protein L7a | -0.0274487 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0273252 |
| CALU | calumenin | -0.0260394 |
| RPS18 | ribosomal protein S18 | -0.0259008 |
| STRN | striatin, calmodulin binding protein | -0.0255799 |
| PRELID2 | PRELI domain containing 2 | -0.025482 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0254405 |
| CORO1C | coronin, actin binding protein, 1C | -0.0252758 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0251556 |
| DSG2 | desmoglein 2 | -0.0250689 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.024985 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0249445 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0247819 |
| MCL1 | myeloid cell leukemia 1 | -0.0246392 |
| NKTR | natural killer cell triggering receptor | -0.0245751 |
| SPAG9 | sperm associated antigen 9 | -0.0238342 |
| ARFGEF3 | ARFGEF family member 3 | -0.0237009 |
| UBC | ubiquitin C | -0.0235908 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0235303 |
| ATM | ATM serine/threonine kinase | -0.0234764 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0232596 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0232001 |
| CLTC | clathrin, heavy chain (Hc) | -0.0231669 |
| MYO9B | myosin IXB | -0.0231299 |
| HDLBP | high density lipoprotein binding protein | -0.0231189 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.0228425 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0227444 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0225507 |
| MYO9A | myosin IXA | -0.0223573 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0222931 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0222813 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0220849 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0219864 |
| SON | SON DNA binding protein | -0.0219175 |
| RASA2 | RAS p21 protein activator 2 | -0.0218672 |
| BRD4 | bromodomain containing 4 | -0.0218379 |
| ADAR | adenosine deaminase, RNA-specific | -0.0218265 |
| TUT7 | terminal uridylyl transferase 7 | -0.0218162 |
| ZNF706 | zinc finger protein 706 | -0.0216499 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -0.0211153 |
| H1-4 | H1.4 linker histone, cluster member | -0.0210344 |
| RNF216 | ring finger protein 216 | -0.0209996 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0209551 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | -0.0208973 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0207998 |
| SETX | senataxin | -0.0207249 |
| STXBP1 | syntaxin binding protein 1 | -0.0206464 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0206419 |
| EXOC6B | exocyst complex component 6B | -0.0205931 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | -0.0204878 |
| WDR26 | WD repeat domain 26 | -0.0203896 |
