| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.0558731 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.026549 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0247437 |
| PCBP2 | poly(rC) binding protein 2 | 0.0243313 |
| MATR3 | matrin 3 | 0.0236044 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0188969 |
| CCNL1 | cyclin L1 | 0.0178257 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.017489 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0174104 |
| ZNF292 | zinc finger protein 292 | 0.0170704 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0162774 |
| BBX | bobby sox homolog (Drosophila) | 0.0161701 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0157121 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0156931 |
| ECT2 | epithelial cell transforming 2 | 0.0156731 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0156096 |
| CDK19 | cyclin-dependent kinase 19 | 0.015583 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.015468 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0154045 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0149898 |
| USP3 | ubiquitin specific peptidase 3 | 0.0145995 |
| SETD5 | SET domain containing 5 | 0.0143476 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.014052 |
| TFG | TRK-fused gene | 0.0139744 |
| TGM2 | transglutaminase 2 | 0.0139013 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0132774 |
| MSN | moesin | 0.0128129 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0127527 |
| MED13L | mediator complex subunit 13-like | 0.0124276 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0123598 |
| ZNF451 | zinc finger protein 451 | 0.0123275 |
| PHIP | pleckstrin homology domain interacting protein | 0.0122763 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0121822 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0121756 |
| CD109 | CD109 molecule | 0.0120894 |
| SET | SET nuclear proto-oncogene | 0.0120076 |
| RPL28 | ribosomal protein L28 | 0.0119077 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.0118924 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0118538 |
| WDR43 | WD repeat domain 43 | 0.0118399 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0117681 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0117562 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0117215 |
| MTDH | metadherin | 0.0117042 |
| TMF1 | TATA element modulatory factor 1 | 0.0114229 |
| HMGA1 | high mobility group AT-hook 1 | 0.0112474 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0112237 |
| RPL9 | ribosomal protein L9 | 0.0112133 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0110915 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0108982 |
| RPLP2 | ribosomal protein, large, P2 | 0.010822 |
| FOXP1 | forkhead box P1 | 0.0106409 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0105728 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0105231 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0104287 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0104085 |
| NEK7 | NIMA-related kinase 7 | 0.0103895 |
| RHEB | Ras homolog enriched in brain | 0.01038 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0103696 |
| FOSL1 | FOS-like antigen 1 | 0.0101296 |
| CD47 | CD47 molecule | 0.0100995 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0100112 |
| RBM25 | RNA binding motif protein 25 | 0.00997437 |
| FAR1 | fatty acyl CoA reductase 1 | 0.00996386 |
| CENPF | centromere protein F, 350/400kDa | 0.00994724 |
| RPL23 | ribosomal protein L23 | 0.00990486 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0098518 |
| NUF2 | NUF2, NDC80 kinetochore complex component | 0.00979238 |
| RPL35A | ribosomal protein L35a | 0.00960421 |
| ZNF638 | zinc finger protein 638 | 0.00956316 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00949255 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.00938033 |
| RPS25 | ribosomal protein S25 | 0.00934992 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.00932381 |
| FMR1 | fragile X mental retardation 1 | 0.00931816 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.00929797 |
| RYK | receptor-like tyrosine kinase | 0.00929267 |
| ERBIN | erbb2 interacting protein | 0.00927711 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.00916776 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00915049 |
| IPO7 | importin 7 | 0.00914577 |
| TCP1 | t-complex 1 | 0.00911679 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0090958 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.00906159 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00905537 |
| SPPL3 | signal peptide peptidase like 3 | 0.00897355 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.00892294 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.00890844 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.00886231 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.00883109 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.00880897 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.00880487 |
| RPS19 | ribosomal protein S19 | 0.00879997 |
| ZNF148 | zinc finger protein 148 | 0.00879745 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.00879475 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00877075 |
| ZNF207 | zinc finger protein 207 | 0.00873792 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.00870066 |
| UBA5 | ubiquitin-like modifier activating enzyme 5 | 0.00864084 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.00863785 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.266997 |
| VIM | vimentin | -0.214446 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.134932 |
| COL1A2 | collagen, type I, alpha 2 | -0.0973759 |
| NDRG1 | N-myc downstream regulated 1 | -0.0897008 |
| FRMD4A | FERM domain containing 4A | -0.0765765 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0654831 |
| ANXA2 | annexin A2 | -0.0585064 |
| FAM20C | family with sequence similarity 20, member C | -0.0580977 |
| LOXL2 | lysyl oxidase-like 2 | -0.0578279 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0573452 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0561569 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0557706 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.051455 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0492309 |
| CD44 | CD44 molecule (Indian blood group) | -0.0452876 |
| COL5A1 | collagen, type V, alpha 1 | -0.0450704 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0425878 |
| SP100 | SP100 nuclear antigen | -0.0415345 |
| RRBP1 | ribosome binding protein 1 | -0.041415 |
| COL1A1 | collagen, type I, alpha 1 | -0.0405543 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0396643 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0374631 |
| TPM1 | tropomyosin 1 (alpha) | -0.0360131 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0358066 |
| CALU | calumenin | -0.0353267 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0352603 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0344207 |
| INHBA | inhibin, beta A | -0.0333546 |
| GLIS3 | GLIS family zinc finger 3 | -0.0328849 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0327974 |
| TNNC1 | troponin C type 1 (slow) | -0.0326508 |
| ENO1 | enolase 1, (alpha) | -0.0324562 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0317851 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0311586 |
| TMEM178B | transmembrane protein 178B | -0.0310954 |
| LDHA | lactate dehydrogenase A | -0.0308088 |
| HM13 | histocompatibility (minor) 13 | -0.0306702 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0305322 |
| MX2 | MX dynamin-like GTPase 2 | -0.0305196 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.029802 |
| H1-0 | H1.0 linker histone | -0.0294531 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0289567 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0288744 |
| TNS3 | tensin 3 | -0.0287883 |
| NRP1 | neuropilin 1 | -0.0285612 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0285586 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0284976 |
| NAV1 | neuron navigator 1 | -0.0284492 |
| CAVIN1 | caveolae associated protein 1 | -0.0277016 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0276846 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0268813 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0267679 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0266468 |
| HLA-C | major histocompatibility complex, class I, C | -0.0265851 |
| PLSCR1 | phospholipid scramblase 1 | -0.026241 |
| HLA-B | major histocompatibility complex, class I, B | -0.0261593 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0257046 |
| HDLBP | high density lipoprotein binding protein | -0.0252516 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0251627 |
| PGK1 | phosphoglycerate kinase 1 | -0.0249096 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0248524 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0248205 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0241986 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0241159 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.024015 |
| ATM | ATM serine/threonine kinase | -0.0234654 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0231021 |
| ARF4 | ADP-ribosylation factor 4 | -0.0230193 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0230103 |
| RUNX1 | runt-related transcription factor 1 | -0.0229685 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0228412 |
| CDH13 | cadherin 13 | -0.0226939 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0224909 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.022436 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0223763 |
| ATXN1 | ataxin 1 | -0.0223038 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0221197 |
| SVIL | supervillin | -0.022063 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0219135 |
| SEC24D | SEC24 family member D | -0.0218936 |
| MYO1E | myosin IE | -0.0218599 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0218247 |
| EGR1 | early growth response 1 | -0.0217794 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0216432 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0216314 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0214782 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0213004 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0212012 |
| PDE10A | phosphodiesterase 10A | -0.0211926 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0207905 |
| B2M | beta-2-microglobulin | -0.0206901 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0206014 |
| OSMR | oncostatin M receptor | -0.0205609 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0204161 |
| FLNB | filamin B, beta | -0.0203815 |
| SQSTM1 | sequestosome 1 | -0.0202667 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0201344 |
| HMGA2 | high mobility group AT-hook 2 | -0.0200971 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0200714 |
