| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Benproperine (phosphate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LSAMP | limbic system-associated membrane protein | 0.163877 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.13649 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.126286 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.124015 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.10154 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0829255 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0801873 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0755362 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0714375 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0704864 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0701521 |
| MSI2 | musashi RNA-binding protein 2 | 0.0693894 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0683432 |
| SPAG9 | sperm associated antigen 9 | 0.0683091 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0678533 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.063516 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0622804 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0585543 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0583713 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | 0.0579324 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0560784 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0557193 |
| FMN1 | formin 1 | 0.0554084 |
| RTN4 | reticulon 4 | 0.0546183 |
| USP3 | ubiquitin specific peptidase 3 | 0.05396 |
| KAZN | kazrin, periplakin interacting protein | 0.0533589 |
| CANX | calnexin | 0.0531989 |
| ZNF292 | zinc finger protein 292 | 0.0529779 |
| RBM39 | RNA binding motif protein 39 | 0.0518095 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0514013 |
| ATP13A3 | ATPase type 13A3 | 0.051176 |
| GOLGA4 | golgin A4 | 0.0502659 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0491887 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0484854 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0450133 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0443423 |
| SQSTM1 | sequestosome 1 | 0.0442783 |
| CDC73 | cell division cycle 73 | 0.0439047 |
| TXNRD1 | thioredoxin reductase 1 | 0.043212 |
| CLINT1 | clathrin interactor 1 | 0.0420615 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0413561 |
| TRIM33 | tripartite motif containing 33 | 0.0411061 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.040421 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0404112 |
| SFTPA2 | surfactant protein A2 | 0.038835 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0385521 |
| NGLY1 | N-glycanase 1 | 0.0383501 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0382446 |
| JMJD1C | jumonji domain containing 1C | 0.038242 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0378744 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0377213 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0377052 |
| LDHA | lactate dehydrogenase A | 0.0370922 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0369617 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.036425 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0362892 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0361436 |
| MATR3 | matrin 3 | 0.03609 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0355202 |
| ABI1 | abl-interactor 1 | 0.0355162 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0351575 |
| COPA | coatomer protein complex, subunit alpha | 0.0351382 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0350062 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0348218 |
| PEX5L | peroxisomal biogenesis factor 5-like | 0.0346176 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0344202 |
| TFRC | transferrin receptor | 0.0341714 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0340538 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0338631 |
| TFG | TRK-fused gene | 0.0334822 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0334685 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0334083 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0333885 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0332003 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.033179 |
| TRIQK | triple QxxK/R motif containing | 0.032896 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0322291 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0322152 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0322138 |
| PTMA | prothymosin, alpha | 0.031767 |
| FMNL2 | formin-like 2 | 0.0317466 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0317285 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0311099 |
| TNPO1 | transportin 1 | 0.0310579 |
| INSIG2 | insulin induced gene 2 | 0.0309213 |
| PCNX1 | pecanex 1 | 0.0308392 |
| NCKAP1 | NCK-associated protein 1 | 0.0307639 |
| SERINC1 | serine incorporator 1 | 0.0301918 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0301474 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.030053 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0298956 |
| RHOA | ras homolog family member A | 0.0298442 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0294116 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.029297 |
| QKI | QKI, KH domain containing, RNA binding | 0.0292571 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0289467 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0289363 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0287867 |
| MAP4 | microtubule-associated protein 4 | 0.0287131 |
| PMEL | premelanosome protein | 0.028713 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.162216 |
| NLGN1 | neuroligin 1 | -0.108495 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105206 |
| TMSB10 | thymosin beta 10 | -0.0631292 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0620343 |
| PRELID2 | PRELI domain containing 2 | -0.0572435 |
| NDRG1 | N-myc downstream regulated 1 | -0.0557739 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0532375 |
| FRMD4A | FERM domain containing 4A | -0.0525364 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0517911 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.048194 |
| FTL | ferritin, light polypeptide | -0.0470034 |
| POTEF | POTE ankyrin domain family, member F | -0.046264 |
| MT1X | metallothionein 1X | -0.0450643 |
| BPTF | bromodomain PHD finger transcription factor | -0.0447477 |
| ANGPTL4 | angiopoietin-like 4 | -0.0413799 |
| CCND1 | cyclin D1 | -0.0411025 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.041008 |
| FLNB | filamin B, beta | -0.0384189 |
| ACTN4 | actinin, alpha 4 | -0.0382927 |
| VIM | vimentin | -0.038184 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0380758 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0377708 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0374637 |
| RNF213 | ring finger protein 213 | -0.0359021 |
| RAD51B | RAD51 paralog B | -0.0351267 |
| TENM1 | teneurin transmembrane protein 1 | -0.0346495 |
| PLAT | plasminogen activator, tissue | -0.0330269 |
| EFNA5 | ephrin-A5 | -0.0329878 |
| CHD6 | chromodomain helicase DNA binding protein 6 | -0.0329364 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0321912 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0319635 |
| SMAD3 | SMAD family member 3 | -0.0318297 |
| NAV2 | neuron navigator 2 | -0.0313826 |
| RPS6 | ribosomal protein S6 | -0.0313062 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0311453 |
| RPLP1 | ribosomal protein, large, P1 | -0.0309171 |
| LAMB1 | laminin, beta 1 | -0.0307224 |
| CENPF | centromere protein F, 350/400kDa | -0.0306427 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.030617 |
| KIAA1549L | KIAA1549-like | -0.0306007 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.0305279 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0303759 |
| FLNA | filamin A, alpha | -0.030012 |
| TMEM51 | transmembrane protein 51 | -0.0298648 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0297938 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0296789 |
| HDAC4 | histone deacetylase 4 | -0.0295928 |
| ASPH | aspartate beta-hydroxylase | -0.0295368 |
| TGFA | transforming growth factor, alpha | -0.0281535 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.027897 |
| RPL28 | ribosomal protein L28 | -0.0278445 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.027729 |
| ACTN1 | actinin, alpha 1 | -0.0272605 |
| ENO1 | enolase 1, (alpha) | -0.0270671 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0270323 |
| TOB2 | transducer of ERBB2, 2 | -0.0269103 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0267244 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0266009 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0264237 |
| SEPTIN9 | septin 9 | -0.0263451 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0262791 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0262602 |
| HMGA1 | high mobility group AT-hook 1 | -0.025987 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0257805 |
| TP63 | tumor protein p63 | -0.0253727 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0247323 |
| FGGY | FGGY carbohydrate kinase domain containing | -0.0246757 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0245594 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0243704 |
| MEIS2 | Meis homeobox 2 | -0.0242209 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.023973 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0239715 |
| RPS19 | ribosomal protein S19 | -0.0239605 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0238144 |
| RPS21 | ribosomal protein S21 | -0.0236205 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0233617 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0231859 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0231495 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0230983 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0230961 |
| SUMF1 | sulfatase modifying factor 1 | -0.0228011 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0227706 |
| SOX10 | SRY (sex determining region Y)-box 10 | -0.022647 |
| RPL27A | ribosomal protein L27a | -0.0225183 |
| ACTG1 | actin gamma 1 | -0.0224081 |
| FAM78B | family with sequence similarity 78, member B | -0.0223063 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0222822 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0222211 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | -0.0219795 |
| RPS23 | ribosomal protein S23 | -0.0219211 |
| EXOC4 | exocyst complex component 4 | -0.02185 |
| EP400 | E1A binding protein p400 | -0.021805 |
| SHC4 | SHC (Src homology 2 domain containing) family, member 4 | -0.0217602 |
| SSH1 | slingshot protein phosphatase 1 | -0.0216586 |
| SH3PXD2B | SH3 and PX domains 2B | -0.0214425 |
| FRYL | FRY-like | -0.0214299 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0214073 |
| PDE10A | phosphodiesterase 10A | -0.0213134 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0212833 |
