Benproperine (phosphate)_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Benproperine (phosphate) perturbation in SNU-1 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Benproperine (phosphate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
QKI QKI, KH domain containing, RNA binding 0.060295
ZNF292 zinc finger protein 292 0.0588815
CAMTA1 calmodulin binding transcription activator 1 0.058822
ECT2 epithelial cell transforming 2 0.0573826
SOX6 SRY (sex determining region Y)-box 6 0.0558296
ZFAND3 zinc finger, AN1-type domain 3 0.0481425
DSCAM Down syndrome cell adhesion molecule 0.0437527
TFG TRK-fused gene 0.0394699
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.03904
NAMPT nicotinamide phosphoribosyltransferase 0.0389549
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0383791
MED13 mediator complex subunit 13 0.0382303
PUM2 pumilio RNA-binding family member 2 0.0380176
FLNB filamin B, beta 0.0364903
UBA6 ubiquitin-like modifier activating enzyme 6 0.0360445
SRPK2 SRSF protein kinase 2 0.0359629
NUP58 nucleoporin 58 0.0354753
ZCCHC7 zinc finger, CCHC domain containing 7 0.0345441
TBC1D5 TBC1 domain family, member 5 0.0333099
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.0329586
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 0.0323848
GOLGA4 golgin A4 0.0321917
ELOVL5 ELOVL fatty acid elongase 5 0.0319846
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.0318532
METTL15 methyltransferase like 15 0.0305041
RBM39 RNA binding motif protein 39 0.0304693
TBC1D22A TBC1 domain family, member 22A 0.0301278
USP34 ubiquitin specific peptidase 34 0.0298238
CHD1 chromodomain helicase DNA binding protein 1 0.0297803
GSK3B glycogen synthase kinase 3 beta 0.029434
MBD5 methyl-CpG binding domain protein 5 0.0283216
TMEM41B transmembrane protein 41B 0.0277945
RCOR1 REST corepressor 1 0.0270501
CNOT4 CCR4-NOT transcription complex, subunit 4 0.0268647
BLTP1 bridge-like lipid transfer protein family member 1 0.0267693
CCNL1 cyclin L1 0.0267461
ZFC3H1 zinc finger, C3H1-type containing 0.0266402
LRPPRC leucine-rich pentatricopeptide repeat containing 0.0266135
NBAS neuroblastoma amplified sequence 0.0264925
PDE4D phosphodiesterase 4D, cAMP-specific 0.0263652
PDGFC platelet derived growth factor C 0.0257268
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.0255299
PTBP2 polypyrimidine tract binding protein 2 0.0255265
CD47 CD47 molecule 0.0252335
NF1 neurofibromin 1 0.0248273
CKAP5 cytoskeleton associated protein 5 0.0247543
SLMAP sarcolemma associated protein 0.0246531
KMT2C lysine (K)-specific methyltransferase 2C 0.024295
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.0242011
GARS1 glycyl-tRNA synthetase 1 0.0241425
DCAF6 DDB1 and CUL4 associated factor 6 0.0239271
COPA coatomer protein complex, subunit alpha 0.0237746
POU2F1 POU class 2 homeobox 1 0.0237236
SLC38A2 solute carrier family 38, member 2 0.0236584
KDM5A lysine (K)-specific demethylase 5A 0.0236297
GOLGA2 golgin A2 0.0234461
NCEH1 neutral cholesterol ester hydrolase 1 0.0234113
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.0232758
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.0231909
SFPQ splicing factor proline/glutamine-rich 0.0228681
AGFG1 ArfGAP with FG repeats 1 0.0228461
SNX9 sorting nexin 9 0.0228001
PICALM phosphatidylinositol binding clathrin assembly protein 0.0226468
CUL3 cullin 3 0.0226303
USP9X ubiquitin specific peptidase 9, X-linked 0.0225479
SNX13 sorting nexin 13 0.0225098
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0223507
ASXL1 additional sex combs like transcriptional regulator 1 0.0221937
FNIP1 folliculin interacting protein 1 0.0221545
LPP LIM domain containing preferred translocation partner in lipoma 0.0220898
ZNF644 zinc finger protein 644 0.0220248
PUM1 pumilio RNA-binding family member 1 0.0219074
CNOT1 CCR4-NOT transcription complex, subunit 1 0.0217867
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 0.0217855
TAS2R14 taste receptor, type 2, member 14 0.0215751
CEP95 centrosomal protein 95kDa 0.0215442
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 0.0215327
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 0.0214471
FXR1 fragile X mental retardation, autosomal homolog 1 0.0213477
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0213466
BTBD9 BTB (POZ) domain containing 9 0.0213455
ZC3H11A zinc finger CCCH-type containing 11A 0.0212684
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.0208487
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.0205214
FUBP1 far upstream element (FUSE) binding protein 1 0.0204796
CCDC88A coiled-coil domain containing 88A 0.0204619
MAPK6 mitogen-activated protein kinase 6 0.0203752
CREBRF CREB3 regulatory factor 0.0201963
BRWD1 bromodomain and WD repeat domain containing 1 0.020188
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.02007
TASOR2 transcription activation suppressor family member 2 0.0199763
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 0.0199668
ZBTB20 zinc finger and BTB domain containing 20 0.0198719
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.0198652
DLG1 discs, large homolog 1 (Drosophila) 0.0198369
LMAN1 lectin, mannose-binding, 1 0.019788
ITCH itchy E3 ubiquitin protein ligase 0.0197619
LCORL ligand dependent nuclear receptor corepressor-like 0.0197005
ANKRD17 ankyrin repeat domain 17 0.019699
TJP1 tight junction protein 1 0.0196623

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.224155
PTMA prothymosin, alpha -0.166837
RPS6 ribosomal protein S6 -0.130401
TPT1 tumor protein, translationally-controlled 1 -0.123064
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -0.113674
BMP10 bone morphogenetic protein 10 -0.0888062
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0825289
RPL35A ribosomal protein L35a -0.0811436
RPS8 ribosomal protein S8 -0.0781754
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0776028
ACTG1 actin gamma 1 -0.0701065
EEF2 eukaryotic translation elongation factor 2 -0.0693892
AHNAK AHNAK nucleoprotein -0.0686292
PDE4B phosphodiesterase 4B, cAMP-specific -0.0648845
VCL vinculin -0.0625197
ARL4C ADP-ribosylation factor-like 4C -0.0621717
RPL31 ribosomal protein L31 -0.0611603
RPLP1 ribosomal protein, large, P1 -0.0597697
RPL12 ribosomal protein L12 -0.0588123
RPL30 ribosomal protein L30 -0.057646
RPLP0 ribosomal protein, large, P0 -0.0562568
TM4SF1 transmembrane 4 L six family member 1 -0.0561927
ANXA1 annexin A1 -0.0555862
RPL19 ribosomal protein L19 -0.054883
RPL7A ribosomal protein L7a -0.0547531
RPLP2 ribosomal protein, large, P2 -0.0546553
RPS13 ribosomal protein S13 -0.0544795
RPS27A ribosomal protein S27a -0.0517539
RPS12 ribosomal protein S12 -0.0499454
RPL34 ribosomal protein L34 -0.0485267
RACK1 receptor for activated C kinase 1 -0.0485063
RPL11 ribosomal protein L11 -0.0480402
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.047269
S100A4 S100 calcium binding protein A4 -0.046824
PKM pyruvate kinase, muscle -0.0452313
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0451217
RPS25 ribosomal protein S25 -0.0448541
HSPB1 heat shock 27kDa protein 1 -0.0440196
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0433798
MYO5C myosin VC -0.0429932
RPL37A ribosomal protein L37a -0.0427259
S100A6 S100 calcium binding protein A6 -0.0423241
ENO1 enolase 1, (alpha) -0.0421024
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.0411839
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0401234
TMSB10 thymosin beta 10 -0.0398638
LOC112694756 uncharaterized LOC112694756 -0.0397841
RPS16 ribosomal protein S16 -0.0396522
KPNB1 karyopherin (importin) beta 1 -0.0388802
PGK1 phosphoglycerate kinase 1 -0.0387676
RPL27A ribosomal protein L27a -0.0385781
SPATS2L spermatogenesis associated, serine-rich 2-like -0.0383274
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.0371307
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0361333
FOXP1 forkhead box P1 -0.0360513
RSL1D1 ribosomal L1 domain containing 1 -0.0359327
RPS3 ribosomal protein S3 -0.0357309
EFNA5 ephrin-A5 -0.0356573
FTL ferritin, light polypeptide -0.035654
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0354364
RPL9 ribosomal protein L9 -0.0353214
DUSP4 dual specificity phosphatase 4 -0.0352038
CAMKMT calmodulin-lysine N-methyltransferase -0.0348744
CCND1 cyclin D1 -0.0347554
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0347124
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.034052
RPL13A ribosomal protein L13a -0.0338683
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -0.0334974
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0334163
MYOF myoferlin -0.033046
GSE1 Gse1 coiled-coil protein -0.032983
DUSP6 dual specificity phosphatase 6 -0.032809
RPL5 ribosomal protein L5 -0.032499
S100A10 S100 calcium binding protein A10 -0.0323851
MYL12B myosin, light chain 12B, regulatory -0.0321909
BMP2K BMP2 inducible kinase -0.0320167
S100A9 S100 calcium binding protein A9 -0.0311093
EIF4A2 eukaryotic translation initiation factor 4A2 -0.0310473
RPL26 ribosomal protein L26 -0.0306414
RPL8 ribosomal protein L8 -0.0295326
SDK1 sidekick cell adhesion molecule 1 -0.0294628
TPM4 tropomyosin 4 -0.029211
WSB1 WD repeat and SOCS box containing 1 -0.0290633
RPL36 ribosomal protein L36 -0.0290515
HSPH1 heat shock 105kDa/110kDa protein 1 -0.0278567
EBNA1BP2 EBNA1 binding protein 2 -0.0277592
RPS19 ribosomal protein S19 -0.0274419
TPI1 triosephosphate isomerase 1 -0.0273212
LDHB lactate dehydrogenase B -0.027303
RPL38 ribosomal protein L38 -0.0272982
ZNF638 zinc finger protein 638 -0.0272915
ENOX1 ecto-NOX disulfide-thiol exchanger 1 -0.0271686
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0271318
UNC13A unc-13 homolog A (C. elegans) -0.0268771
RPS14 ribosomal protein S14 -0.0267675
CRPPA CDP-L-ribitol pyrophosphorylase A -0.0267583
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0266971
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0266214
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0265783
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0260575