| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.112997 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0891706 |
| CDH13 | cadherin 13 | 0.0859951 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0836008 |
| NAV1 | neuron navigator 1 | 0.0635298 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0591556 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0572754 |
| NRXN3 | neurexin 3 | 0.0566283 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0499044 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0459366 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0451594 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0444032 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0439549 |
| COL1A2 | collagen, type I, alpha 2 | 0.0429472 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0425189 |
| ERBIN | erbb2 interacting protein | 0.0359307 |
| PARD3 | par-3 family cell polarity regulator | 0.0358981 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0356096 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0350399 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0335194 |
| SYNPO | synaptopodin | 0.0320099 |
| HMGA2 | high mobility group AT-hook 2 | 0.0317191 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0315531 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0312384 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0310867 |
| EHBP1 | EH domain binding protein 1 | 0.0307173 |
| RUNX1 | runt-related transcription factor 1 | 0.0307145 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0306729 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.029796 |
| FLNB | filamin B, beta | 0.0294795 |
| FN1 | fibronectin 1 | 0.0294751 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0293487 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.029269 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0288431 |
| CMIP | c-Maf inducing protein | 0.0287679 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0283095 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0281105 |
| ZNF609 | zinc finger protein 609 | 0.028068 |
| FRMD5 | FERM domain containing 5 | 0.0271448 |
| SBF2 | SET binding factor 2 | 0.0265214 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0265173 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.026253 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.026178 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.026109 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0261077 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0259578 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0255178 |
| TLK1 | tousled-like kinase 1 | 0.025513 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0254656 |
| PRSS23 | protease, serine, 23 | 0.0250517 |
| PRKCA | protein kinase C, alpha | 0.0249774 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0247587 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0245723 |
| AK1 | adenylate kinase 1 | 0.024206 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0241904 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0241379 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0239868 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0238884 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0238828 |
| SON | SON DNA binding protein | 0.0238611 |
| CLASP1 | cytoplasmic linker associated protein 1 | 0.0238045 |
| WDR43 | WD repeat domain 43 | 0.0235567 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0230737 |
| FAM13A | family with sequence similarity 13, member A | 0.0229654 |
| COL5A2 | collagen, type V, alpha 2 | 0.0228685 |
| ASPH | aspartate beta-hydroxylase | 0.022789 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0227004 |
| DENND4A | DENN/MADD domain containing 4A | 0.0222115 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0221971 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.022035 |
| SUMO1 | small ubiquitin-like modifier 1 | 0.021924 |
| OSMR | oncostatin M receptor | 0.0217899 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0215375 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0214416 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0214383 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0213485 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0213016 |
| CDK17 | cyclin-dependent kinase 17 | 0.0210864 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0208361 |
| UBE3C | ubiquitin protein ligase E3C | 0.0208025 |
| RAI14 | retinoic acid induced 14 | 0.0206115 |
| DIAPH2 | diaphanous-related formin 2 | 0.0205688 |
| COL1A1 | collagen, type I, alpha 1 | 0.0202942 |
| G0S2 | G0/G1 switch 2 | 0.0202035 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0200819 |
| USP34 | ubiquitin specific peptidase 34 | 0.0199739 |
| LAMB3 | laminin, beta 3 | 0.0199463 |
| GLIS3 | GLIS family zinc finger 3 | 0.0199028 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0199008 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0198647 |
| CDK13 | cyclin-dependent kinase 13 | 0.0196926 |
| CLMP | CXADR-like membrane protein | 0.0196907 |
| WWOX | WW domain containing oxidoreductase | 0.0196378 |
| RPL5 | ribosomal protein L5 | 0.0196188 |
| PTGR1 | prostaglandin reductase 1 | 0.0196152 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0195765 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0194584 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0194171 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0192819 |
| BMERB1 | bMERB domain containing 1 | 0.0192332 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.0529168 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0502127 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0479084 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0456915 |
| HLA-B | major histocompatibility complex, class I, B | -0.0453899 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0412717 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0403298 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.03989 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0382181 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0374304 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0371269 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0349513 |
| VIM | vimentin | -0.0345256 |
| APP | amyloid beta (A4) precursor protein | -0.0344718 |
| H3-3B | H3.3 histone B | -0.0341475 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0333875 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.033372 |
| B2M | beta-2-microglobulin | -0.0333713 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0316345 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0315796 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0314613 |
| RNF24 | ring finger protein 24 | -0.0306091 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0305704 |
| ADM | adrenomedullin | -0.0305466 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0300064 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0295395 |
| RPL11 | ribosomal protein L11 | -0.029377 |
| RSF1 | remodeling and spacing factor 1 | -0.0289816 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0285887 |
| FAM13B | family with sequence similarity 13, member B | -0.0283707 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0281554 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0280491 |
| MATR3 | matrin 3 | -0.0279753 |
| PKM | pyruvate kinase, muscle | -0.0274497 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.027172 |
| THRAP3 | thyroid hormone receptor associated protein 3 | -0.0269719 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0265854 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0264402 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0260462 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0259455 |
| CTSB | cathepsin B | -0.0257298 |
| GOLGA4 | golgin A4 | -0.0250414 |
| HDLBP | high density lipoprotein binding protein | -0.02502 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0250155 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0247488 |
| CALU | calumenin | -0.024533 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0241239 |
| ZNF292 | zinc finger protein 292 | -0.0240359 |
| COG5 | component of oligomeric golgi complex 5 | -0.0238019 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0237069 |
| CD44 | CD44 molecule (Indian blood group) | -0.0236377 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0236134 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0235507 |
| SMAD3 | SMAD family member 3 | -0.0233374 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0233246 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0229904 |
| CCNI | cyclin I | -0.0228732 |
| RACK1 | receptor for activated C kinase 1 | -0.0227676 |
| MYOF | myoferlin | -0.022758 |
| SMYD3 | SET and MYND domain containing 3 | -0.0226699 |
| TXNIP | thioredoxin interacting protein | -0.0226043 |
| FBXO11 | F-box protein 11 | -0.0224828 |
| NDRG1 | N-myc downstream regulated 1 | -0.0223451 |
| TPM4 | tropomyosin 4 | -0.0222959 |
| PTMA | prothymosin, alpha | -0.0220803 |
| FTL | ferritin, light polypeptide | -0.0216338 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0215934 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0215143 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0214828 |
| SCAF8 | SR-related CTD-associated factor 8 | -0.0214234 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0213446 |
| MSN | moesin | -0.0212092 |
| MYLK | myosin light chain kinase | -0.0211201 |
| RPL26 | ribosomal protein L26 | -0.0208914 |
| RNF216 | ring finger protein 216 | -0.0208212 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0208091 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0205644 |
| RPS2 | ribosomal protein S2 | -0.020413 |
| TTC1 | tetratricopeptide repeat domain 1 | -0.0203077 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0200688 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.019867 |
| ZNF331 | zinc finger protein 331 | -0.0198085 |
| NOTCH2 | notch 2 | -0.0196449 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0196198 |
| ZNF395 | zinc finger protein 395 | -0.0194912 |
| USP24 | ubiquitin specific peptidase 24 | -0.0194231 |
| VEGFA | vascular endothelial growth factor A | -0.0193309 |
| FOXJ3 | forkhead box J3 | -0.0193254 |
| RPL37 | ribosomal protein L37 | -0.0193071 |
| ANLN | anillin, actin binding protein | -0.0192356 |
| MANBA | mannosidase, beta A, lysosomal | -0.019189 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0190816 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0190546 |
| TMEM263 | transmembrane protein 263 | -0.0190234 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.019008 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0189754 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0189684 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0189451 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0188504 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0186799 |
