| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUP58 | nucleoporin 58 | 0.0519679 |
| ECT2 | epithelial cell transforming 2 | 0.0402495 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0387344 |
| ZNF292 | zinc finger protein 292 | 0.0356488 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0321039 |
| RBM39 | RNA binding motif protein 39 | 0.0310013 |
| HELZ | helicase with zinc finger | 0.030922 |
| PCBP2 | poly(rC) binding protein 2 | 0.0308839 |
| TPX2 | TPX2, microtubule-associated | 0.0306226 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0302625 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0271706 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0269282 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0268484 |
| SETD5 | SET domain containing 5 | 0.0255478 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0255103 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0253406 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0251526 |
| TFG | TRK-fused gene | 0.023869 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0235668 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0230707 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0227641 |
| TXNRD1 | thioredoxin reductase 1 | 0.0223951 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0223823 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0220531 |
| QKI | QKI, KH domain containing, RNA binding | 0.0208677 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0207619 |
| TTK | TTK protein kinase | 0.0207365 |
| CRY1 | cryptochrome circadian clock 1 | 0.0203649 |
| CCNL1 | cyclin L1 | 0.0203613 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0203492 |
| WDR45B | WD repeat domain 45B | 0.0199287 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0199011 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.019783 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0194167 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.019313 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0192127 |
| ATP13A3 | ATPase type 13A3 | 0.0191513 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0190893 |
| CUL5 | cullin 5 | 0.0189547 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0188495 |
| ANLN | anillin, actin binding protein | 0.0188079 |
| COG5 | component of oligomeric golgi complex 5 | 0.0188044 |
| CUL3 | cullin 3 | 0.0187659 |
| DIAPH3 | diaphanous-related formin 3 | 0.0181927 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0181843 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0181408 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0181388 |
| SNX14 | sorting nexin 14 | 0.0180287 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0179025 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0178892 |
| PDS5B | PDS5 cohesin associated factor B | 0.0178729 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0178091 |
| CDK17 | cyclin-dependent kinase 17 | 0.0176294 |
| ETNK1 | ethanolamine kinase 1 | 0.0176224 |
| FANCI | Fanconi anemia, complementation group I | 0.017619 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.017553 |
| HMGB2 | high mobility group box 2 | 0.0173494 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0172271 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0170661 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0168552 |
| RAB22A | RAB22A, member RAS oncogene family | 0.016532 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0164332 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0164142 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0163185 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0162971 |
| CDK7 | cyclin-dependent kinase 7 | 0.0162389 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0161482 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0161093 |
| MATR3 | matrin 3 | 0.0160723 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0159216 |
| COG6 | component of oligomeric golgi complex 6 | 0.0159146 |
| CARD16 | caspase recruitment domain family, member 16 | 0.015897 |
| YAP1 | Yes-associated protein 1 | 0.0157996 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.01569 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0156711 |
| NOP58 | NOP58 ribonucleoprotein | 0.0155697 |
| NUF2 | NUF2, NDC80 kinetochore complex component | 0.0155481 |
| CDC27 | cell division cycle 27 | 0.0154765 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0152793 |
| TOP1 | topoisomerase (DNA) I | 0.015268 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0152138 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0151767 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0151758 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0151672 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0150861 |
| MPHOSPH9 | M-phase phosphoprotein 9 | 0.0149525 |
| CPNE8 | copine VIII | 0.014908 |
| NCKAP1 | NCK-associated protein 1 | 0.0148633 |
| MED13 | mediator complex subunit 13 | 0.0147531 |
| CEP250 | centrosomal protein 250kDa | 0.0146422 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.014598 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0145206 |
| OLA1 | Obg-like ATPase 1 | 0.0145007 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0144848 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0144614 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0144275 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0143779 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0143746 |
| INSIG2 | insulin induced gene 2 | 0.0143343 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0143327 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.236745 |
| VIM | vimentin | -0.118248 |
| TMSB10 | thymosin beta 10 | -0.0980904 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0975356 |
| CD44 | CD44 molecule (Indian blood group) | -0.0949396 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0877913 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.075883 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0708213 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0675108 |
| ANGPTL4 | angiopoietin-like 4 | -0.0662847 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0660831 |
| HMGA2 | high mobility group AT-hook 2 | -0.065392 |
| FMNL2 | formin-like 2 | -0.0642668 |
| LDHA | lactate dehydrogenase A | -0.0598136 |
| IGF2 | insulin-like growth factor 2 | -0.0537352 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0533678 |
| PTMA | prothymosin, alpha | -0.0530035 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0520199 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0516372 |
| ATM | ATM serine/threonine kinase | -0.0513677 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0510807 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0508037 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0504832 |
| PRSS23 | protease, serine, 23 | -0.0498644 |
| POTEF | POTE ankyrin domain family, member F | -0.0497228 |
| SVIL | supervillin | -0.0493196 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0491619 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0483849 |
| SLC38A2 | solute carrier family 38, member 2 | -0.048344 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0482782 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0471217 |
| SDC4 | syndecan 4 | -0.0465735 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0455401 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.04414 |
| GNAS | GNAS complex locus | -0.0429831 |
| MT2A | metallothionein 2A | -0.0423573 |
| DST | dystonin | -0.0409367 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0404227 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.040136 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0388587 |
| ATXN1 | ataxin 1 | -0.0388035 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0384174 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.038408 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0365978 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0364721 |
| RPL35A | ribosomal protein L35a | -0.0358984 |
| SMYD3 | SET and MYND domain containing 3 | -0.0356219 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0354434 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0354422 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0351191 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.035104 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0347879 |
| NDRG1 | N-myc downstream regulated 1 | -0.034374 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0340233 |
| PKM | pyruvate kinase, muscle | -0.0335613 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0332765 |
| ACTG1 | actin gamma 1 | -0.0332653 |
| OSMR | oncostatin M receptor | -0.0330679 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0330126 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0319872 |
| PRKCA | protein kinase C, alpha | -0.03154 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0315379 |
| RPLP1 | ribosomal protein, large, P1 | -0.0307891 |
| RIGI | RNA sensor RIG-I | -0.0305757 |
| ATG7 | autophagy related 7 | -0.0298619 |
| RAI14 | retinoic acid induced 14 | -0.0297207 |
| FMN1 | formin 1 | -0.029441 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0289654 |
| ANXA2 | annexin A2 | -0.0288372 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0287935 |
| VCL | vinculin | -0.0285578 |
| SQSTM1 | sequestosome 1 | -0.0283102 |
| FLNB | filamin B, beta | -0.0277535 |
| SEPTIN9 | septin 9 | -0.02769 |
| GPC6 | glypican 6 | -0.0276422 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0275421 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0272436 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0271731 |
| PRR16 | proline rich 16 | -0.0270875 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0268278 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0262701 |
| PYGL | phosphorylase, glycogen, liver | -0.0261956 |
| STXBP1 | syntaxin binding protein 1 | -0.0261898 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0261589 |
| PTK2 | protein tyrosine kinase 2 | -0.0260205 |
| MCL1 | myeloid cell leukemia 1 | -0.025792 |
| ANO6 | anoctamin 6 | -0.0257222 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0255851 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0255658 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0253208 |
| TRIM56 | tripartite motif containing 56 | -0.0250524 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0250126 |
| GOLGB1 | golgin B1 | -0.0250026 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | -0.0249024 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0245287 |
| HLA-A | major histocompatibility complex, class I, A | -0.0243186 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0242896 |
| IER3 | immediate early response 3 | -0.0241183 |
| EGR1 | early growth response 1 | -0.0240951 |
| B2M | beta-2-microglobulin | -0.024089 |
