| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0406601 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0391527 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0290289 |
| RAD51B | RAD51 paralog B | 0.0208548 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0202539 |
| MACC1 | metastasis associated in colon cancer 1 | 0.01986 |
| EXOC4 | exocyst complex component 4 | 0.0195399 |
| PARD3B | par-3 family cell polarity regulator beta | 0.019518 |
| FAT1 | FAT atypical cadherin 1 | 0.0191645 |
| POTEF | POTE ankyrin domain family, member F | 0.018728 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0174023 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0172433 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0171687 |
| WWOX | WW domain containing oxidoreductase | 0.0169264 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0161368 |
| RPL21 | ribosomal protein L21 | 0.0157404 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0156465 |
| PCBP2 | poly(rC) binding protein 2 | 0.0151373 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0150914 |
| ECT2 | epithelial cell transforming 2 | 0.0145378 |
| FHIT | fragile histidine triad | 0.0141958 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.01419 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0140995 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0136654 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0135294 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0135216 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.013453 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 | 0.0134207 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0132904 |
| RPL3 | ribosomal protein L3 | 0.0130409 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0128621 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0127542 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0122758 |
| YAP1 | Yes-associated protein 1 | 0.0122147 |
| HDAC9 | histone deacetylase 9 | 0.0118192 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0117831 |
| SSRP1 | structure specific recognition protein 1 | 0.0117619 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0114416 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0110724 |
| RBM12 | RNA binding motif protein 12 | 0.0109834 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0108702 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0107239 |
| TMEM65 | transmembrane protein 65 | 0.0104593 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.0104138 |
| CRY1 | cryptochrome circadian clock 1 | 0.00995047 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.00991426 |
| TRIM2 | tripartite motif containing 2 | 0.00982252 |
| NRXN1 | neurexin 1 | 0.00981271 |
| TBC1D5 | TBC1 domain family, member 5 | 0.00979844 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain | 0.0097531 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.00968129 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.00965563 |
| SMYD3 | SET and MYND domain containing 3 | 0.00965194 |
| OLA1 | Obg-like ATPase 1 | 0.00959463 |
| ATG5 | autophagy related 5 | 0.00957343 |
| ZNF407 | zinc finger protein 407 | 0.00955225 |
| NAV3 | neuron navigator 3 | 0.00954859 |
| KIF26B | kinesin family member 26B | 0.00941336 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00929025 |
| TPM3 | tropomyosin 3 | 0.00926702 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0092074 |
| DACH1 | dachshund family transcription factor 1 | 0.0091344 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein | 0.00906343 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.00903643 |
| PCDH1 | protocadherin 1 | 0.00903017 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00888158 |
| PROX1 | prospero homeobox 1 | 0.00883304 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.00879477 |
| MED13L | mediator complex subunit 13-like | 0.00866429 |
| ZNF277 | zinc finger protein 277 | 0.00864889 |
| MNT | MAX network transcriptional repressor | 0.00854915 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.00848288 |
| PTEN | phosphatase and tensin homolog | 0.0084047 |
| ZNF462 | zinc finger protein 462 | 0.00837954 |
| ITGA6 | integrin, alpha 6 | 0.00836161 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.00835689 |
| L1CAM | L1 cell adhesion molecule | 0.00835209 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.00828396 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 0.00820927 |
| GSK3B | glycogen synthase kinase 3 beta | 0.00813156 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00805895 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.00795664 |
| MYO5B | myosin VB | 0.00794723 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.00794492 |
| SYTL2 | synaptotagmin-like 2 | 0.00793907 |
| NUP205 | nucleoporin 205kDa | 0.00793479 |
| CFAP161 | cilia and flagella associated protein 161 | 0.0077879 |
| DENND1B | DENN/MADD domain containing 1B | 0.00773299 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00773123 |
| CD24 | CD24 molecule | 0.00772169 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.00770838 |
| ZNF704 | zinc finger protein 704 | 0.00769149 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.00764282 |
| LDHB | lactate dehydrogenase B | 0.00762483 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.00760808 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.00760117 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.00756161 |
| FAR1 | fatty acyl CoA reductase 1 | 0.00755255 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.00753133 |
| NPAS3 | neuronal PAS domain protein 3 | 0.00746814 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.299618 |
| FTL | ferritin, light polypeptide | -0.190661 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.129685 |
| TMSB10 | thymosin beta 10 | -0.0924522 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0867418 |
| KRT18 | keratin 18, type I | -0.0835197 |
| GNAS | GNAS complex locus | -0.0764788 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0748763 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0713626 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0713054 |
| GOLGA4 | golgin A4 | -0.068323 |
| CANX | calnexin | -0.0665454 |
| RPL35A | ribosomal protein L35a | -0.0648137 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0621883 |
| IER3 | immediate early response 3 | -0.0607774 |
| H1-0 | H1.0 linker histone | -0.0596852 |
| RPLP1 | ribosomal protein, large, P1 | -0.0582526 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.056824 |
| EPCAM | epithelial cell adhesion molecule | -0.0536637 |
| RPS21 | ribosomal protein S21 | -0.0534787 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0530254 |
| AHNAK | AHNAK nucleoprotein | -0.0529926 |
| RBM39 | RNA binding motif protein 39 | -0.0524954 |
| IFRD1 | interferon-related developmental regulator 1 | -0.052181 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0516011 |
| TOP1 | topoisomerase (DNA) I | -0.0510294 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0500246 |
| EZR | ezrin | -0.0486785 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0482492 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0480525 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.046987 |
| TMEM123 | transmembrane protein 123 | -0.0468834 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0467141 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0462619 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0462552 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0460612 |
| JMJD1C | jumonji domain containing 1C | -0.0453454 |
| RPS6 | ribosomal protein S6 | -0.0445934 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0440149 |
| HDLBP | high density lipoprotein binding protein | -0.0438413 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.042901 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0415569 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0415276 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.040475 |
| RPS27A | ribosomal protein S27a | -0.0397268 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0386393 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0386186 |
| SQSTM1 | sequestosome 1 | -0.0384577 |
| RPL31 | ribosomal protein L31 | -0.0384156 |
| HM13 | histocompatibility (minor) 13 | -0.0382524 |
| B2M | beta-2-microglobulin | -0.0380207 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0379279 |
| S100A6 | S100 calcium binding protein A6 | -0.0378577 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0376154 |
| TMSB4X | thymosin beta 4, X-linked | -0.0374942 |
| RPL32 | ribosomal protein L32 | -0.0374584 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0373549 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0370598 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0367636 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0366534 |
| RPS24 | ribosomal protein S24 | -0.0366412 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0361807 |
| RPL8 | ribosomal protein L8 | -0.0361684 |
| RPS3 | ribosomal protein S3 | -0.0354713 |
| RPL12 | ribosomal protein L12 | -0.0352215 |
| RPLP2 | ribosomal protein, large, P2 | -0.0350644 |
| RBM27 | RNA binding motif protein 27 | -0.0347122 |
| RPS13 | ribosomal protein S13 | -0.0343011 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0342759 |
| ARF1 | ADP-ribosylation factor 1 | -0.0342755 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0342436 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.034239 |
| RBM25 | RNA binding motif protein 25 | -0.0340413 |
| CD2AP | CD2-associated protein | -0.0339558 |
| ACTG1 | actin gamma 1 | -0.0338598 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0337637 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0330345 |
| RPL18 | ribosomal protein L18 | -0.0329951 |
| RPS19 | ribosomal protein S19 | -0.0327278 |
| SDC4 | syndecan 4 | -0.0325572 |
| RTN3 | reticulon 3 | -0.0324492 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0321264 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.032052 |
| RPL34 | ribosomal protein L34 | -0.0319 |
| ZNF217 | zinc finger protein 217 | -0.0315417 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0313638 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0313435 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0312084 |
| RPS14 | ribosomal protein S14 | -0.0311142 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0310767 |
| S100A10 | S100 calcium binding protein A10 | -0.0306128 |
| RPL7A | ribosomal protein L7a | -0.0305298 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0303987 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0303015 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0302213 |
| TPM4 | tropomyosin 4 | -0.0300181 |
| RPL28 | ribosomal protein L28 | -0.0299365 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0295502 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0295287 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0295048 |
