| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT8 | keratin 8, type II | 0.0904163 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0657146 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0617042 |
| CDH13 | cadherin 13 | 0.057893 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0471565 |
| KRT18 | keratin 18, type I | 0.0412394 |
| ITGA6 | integrin, alpha 6 | 0.0377072 |
| TMSB10 | thymosin beta 10 | 0.0372195 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0351236 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.033572 |
| FLNB | filamin B, beta | 0.0315214 |
| CCND1 | cyclin D1 | 0.0308698 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0307354 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.029304 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0291639 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0276183 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0254463 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0249367 |
| PCBP2 | poly(rC) binding protein 2 | 0.0247633 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0243293 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0242104 |
| ETNK1 | ethanolamine kinase 1 | 0.0240288 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0230506 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0220016 |
| TPM4 | tropomyosin 4 | 0.0218973 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0216093 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0208151 |
| HMGA1 | high mobility group AT-hook 1 | 0.0199246 |
| RPL35A | ribosomal protein L35a | 0.0193389 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0188231 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0175608 |
| NAV2 | neuron navigator 2 | 0.01732 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0167853 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0167678 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0166177 |
| INSIG2 | insulin induced gene 2 | 0.0162218 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0157294 |
| ENO1 | enolase 1, (alpha) | 0.0156583 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0156437 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0154149 |
| RPL23 | ribosomal protein L23 | 0.0153795 |
| ITGB4 | integrin, beta 4 | 0.014404 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.0143987 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0143404 |
| OLA1 | Obg-like ATPase 1 | 0.0143335 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0143246 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0140774 |
| S100A6 | S100 calcium binding protein A6 | 0.0136215 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0132526 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0131604 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0129772 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0129605 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0129278 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.012872 |
| PLIN2 | perilipin 2 | 0.012844 |
| MED13L | mediator complex subunit 13-like | 0.0125682 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0125392 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0124541 |
| KRT5 | keratin 5, type II | 0.0122201 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0122172 |
| RASA3 | RAS p21 protein activator 3 | 0.0117295 |
| NUP58 | nucleoporin 58 | 0.0116899 |
| EPB41L4A | erythrocyte membrane protein band 4.1 like 4A | 0.0116753 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0115649 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0112277 |
| AFDN | afadin, adherens junction formation factor | 0.0112043 |
| VIM | vimentin | 0.0111984 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0109366 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0108729 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0107681 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0107029 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0106338 |
| TMSB4X | thymosin beta 4, X-linked | 0.0106045 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0105066 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0104831 |
| TMEM41B | transmembrane protein 41B | 0.0104669 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0103535 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0102881 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0102547 |
| SPNS2 | spinster homolog 2 (Drosophila) | 0.0102044 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0100576 |
| MEMO1 | mediator of cell motility 1 | 0.00999024 |
| ECT2 | epithelial cell transforming 2 | 0.00992281 |
| COPA | coatomer protein complex, subunit alpha | 0.00981664 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00969157 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.00960272 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00943432 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.00940416 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.00927317 |
| ANXA2 | annexin A2 | 0.00916291 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.00914508 |
| PDE10A | phosphodiesterase 10A | 0.00892608 |
| WDR45B | WD repeat domain 45B | 0.0088987 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | 0.00886532 |
| LSAMP | limbic system-associated membrane protein | 0.0087552 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00873573 |
| FN1 | fibronectin 1 | 0.00872349 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.00864148 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.00863685 |
| TRAF3 | TNF receptor-associated factor 3 | 0.00861175 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.185899 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.132848 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.124789 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0965627 |
| SYT1 | synaptotagmin I | -0.0954284 |
| LMO7 | LIM domain 7 | -0.0894795 |
| RPS2 | ribosomal protein S2 | -0.0862197 |
| DSPP | dentin sialophosphoprotein | -0.0833112 |
| TNS3 | tensin 3 | -0.0820668 |
| RPS6 | ribosomal protein S6 | -0.0818079 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0730989 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0704728 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0589579 |
| ATXN1 | ataxin 1 | -0.0583672 |
| MKI67 | marker of proliferation Ki-67 | -0.056471 |
| RPL26 | ribosomal protein L26 | -0.0551773 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0548253 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0541108 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0534688 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0530846 |
| PROX1 | prospero homeobox 1 | -0.0524864 |
| YAP1 | Yes-associated protein 1 | -0.0518944 |
| RBM39 | RNA binding motif protein 39 | -0.0511398 |
| BPTF | bromodomain PHD finger transcription factor | -0.0508994 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0505058 |
| DST | dystonin | -0.0491998 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0489562 |
| AOPEP | aminopeptidase O (putative) | -0.0486589 |
| BCL2L1 | BCL2-like 1 | -0.0484565 |
| RPS3 | ribosomal protein S3 | -0.0484165 |
| KIZ | kizuna centrosomal protein | -0.0473455 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0470502 |
| EZR | ezrin | -0.0470278 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0468746 |
| VGLL4 | vestigial-like family member 4 | -0.0458173 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0442059 |
| CENPF | centromere protein F, 350/400kDa | -0.0441676 |
| RPS12 | ribosomal protein S12 | -0.0436676 |
| EFNB2 | ephrin-B2 | -0.0436359 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0432805 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0432394 |
| OXR1 | oxidation resistance 1 | -0.0429661 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0427393 |
| RPL7 | ribosomal protein L7 | -0.042565 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0423612 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0421506 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0413004 |
| RPL38 | ribosomal protein L38 | -0.0412134 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | -0.0404655 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0403705 |
| HDAC4 | histone deacetylase 4 | -0.0395176 |
| RPS8 | ribosomal protein S8 | -0.0395148 |
| AXIN2 | axin 2 | -0.0383613 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0380597 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0370795 |
| RUNX1 | runt-related transcription factor 1 | -0.0351206 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0351185 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0350983 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0348732 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0348664 |
| RPS13 | ribosomal protein S13 | -0.0346719 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.034609 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0343876 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0338372 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0336453 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.032962 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0326707 |
| SEPTIN9 | septin 9 | -0.0326007 |
| RPL19 | ribosomal protein L19 | -0.0324363 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0323849 |
| STK4 | serine/threonine kinase 4 | -0.0323268 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | -0.0322132 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0318477 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0318372 |
| SESN3 | sestrin 3 | -0.0316993 |
| WWOX | WW domain containing oxidoreductase | -0.0316734 |
| RPL3 | ribosomal protein L3 | -0.0315951 |
| PCM1 | pericentriolar material 1 | -0.0315811 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0315053 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0311843 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0311158 |
| H1-4 | H1.4 linker histone, cluster member | -0.0311031 |
| SPATA13 | spermatogenesis associated 13 | -0.0311001 |
| UTRN | utrophin | -0.0310027 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0308749 |
| RNF43 | ring finger protein 43 | -0.0307579 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0307493 |
| GOLGB1 | golgin B1 | -0.0304484 |
| TXNIP | thioredoxin interacting protein | -0.0303737 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0302928 |
| SMAD3 | SMAD family member 3 | -0.03025 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0302447 |
| RPL36A | ribosomal protein L36a | -0.0301179 |
| ANO6 | anoctamin 6 | -0.0295026 |
| HDAC8 | histone deacetylase 8 | -0.0294749 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0294614 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0294135 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0293875 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.0291562 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0289103 |
