| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bentamapimod perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bentamapimod_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0997534 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0977741 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0656466 |
| POTEF | POTE ankyrin domain family, member F | 0.0612213 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0525269 |
| CENPF | centromere protein F, 350/400kDa | 0.0507399 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.048355 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0479158 |
| HDAC9 | histone deacetylase 9 | 0.0468295 |
| SQSTM1 | sequestosome 1 | 0.0429475 |
| RPL23 | ribosomal protein L23 | 0.0428578 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0411087 |
| RPL12 | ribosomal protein L12 | 0.0398669 |
| LDHA | lactate dehydrogenase A | 0.0370345 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0340925 |
| RPL37A | ribosomal protein L37a | 0.0328804 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0321992 |
| RACK1 | receptor for activated C kinase 1 | 0.0321875 |
| RPS3 | ribosomal protein S3 | 0.0321828 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0318537 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0308504 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0298176 |
| RPLP2 | ribosomal protein, large, P2 | 0.0293105 |
| FOSL1 | FOS-like antigen 1 | 0.0279977 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0276659 |
| RPS19 | ribosomal protein S19 | 0.0275947 |
| RPLP1 | ribosomal protein, large, P1 | 0.0275156 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0270295 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0261066 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.02605 |
| EZR | ezrin | 0.0258839 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0257688 |
| SON | SON DNA binding protein | 0.0257077 |
| RPL26 | ribosomal protein L26 | 0.0256821 |
| RPS6 | ribosomal protein S6 | 0.0251448 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0244832 |
| RPS8 | ribosomal protein S8 | 0.0243081 |
| DSPP | dentin sialophosphoprotein | 0.0236291 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0236107 |
| ERBIN | erbb2 interacting protein | 0.023524 |
| KLF10 | Kruppel-like factor 10 | 0.0235008 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0233448 |
| TMSB4X | thymosin beta 4, X-linked | 0.0230443 |
| RPL19 | ribosomal protein L19 | 0.0229291 |
| TLE4 | transducin-like enhancer of split 4 | 0.0228764 |
| RPL28 | ribosomal protein L28 | 0.0225008 |
| ENO1 | enolase 1, (alpha) | 0.0224162 |
| RPS17 | ribosomal protein S17 | 0.0222885 |
| KLF6 | Kruppel-like factor 6 | 0.0222786 |
| RPL36 | ribosomal protein L36 | 0.0217755 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0213933 |
| RPS12 | ribosomal protein S12 | 0.0213425 |
| RPL35 | ribosomal protein L35 | 0.0211729 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0206045 |
| RND3 | Rho family GTPase 3 | 0.0205176 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0203297 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0202615 |
| B2M | beta-2-microglobulin | 0.0197279 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0192806 |
| SEPTIN7 | septin 7 | 0.0188335 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0183915 |
| MSN | moesin | 0.0183803 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0182768 |
| RPL31 | ribosomal protein L31 | 0.0182452 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0181189 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.018031 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0179239 |
| SERTAD2 | SERTA domain containing 2 | 0.0177504 |
| S100A11 | S100 calcium binding protein A11 | 0.0174698 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0174306 |
| FLNA | filamin A, alpha | 0.0173804 |
| RPS27 | ribosomal protein S27 | 0.0173617 |
| RPL32 | ribosomal protein L32 | 0.0169127 |
| IPO7 | importin 7 | 0.0167764 |
| SEC61G | Sec61 gamma subunit | 0.0166434 |
| RPS16 | ribosomal protein S16 | 0.0165642 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0165311 |
| YBX1 | Y box binding protein 1 | 0.0164259 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0164214 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0163887 |
| RPS14 | ribosomal protein S14 | 0.015966 |
| RPS23 | ribosomal protein S23 | 0.0158659 |
| RPL27 | ribosomal protein L27 | 0.0156276 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0152517 |
| RPL9 | ribosomal protein L9 | 0.0149905 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0149772 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.0147916 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0147801 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0147384 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0146592 |
| NUAK2 | NUAK family, SNF1-like kinase, 2 | 0.0146055 |
| FTL | ferritin, light polypeptide | 0.014588 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.01445 |
| RPS27A | ribosomal protein S27a | 0.0143777 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0143183 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0143004 |
| ACTN1 | actinin, alpha 1 | 0.0141098 |
| SMAD3 | SMAD family member 3 | 0.0140559 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0140444 |
| RPL11 | ribosomal protein L11 | 0.0139708 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.251858 |
| PLAT | plasminogen activator, tissue | -0.184441 |
| VIM | vimentin | -0.136219 |
| LOX | lysyl oxidase | -0.125449 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.121805 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.110669 |
| FBN1 | fibrillin 1 | -0.106384 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.104558 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.10224 |
| COL1A2 | collagen, type I, alpha 2 | -0.0965605 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0913196 |
| LOXL2 | lysyl oxidase-like 2 | -0.0870496 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0731938 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0618445 |
| COL5A2 | collagen, type V, alpha 2 | -0.0598921 |
| PODXL | podocalyxin-like | -0.0584609 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.058096 |
| NAV1 | neuron navigator 1 | -0.0564303 |
| COL5A1 | collagen, type V, alpha 1 | -0.0546077 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0532618 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0516968 |
| PRSS23 | protease, serine, 23 | -0.0514069 |
| AUTS2 | autism susceptibility candidate 2 | -0.0511768 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0505687 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0505178 |
| HLA-B | major histocompatibility complex, class I, B | -0.0500889 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0491722 |
| FRMD4A | FERM domain containing 4A | -0.0477829 |
| FN1 | fibronectin 1 | -0.0472998 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0469886 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0461017 |
| SUCNR1 | succinate receptor 1 | -0.0448328 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0444986 |
| GLIS3 | GLIS family zinc finger 3 | -0.0444146 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0439625 |
| CD99 | CD99 molecule | -0.0434856 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0428029 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0421192 |
| UBC | ubiquitin C | -0.0419714 |
| MAP4 | microtubule-associated protein 4 | -0.0409743 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0392867 |
| DST | dystonin | -0.0392486 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0383343 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0360407 |
| JAZF1 | JAZF zinc finger 1 | -0.035414 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0353397 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0351268 |
| STC1 | stanniocalcin 1 | -0.0347583 |
| CANX | calnexin | -0.0331406 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0330119 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0327365 |
| MYADM | myeloid-associated differentiation marker | -0.0327352 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0320665 |
| MX2 | MX dynamin-like GTPase 2 | -0.0319791 |
| OGA | O-GlcNAcase | -0.0318981 |
| TMSB10 | thymosin beta 10 | -0.0317764 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0310759 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0307527 |
| GPC6 | glypican 6 | -0.0306594 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0302277 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0301584 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0300744 |
| CUX1 | cut-like homeobox 1 | -0.0290886 |
| SPAG9 | sperm associated antigen 9 | -0.0290156 |
| HIP1 | huntingtin interacting protein 1 | -0.0286768 |
| ASPH | aspartate beta-hydroxylase | -0.0283096 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0271456 |
| RTN4 | reticulon 4 | -0.0270596 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0267007 |
| CEP170 | centrosomal protein 170kDa | -0.0265229 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0263022 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.026277 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0262652 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0260491 |
| FNDC3B | fibronectin type III domain containing 3B | -0.02582 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0257432 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0255886 |
| PGK1 | phosphoglycerate kinase 1 | -0.0253909 |
| SRPK2 | SRSF protein kinase 2 | -0.0253163 |
| CTSB | cathepsin B | -0.0252453 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0251269 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0249575 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0240356 |
| KIFAP3 | kinesin-associated protein 3 | -0.0238704 |
| MT2A | metallothionein 2A | -0.0237487 |
| MEIS2 | Meis homeobox 2 | -0.0236551 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0235173 |
| PXDN | peroxidasin | -0.0231045 |
| MT1X | metallothionein 1X | -0.0229636 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0229445 |
| SP3 | Sp3 transcription factor | -0.0229006 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0227131 |
| PARD3 | par-3 family cell polarity regulator | -0.0225943 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0224287 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0222462 |
| MMP12 | matrix metallopeptidase 12 | -0.0221595 |
| CDH13 | cadherin 13 | -0.021961 |
| AHNAK | AHNAK nucleoprotein | -0.02168 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0212187 |
| NRP1 | neuropilin 1 | -0.0210432 |
