| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bentamapimod perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bentamapimod_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.289582 |
| AREG | amphiregulin | 0.18385 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.120032 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0892954 |
| TMEM41B | transmembrane protein 41B | 0.0726361 |
| FTL | ferritin, light polypeptide | 0.0723138 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.067757 |
| RTN4 | reticulon 4 | 0.0665223 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.061792 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0588929 |
| RPS12 | ribosomal protein S12 | 0.0513303 |
| RPL37A | ribosomal protein L37a | 0.050194 |
| RPS8 | ribosomal protein S8 | 0.0493425 |
| PCBP2 | poly(rC) binding protein 2 | 0.0485017 |
| MATR3 | matrin 3 | 0.0478161 |
| RPL23 | ribosomal protein L23 | 0.0476102 |
| RPS3 | ribosomal protein S3 | 0.0464074 |
| JMJD1C | jumonji domain containing 1C | 0.0437904 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0433787 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.042884 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0420091 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0413026 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0395925 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0390131 |
| HLA-A | major histocompatibility complex, class I, A | 0.0387972 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0384214 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.0379449 |
| EZR | ezrin | 0.0373987 |
| POTEF | POTE ankyrin domain family, member F | 0.036982 |
| RACK1 | receptor for activated C kinase 1 | 0.0368462 |
| ZNF638 | zinc finger protein 638 | 0.036619 |
| RPS6 | ribosomal protein S6 | 0.0361818 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0355371 |
| PCM1 | pericentriolar material 1 | 0.0350137 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0346772 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0346234 |
| IPO7 | importin 7 | 0.0345799 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.034425 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0341192 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0334006 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0329227 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0328279 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0326121 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0323108 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0318747 |
| FNIP1 | folliculin interacting protein 1 | 0.0316909 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0314084 |
| SEPTIN7 | septin 7 | 0.0308199 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0303684 |
| EDN1 | endothelin 1 | 0.0303407 |
| TUBA1B | tubulin, alpha 1b | 0.0296318 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0293145 |
| PNN | pinin, desmosome associated protein | 0.0291444 |
| YBX1 | Y box binding protein 1 | 0.0288224 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.028775 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0282714 |
| ITSN2 | intersectin 2 | 0.0279749 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.027848 |
| SQSTM1 | sequestosome 1 | 0.0277621 |
| ZNF292 | zinc finger protein 292 | 0.0275206 |
| SBF2 | SET binding factor 2 | 0.0274661 |
| SETD5 | SET domain containing 5 | 0.0273237 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.027079 |
| TXNRD1 | thioredoxin reductase 1 | 0.0270303 |
| KLHL24 | kelch-like family member 24 | 0.0269635 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0267853 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.026345 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0258197 |
| LDHA | lactate dehydrogenase A | 0.0257442 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0256263 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.025556 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0254564 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0253837 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0251486 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0250215 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0249453 |
| LDHB | lactate dehydrogenase B | 0.0248455 |
| TNPO1 | transportin 1 | 0.0247952 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.024756 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0247558 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0246152 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.024292 |
| NF1 | neurofibromin 1 | 0.0242031 |
| YTHDC1 | YTH domain containing 1 | 0.0239934 |
| TPI1 | triosephosphate isomerase 1 | 0.0236655 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0234506 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0234382 |
| RPL5 | ribosomal protein L5 | 0.0234102 |
| VMP1 | vacuole membrane protein 1 | 0.0232829 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0232713 |
| DNAJC21 | DnaJ (Hsp40) homolog, subfamily C, member 21 | 0.0232438 |
| CCN2 | cellular communication network factor 2 | 0.0229027 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0228735 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0228332 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0226948 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0226854 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0221112 |
| NKTR | natural killer cell triggering receptor | 0.0220683 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | 0.0220681 |
| RPL11 | ribosomal protein L11 | 0.0220035 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | -0.354655 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.130459 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.11226 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0990281 |
| HMGA2 | high mobility group AT-hook 2 | -0.0966309 |
| TENM3 | teneurin transmembrane protein 3 | -0.0950568 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0807402 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0773296 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0733305 |
| AHNAK | AHNAK nucleoprotein | -0.0724449 |
| ACTG1 | actin gamma 1 | -0.0699432 |
| MMP12 | matrix metallopeptidase 12 | -0.0683716 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0676339 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0663131 |
| EHBP1 | EH domain binding protein 1 | -0.0634918 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0603051 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0591236 |
| DST | dystonin | -0.0561364 |
| PCDH7 | protocadherin 7 | -0.050584 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0488528 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0467725 |
| ZNF804A | zinc finger protein 804A | -0.046071 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0437841 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0431273 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0428594 |
| ADIPOR2 | adiponectin receptor 2 | -0.0423806 |
| NEBL | nebulette | -0.0414421 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0413408 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0405201 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0395546 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0395069 |
| HDAC9 | histone deacetylase 9 | -0.0379376 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.037639 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0375847 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0369312 |
| NHSL1 | NHS-like 1 | -0.0364963 |
| MTAP | methylthioadenosine phosphorylase | -0.0350115 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0341657 |
| AXIN2 | axin 2 | -0.034113 |
| YAP1 | Yes-associated protein 1 | -0.0340026 |
| FUS | FUS RNA binding protein | -0.0336961 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0331087 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0328395 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0324181 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.032077 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0313765 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0310785 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0310181 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0307621 |
| ZNF217 | zinc finger protein 217 | -0.0303494 |
| NUP98 | nucleoporin 98kDa | -0.0302391 |
| EPHA6 | EPH receptor A6 | -0.0302008 |
| H1-0 | H1.0 linker histone | -0.0298248 |
| NABP1 | nucleic acid binding protein 1 | -0.0297112 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0295503 |
| EDARADD | EDAR-associated death domain | -0.0294604 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0290206 |
| TMSB10 | thymosin beta 10 | -0.0290024 |
| COMMD10 | COMM domain containing 10 | -0.0286775 |
| RNF213 | ring finger protein 213 | -0.0285812 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0284365 |
| CMIP | c-Maf inducing protein | -0.0282676 |
| TMEM123 | transmembrane protein 123 | -0.0281467 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0279913 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0276621 |
| INTS6 | integrator complex subunit 6 | -0.0273058 |
| COL5A2 | collagen, type V, alpha 2 | -0.0269864 |
| MAP4 | microtubule-associated protein 4 | -0.0268724 |
| LMO7 | LIM domain 7 | -0.0268378 |
| SMYD3 | SET and MYND domain containing 3 | -0.0268132 |
| CANX | calnexin | -0.0263942 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0251926 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0250367 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0248071 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0247731 |
| RANBP17 | RAN binding protein 17 | -0.0243791 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0242883 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0240841 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.024023 |
| MAP1B | microtubule-associated protein 1B | -0.023898 |
| RPS9 | ribosomal protein S9 | -0.02321 |
| DIAPH3 | diaphanous-related formin 3 | -0.0231397 |
| ACLY | ATP citrate lyase | -0.0228242 |
| TMEM108 | transmembrane protein 108 | -0.0227572 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0225236 |
| TUBB | tubulin, beta class I | -0.0224686 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | -0.0223063 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0222684 |
| CCDC57 | coiled-coil domain containing 57 | -0.0222133 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0221996 |
| NFIB | nuclear factor I/B | -0.0221032 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.021837 |
| AEBP2 | AE binding protein 2 | -0.0217897 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0217774 |
| ACTN4 | actinin, alpha 4 | -0.021584 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0215508 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.021435 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0213912 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.021163 |
| WDR1 | WD repeat domain 1 | -0.0211311 |
