| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bentamapimod perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bentamapimod_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.143366 |
| SMAD3 | SMAD family member 3 | 0.116941 |
| EXT1 | exostosin glycosyltransferase 1 | 0.110424 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.10334 |
| LCN2 | lipocalin 2 | 0.0968831 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0956072 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0900583 |
| LMO7 | LIM domain 7 | 0.0858655 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0726547 |
| TJP1 | tight junction protein 1 | 0.0693342 |
| MYO1E | myosin IE | 0.0691421 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.065441 |
| NCKAP5 | NCK-associated protein 5 | 0.0585731 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0553553 |
| DST | dystonin | 0.0532944 |
| MCU | mitochondrial calcium uniporter | 0.0466933 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0466061 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0413557 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0406122 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0392791 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0376688 |
| LIMA1 | LIM domain and actin binding 1 | 0.0372759 |
| RPL23 | ribosomal protein L23 | 0.0370052 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0368834 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0363382 |
| ASPH | aspartate beta-hydroxylase | 0.0356702 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0353557 |
| MYO5B | myosin VB | 0.0351667 |
| ATXN1 | ataxin 1 | 0.0339603 |
| PDZD8 | PDZ domain containing 8 | 0.0333233 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0331981 |
| RBM47 | RNA binding motif protein 47 | 0.0324942 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0322456 |
| SIK3 | SIK family kinase 3 | 0.0317839 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0315859 |
| HKDC1 | hexokinase domain containing 1 | 0.0314445 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0306173 |
| NEBL | nebulette | 0.0304947 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0303937 |
| PERP | PERP, TP53 apoptosis effector | 0.0298058 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0296367 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0295354 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0295064 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0293859 |
| TRIM2 | tripartite motif containing 2 | 0.0289395 |
| ETV6 | ets variant 6 | 0.0289209 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0286088 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0285142 |
| TRERF1 | transcriptional regulating factor 1 | 0.0284198 |
| WWOX | WW domain containing oxidoreductase | 0.0279371 |
| YAP1 | Yes-associated protein 1 | 0.0278927 |
| EXPH5 | exophilin 5 | 0.0275798 |
| SFTPA2 | surfactant protein A2 | 0.0274659 |
| CDHR2 | cadherin-related family member 2 | 0.0274183 |
| SNX29 | sorting nexin 29 | 0.0272717 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0267466 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0266632 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0264574 |
| FHL2 | four and a half LIM domains 2 | 0.0258707 |
| SMYD3 | SET and MYND domain containing 3 | 0.0258468 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0257448 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0254306 |
| ITGB8 | integrin, beta 8 | 0.0253688 |
| VWA8 | von Willebrand factor A domain containing 8 | 0.0253329 |
| KLF6 | Kruppel-like factor 6 | 0.0251977 |
| SLK | STE20-like kinase | 0.0250964 |
| TMEM65 | transmembrane protein 65 | 0.0250706 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0249334 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0247629 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.024563 |
| TMC5 | transmembrane channel-like 5 | 0.024529 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0245243 |
| OCLN | occludin | 0.0242593 |
| CLOCK | clock circadian regulator | 0.0241208 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0240854 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0239132 |
| DUSP10 | dual specificity phosphatase 10 | 0.0238376 |
| RND3 | Rho family GTPase 3 | 0.0237712 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0234123 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0231776 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0230959 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.023053 |
| FTL | ferritin, light polypeptide | 0.0228969 |
| EREG | epiregulin | 0.021835 |
| TOX3 | TOX high mobility group box family member 3 | 0.0217052 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0215207 |
| RPL7L1 | ribosomal protein L7-like 1 | 0.021483 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0214828 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0212069 |
| USP54 | ubiquitin specific peptidase 54 | 0.0210359 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0209932 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0207034 |
| DUSP16 | dual specificity phosphatase 16 | 0.0204918 |
| UBAP1 | ubiquitin associated protein 1 | 0.0204591 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0203867 |
| RPS12 | ribosomal protein S12 | 0.0202545 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.020041 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.020008 |
| EPCAM | epithelial cell adhesion molecule | 0.0199593 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0199156 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.152997 |
| LYZ | lysozyme | -0.127606 |
| FNDC3B | fibronectin type III domain containing 3B | -0.120432 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.11817 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.118095 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.108975 |
| NDRG1 | N-myc downstream regulated 1 | -0.107363 |
| TXNIP | thioredoxin interacting protein | -0.100053 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0962729 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0886057 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0878348 |
| H1-0 | H1.0 linker histone | -0.0864646 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0833213 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0820301 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0778684 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0750729 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0743826 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.067543 |
| NPSR1 | neuropeptide S receptor 1 | -0.0668111 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0660313 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.063896 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0619049 |
| PGK1 | phosphoglycerate kinase 1 | -0.0614607 |
| PKM | pyruvate kinase, muscle | -0.0605558 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0600572 |
| PRKCA | protein kinase C, alpha | -0.0579768 |
| EGR1 | early growth response 1 | -0.0575736 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0571411 |
| LAMA4 | laminin, alpha 4 | -0.0545554 |
| PTMA | prothymosin, alpha | -0.0545027 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0543966 |
| SSH2 | slingshot protein phosphatase 2 | -0.0527963 |
| HLA-B | major histocompatibility complex, class I, B | -0.0523542 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.052016 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0519789 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0510317 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0506186 |
| UBC | ubiquitin C | -0.0497981 |
| CANX | calnexin | -0.0474444 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0473666 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0473186 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0470067 |
| GOLGB1 | golgin B1 | -0.0464436 |
| IRF1 | interferon regulatory factor 1 | -0.0460545 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0460525 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0460474 |
| ITGA6 | integrin, alpha 6 | -0.0459887 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0442795 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0441608 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.04416 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0438809 |
| ABHD2 | abhydrolase domain containing 2 | -0.0430178 |
| MXD1 | MAX dimerization protein 1 | -0.041949 |
| AHI1 | Abelson helper integration site 1 | -0.0407166 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0406308 |
| SQSTM1 | sequestosome 1 | -0.0404952 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0400995 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0399648 |
| PLSCR2 | phospholipid scramblase 2 | -0.0397885 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0394747 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0394099 |
| WDR45B | WD repeat domain 45B | -0.0391556 |
| RNF149 | ring finger protein 149 | -0.0385475 |
| ANXA2 | annexin A2 | -0.03813 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0374873 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0374481 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0373198 |
| CCNL1 | cyclin L1 | -0.0369159 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0363911 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0363209 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0360798 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0357965 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0349367 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.034311 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0341035 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.0339201 |
| HLA-E | major histocompatibility complex, class I, E | -0.0339064 |
| CDCP1 | CUB domain containing protein 1 | -0.0334192 |
| AREG | amphiregulin | -0.033389 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0333767 |
| TNS4 | tensin 4 | -0.0332073 |
| SDC4 | syndecan 4 | -0.0331087 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0330014 |
| RBM39 | RNA binding motif protein 39 | -0.0328544 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0326099 |
| B3GALT5 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 | -0.0325483 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0323205 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0322462 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0321425 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0317445 |
| MCL1 | myeloid cell leukemia 1 | -0.0313133 |
| KRT19 | keratin 19, type I | -0.0312147 |
| EZR | ezrin | -0.0312011 |
| PTGR1 | prostaglandin reductase 1 | -0.031096 |
| TMEM123 | transmembrane protein 123 | -0.0309183 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0308418 |
| TFRC | transferrin receptor | -0.0307936 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0303144 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0302578 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0301819 |
