| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bentamapimod perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bentamapimod_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.250698 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0644805 |
| RPS6 | ribosomal protein S6 | 0.0632332 |
| RPS12 | ribosomal protein S12 | 0.0594051 |
| FTL | ferritin, light polypeptide | 0.0587952 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0483477 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.047599 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0460647 |
| B2M | beta-2-microglobulin | 0.0438926 |
| RPS19 | ribosomal protein S19 | 0.0437625 |
| RPS8 | ribosomal protein S8 | 0.0423323 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0422537 |
| LDHA | lactate dehydrogenase A | 0.0410551 |
| RPL9 | ribosomal protein L9 | 0.0372188 |
| RPL37A | ribosomal protein L37a | 0.0368926 |
| RPL23 | ribosomal protein L23 | 0.0358406 |
| POTEF | POTE ankyrin domain family, member F | 0.0331281 |
| RPL12 | ribosomal protein L12 | 0.0311405 |
| RPL18 | ribosomal protein L18 | 0.0306657 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0305722 |
| PCBP2 | poly(rC) binding protein 2 | 0.0304051 |
| VEGFA | vascular endothelial growth factor A | 0.0303498 |
| RPS3 | ribosomal protein S3 | 0.0300964 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0267033 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.024153 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0237678 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0221153 |
| RPS27 | ribosomal protein S27 | 0.0221013 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0221009 |
| SON | SON DNA binding protein | 0.0220939 |
| RPL36 | ribosomal protein L36 | 0.0214825 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0214211 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.021067 |
| NEBL | nebulette | 0.020974 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0204994 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0200399 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0198613 |
| RPS17 | ribosomal protein S17 | 0.0195316 |
| TPI1 | triosephosphate isomerase 1 | 0.0193199 |
| RPS26 | ribosomal protein S26 | 0.0191362 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0188405 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0185998 |
| RACK1 | receptor for activated C kinase 1 | 0.0182311 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0179508 |
| RPLP0 | ribosomal protein, large, P0 | 0.0178077 |
| NUCB2 | nucleobindin 2 | 0.0176299 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0176043 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0167361 |
| RPS14 | ribosomal protein S14 | 0.0165234 |
| RPL21 | ribosomal protein L21 | 0.0165225 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0163046 |
| CCDC6 | coiled-coil domain containing 6 | 0.0161678 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0160258 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0157698 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.015467 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0151391 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.015121 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.015098 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0150478 |
| RPL31 | ribosomal protein L31 | 0.0150233 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | 0.0149808 |
| PDZD8 | PDZ domain containing 8 | 0.0147817 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0147719 |
| RPL7 | ribosomal protein L7 | 0.0147698 |
| PTEN | phosphatase and tensin homolog | 0.0147539 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0147502 |
| HLA-A | major histocompatibility complex, class I, A | 0.0145586 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0145358 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.0145068 |
| CCNC | cyclin C | 0.0143702 |
| MT2A | metallothionein 2A | 0.014369 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0141932 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0140973 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0140063 |
| UBXN4 | UBX domain protein 4 | 0.0139821 |
| RPLP2 | ribosomal protein, large, P2 | 0.0136244 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0130264 |
| SSRP1 | structure specific recognition protein 1 | 0.0128828 |
| KLF10 | Kruppel-like factor 10 | 0.012816 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0128016 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0127445 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0126982 |
| RBM17 | RNA binding motif protein 17 | 0.0125397 |
| PRDX1 | peroxiredoxin 1 | 0.0124163 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0123881 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0123803 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0123116 |
| TAGLN2 | transgelin 2 | 0.0122932 |
| RPL26 | ribosomal protein L26 | 0.0122311 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0122056 |
| DNAJC8 | DnaJ (Hsp40) homolog, subfamily C, member 8 | 0.0121445 |
| RPL10A | ribosomal protein L10a | 0.012132 |
| TMF1 | TATA element modulatory factor 1 | 0.0121287 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.01211 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0118279 |
| SET | SET nuclear proto-oncogene | 0.0118195 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.0117971 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0117406 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0117171 |
| RPL37 | ribosomal protein L37 | 0.0116644 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.266869 |
| NPSR1 | neuropeptide S receptor 1 | -0.201616 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.166283 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.16214 |
| PTMA | prothymosin, alpha | -0.15793 |
| ANXA2 | annexin A2 | -0.112209 |
| VCL | vinculin | -0.111037 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.106255 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.105904 |
| FLNB | filamin B, beta | -0.0998532 |
| AHNAK | AHNAK nucleoprotein | -0.099505 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0955698 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0940317 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.091958 |
| ITGA6 | integrin, alpha 6 | -0.0877581 |
| ANTXR2 | anthrax toxin receptor 2 | -0.08544 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0848697 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0771668 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0748498 |
| ONECUT3 | one cut homeobox 3 | -0.0740452 |
| PIGR | polymeric immunoglobulin receptor | -0.073905 |
| MYO1E | myosin IE | -0.0733624 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0732813 |
| ACTN4 | actinin, alpha 4 | -0.0686391 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.067854 |
| TMSB10 | thymosin beta 10 | -0.062198 |
| TPM4 | tropomyosin 4 | -0.0580869 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0579704 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0560791 |
| PARD3 | par-3 family cell polarity regulator | -0.0534997 |
| H1-0 | H1.0 linker histone | -0.0534103 |
| FAT1 | FAT atypical cadherin 1 | -0.0508045 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0480106 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0474107 |
| KRT8 | keratin 8, type II | -0.0473065 |
| GPHN | gephyrin | -0.0472368 |
| NDRG1 | N-myc downstream regulated 1 | -0.0471792 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0461066 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0458488 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0448109 |
| CANX | calnexin | -0.0430595 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0424663 |
| LAMA4 | laminin, alpha 4 | -0.0423679 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0423435 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0417519 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0414785 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0413919 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0413192 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0411051 |
| EZR | ezrin | -0.0406343 |
| IER3 | immediate early response 3 | -0.040548 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0402924 |
| NFIA | nuclear factor I/A | -0.0400238 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0394455 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0393653 |
| MSI2 | musashi RNA-binding protein 2 | -0.0393002 |
| RBM39 | RNA binding motif protein 39 | -0.038658 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0381349 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.03806 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.037893 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0378376 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.037523 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0358464 |
| USP53 | ubiquitin specific peptidase 53 | -0.0354918 |
| AGR2 | anterior gradient 2 | -0.0353224 |
| ACTG1 | actin gamma 1 | -0.0352265 |
| DENND1A | DENN/MADD domain containing 1A | -0.03501 |
| PRELID2 | PRELI domain containing 2 | -0.0349278 |
| MED13L | mediator complex subunit 13-like | -0.0346331 |
| FBXO11 | F-box protein 11 | -0.0343519 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0340409 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0337654 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0333384 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0332296 |
| RREB1 | ras responsive element binding protein 1 | -0.0330498 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.032518 |
| GDF15 | growth differentiation factor 15 | -0.0322751 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0322568 |
| FOXO1 | forkhead box O1 | -0.0320338 |
| FAM13A | family with sequence similarity 13, member A | -0.0320194 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0319106 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0318345 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0313939 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0311879 |
| TNS4 | tensin 4 | -0.0308211 |
| CUX1 | cut-like homeobox 1 | -0.030808 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0306601 |
| PGK1 | phosphoglycerate kinase 1 | -0.0305841 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.030457 |
| SBF2 | SET binding factor 2 | -0.0301726 |
| MAP4 | microtubule-associated protein 4 | -0.0300773 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0297297 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0296397 |
| HDLBP | high density lipoprotein binding protein | -0.0295421 |
| VMP1 | vacuole membrane protein 1 | -0.0293119 |
| PALLD | palladin, cytoskeletal associated protein | -0.0293055 |
| LMO7 | LIM domain 7 | -0.0292741 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0291725 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0288153 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0286877 |
