| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bentamapimod perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bentamapimod_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.06188 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0591013 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0489598 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0488339 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0454136 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0398602 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0394585 |
| HLA-A | major histocompatibility complex, class I, A | 0.0386688 |
| MYOF | myoferlin | 0.0377211 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0364471 |
| HLA-B | major histocompatibility complex, class I, B | 0.0362475 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0319866 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0318935 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0314213 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0301181 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.027958 |
| IL6 | interleukin 6 | 0.0265724 |
| GOLGA4 | golgin A4 | 0.0261029 |
| EGFR | epidermal growth factor receptor | 0.0252162 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0222076 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0218703 |
| COPA | coatomer protein complex, subunit alpha | 0.0213611 |
| KYNU | kynureninase | 0.0208616 |
| LDHA | lactate dehydrogenase A | 0.0206581 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0204325 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0201292 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.020061 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0199424 |
| B2M | beta-2-microglobulin | 0.0198255 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.019327 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0191539 |
| DYM | dymeclin | 0.0185178 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0181304 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0176098 |
| ANGPTL4 | angiopoietin-like 4 | 0.0174379 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0171524 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0170681 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0167603 |
| ANO6 | anoctamin 6 | 0.0167577 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0166195 |
| FAM107B | family with sequence similarity 107, member B | 0.016566 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0163702 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.016271 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0160363 |
| ASTN2 | astrotactin 2 | 0.0159526 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0159033 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0156764 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0156475 |
| MYO1E | myosin IE | 0.0154032 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.015144 |
| INO80 | INO80 complex subunit | 0.0148402 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0148117 |
| FOSL1 | FOS-like antigen 1 | 0.0146787 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0146272 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0144492 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.014441 |
| ERBIN | erbb2 interacting protein | 0.0142197 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0141904 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0141848 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.013952 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0139165 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0137358 |
| USP36 | ubiquitin specific peptidase 36 | 0.0136763 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0135881 |
| MYADM | myeloid-associated differentiation marker | 0.0135003 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0134317 |
| ARRDC3 | arrestin domain containing 3 | 0.013397 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0133826 |
| CDC73 | cell division cycle 73 | 0.0131325 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0131131 |
| FTO | fat mass and obesity associated | 0.0130597 |
| SRP54 | signal recognition particle 54kDa | 0.0130585 |
| SCFD1 | sec1 family domain containing 1 | 0.0130564 |
| ATF4 | activating transcription factor 4 | 0.0127393 |
| FOXO3 | forkhead box O3 | 0.0126297 |
| STC2 | stanniocalcin 2 | 0.0125601 |
| SEC24A | SEC24 family member A | 0.0125186 |
| VRK2 | vaccinia related kinase 2 | 0.0125164 |
| SBF2 | SET binding factor 2 | 0.0125059 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0122252 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0121218 |
| CTBP2 | C-terminal binding protein 2 | 0.0121148 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0120877 |
| KIF13A | kinesin family member 13A | 0.0119778 |
| GOLGB1 | golgin B1 | 0.0119493 |
| PSEN1 | presenilin 1 | 0.0119226 |
| WWC2 | WW and C2 domain containing 2 | 0.0119127 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0117891 |
| SVIL | supervillin | 0.0116646 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.011626 |
| SMAD4 | SMAD family member 4 | 0.0115603 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.011554 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0115074 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0115052 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.011404 |
| HM13 | histocompatibility (minor) 13 | 0.0113884 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0113642 |
| MED13 | mediator complex subunit 13 | 0.0113192 |
| PCNX4 | pecanex 4 | 0.0112644 |
| KIAA0319 | KIAA0319 | 0.0112338 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.205356 |
| TMSB10 | thymosin beta 10 | -0.14781 |
| MT2A | metallothionein 2A | -0.12704 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.119686 |
| TXNRD1 | thioredoxin reductase 1 | -0.107219 |
| GRAMD1B | GRAM domain containing 1B | -0.105353 |
| VIM | vimentin | -0.10228 |
| PTMA | prothymosin, alpha | -0.101672 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0917541 |
| FTL | ferritin, light polypeptide | -0.0834833 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0824048 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0815592 |
| ACTG1 | actin gamma 1 | -0.0809625 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.071336 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0693688 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0635522 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0631631 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0579616 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0559039 |
| MCL1 | myeloid cell leukemia 1 | -0.0543851 |
| IGF2 | insulin-like growth factor 2 | -0.0472225 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0464937 |
| PKM | pyruvate kinase, muscle | -0.0447211 |
| RPS21 | ribosomal protein S21 | -0.0445187 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0419279 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0411747 |
| EGR1 | early growth response 1 | -0.040796 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0400565 |
| RPS29 | ribosomal protein S29 | -0.0399956 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0395519 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0391562 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0390329 |
| RPLP1 | ribosomal protein, large, P1 | -0.0382447 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0379396 |
| TPM4 | tropomyosin 4 | -0.0366797 |
| USP3 | ubiquitin specific peptidase 3 | -0.0363356 |
| ASPH | aspartate beta-hydroxylase | -0.0359118 |
| RTN4 | reticulon 4 | -0.0356977 |
| ANXA2 | annexin A2 | -0.0350726 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0349781 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0336029 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0334183 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0333076 |
| RPS23 | ribosomal protein S23 | -0.032988 |
| RPL35A | ribosomal protein L35a | -0.0329579 |
| RPS27A | ribosomal protein S27a | -0.0328966 |
| RRM2 | ribonucleotide reductase M2 | -0.0322315 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0321681 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.031408 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0313166 |
| RPL8 | ribosomal protein L8 | -0.0308583 |
| BICC1 | BicC family RNA binding protein 1 | -0.0302396 |
| MKI67 | marker of proliferation Ki-67 | -0.0289934 |
| YBX1 | Y box binding protein 1 | -0.0286259 |
| RPL19 | ribosomal protein L19 | -0.0281129 |
| RBM39 | RNA binding motif protein 39 | -0.02794 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0272213 |
| AREG | amphiregulin | -0.0270342 |
| PFDN2 | prefoldin subunit 2 | -0.0267053 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.026697 |
| RPL7 | ribosomal protein L7 | -0.0264106 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0263242 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0262538 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0259828 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0257056 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0257032 |
| HMGB1 | high mobility group box 1 | -0.0256916 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0254454 |
| TMEM123 | transmembrane protein 123 | -0.0253958 |
| RPL11 | ribosomal protein L11 | -0.0253674 |
| NNMT | nicotinamide N-methyltransferase | -0.0253427 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0252108 |
| ZNF292 | zinc finger protein 292 | -0.0248364 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0246638 |
| RPL13A | ribosomal protein L13a | -0.0246077 |
| KLF6 | Kruppel-like factor 6 | -0.0244533 |
| CENPF | centromere protein F, 350/400kDa | -0.024343 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0241355 |
| RPS25 | ribosomal protein S25 | -0.0240422 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0236022 |
| HMGA1 | high mobility group AT-hook 1 | -0.0235848 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0233585 |
| CAVIN1 | caveolae associated protein 1 | -0.0226894 |
| PDE8A | phosphodiesterase 8A | -0.0223773 |
| RPS15 | ribosomal protein S15 | -0.0223578 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.022302 |
| CANX | calnexin | -0.0222293 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0222262 |
| ZNF207 | zinc finger protein 207 | -0.0220392 |
| EFNA5 | ephrin-A5 | -0.021862 |
| RPL4 | ribosomal protein L4 | -0.0217114 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0214288 |
| RPS16 | ribosomal protein S16 | -0.0214188 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0213444 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0212719 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0211821 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0211622 |
| FBXO11 | F-box protein 11 | -0.0210859 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0210833 |
| FUS | FUS RNA binding protein | -0.0209784 |
