| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bentamapimod perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bentamapimod_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.175153 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.138833 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.107504 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0722539 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0633821 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0614034 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0604067 |
| TPI1 | triosephosphate isomerase 1 | 0.0587866 |
| PDE10A | phosphodiesterase 10A | 0.0587452 |
| VIM | vimentin | 0.0567731 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.055766 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0553691 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0531327 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0524133 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0521495 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0503787 |
| RPS3 | ribosomal protein S3 | 0.0497777 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0480679 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0457418 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0446713 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0434282 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0427185 |
| OSMR | oncostatin M receptor | 0.0407382 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0407211 |
| WDR43 | WD repeat domain 43 | 0.0403455 |
| RPL23 | ribosomal protein L23 | 0.038063 |
| TAGLN2 | transgelin 2 | 0.037628 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0373354 |
| RPS12 | ribosomal protein S12 | 0.0372799 |
| GRAMD1B | GRAM domain containing 1B | 0.0371475 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.035569 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0343281 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.034097 |
| INTS6 | integrator complex subunit 6 | 0.0329079 |
| IGF1R | insulin-like growth factor 1 receptor | 0.032781 |
| MYOF | myoferlin | 0.0323097 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0314383 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0307126 |
| TUBA1B | tubulin, alpha 1b | 0.0301488 |
| FNDC3B | fibronectin type III domain containing 3B | 0.029665 |
| DST | dystonin | 0.0292532 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0290178 |
| PCBP2 | poly(rC) binding protein 2 | 0.0290133 |
| YBX3 | Y box binding protein 3 | 0.0290113 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.028447 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0281757 |
| JMJD1C | jumonji domain containing 1C | 0.0277374 |
| TPM3 | tropomyosin 3 | 0.027404 |
| ATP11A | ATPase, class VI, type 11A | 0.0273906 |
| LDHA | lactate dehydrogenase A | 0.0271102 |
| PTMS | parathymosin | 0.027097 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0270088 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0268882 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0268788 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0267715 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0267268 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0265694 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0261331 |
| BMP5 | bone morphogenetic protein 5 | 0.025947 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.025893 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0257656 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0257116 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0256826 |
| MSN | moesin | 0.0256229 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0255473 |
| DSPP | dentin sialophosphoprotein | 0.0252882 |
| RPS17 | ribosomal protein S17 | 0.0252794 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0251828 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.024398 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0242925 |
| PDLIM5 | PDZ and LIM domain 5 | 0.023882 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0238028 |
| PLSCR1 | phospholipid scramblase 1 | 0.023718 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0234698 |
| COPA | coatomer protein complex, subunit alpha | 0.0231158 |
| HOMER1 | homer scaffolding protein 1 | 0.0230172 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0228456 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.02278 |
| RPS19 | ribosomal protein S19 | 0.0227704 |
| WWOX | WW domain containing oxidoreductase | 0.022692 |
| STC1 | stanniocalcin 1 | 0.0226825 |
| PMP22 | peripheral myelin protein 22 | 0.0225647 |
| MAP1B | microtubule-associated protein 1B | 0.0224798 |
| RPS27 | ribosomal protein S27 | 0.0224754 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0223798 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.022296 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.022287 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.022232 |
| RPS4X | ribosomal protein S4, X-linked | 0.0220183 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0215862 |
| B2M | beta-2-microglobulin | 0.0215139 |
| MAP7 | microtubule-associated protein 7 | 0.0214819 |
| ATF6 | activating transcription factor 6 | 0.021391 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0209914 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0209631 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0208429 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0206339 |
| PLS3 | plastin 3 | 0.0205602 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0204812 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0204359 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.155369 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0826595 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0821175 |
| MT2A | metallothionein 2A | -0.0674902 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.059309 |
| PTMA | prothymosin, alpha | -0.0559554 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0505945 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0494231 |
| RPL35A | ribosomal protein L35a | -0.0485912 |
| EGR1 | early growth response 1 | -0.0468872 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0402524 |
| MCL1 | myeloid cell leukemia 1 | -0.0395807 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0390203 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0376258 |
| OGA | O-GlcNAcase | -0.0359372 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0357974 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0356435 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0353519 |
| RPS29 | ribosomal protein S29 | -0.034899 |
| ATXN2 | ataxin 2 | -0.0331047 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0311834 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0309739 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0307775 |
| IGF2 | insulin-like growth factor 2 | -0.0307439 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0303774 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0301175 |
| RRM2 | ribonucleotide reductase M2 | -0.0295767 |
| ZNF609 | zinc finger protein 609 | -0.0292917 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0288618 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0285568 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0284822 |
| PHIP | pleckstrin homology domain interacting protein | -0.0284439 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0278516 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0277328 |
| CANX | calnexin | -0.0275669 |
| UBTF | upstream binding transcription factor, RNA polymerase I | -0.0266173 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0262831 |
| RTN4 | reticulon 4 | -0.0262566 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0256957 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0256046 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0255051 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0254928 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0253388 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0253068 |
| CAVIN1 | caveolae associated protein 1 | -0.0251506 |
| PGK1 | phosphoglycerate kinase 1 | -0.0250316 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0249683 |
| NABP1 | nucleic acid binding protein 1 | -0.0243158 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0242677 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0241907 |
| SNX9 | sorting nexin 9 | -0.0240192 |
| STK4 | serine/threonine kinase 4 | -0.0239639 |
| CEP95 | centrosomal protein 95kDa | -0.0239589 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0237288 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0235298 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0234516 |
| BBX | bobby sox homolog (Drosophila) | -0.0232583 |
| TMEM165 | transmembrane protein 165 | -0.0232279 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.022874 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0226403 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0225782 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0225028 |
| TLK1 | tousled-like kinase 1 | -0.0224746 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0223524 |
| H3-3B | H3.3 histone B | -0.0221712 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0221613 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0220858 |
| RPS21 | ribosomal protein S21 | -0.0219851 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0219769 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0217269 |
| RPS15 | ribosomal protein S15 | -0.0216226 |
| MKI67 | marker of proliferation Ki-67 | -0.0215222 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0212971 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0212664 |
| NLGN1 | neuroligin 1 | -0.0212546 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0211934 |
| RBM39 | RNA binding motif protein 39 | -0.0211902 |
| RECQL | RecQ helicase-like | -0.021152 |
| MIS18BP1 | MIS18 binding protein 1 | -0.02099 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.0209797 |
| RPS27A | ribosomal protein S27a | -0.0208362 |
| ACTG1 | actin gamma 1 | -0.0208251 |
| RBM33 | RNA binding motif protein 33 | -0.0208152 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0207562 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0207345 |
| NUMB | numb homolog (Drosophila) | -0.0206646 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.020616 |
| AAK1 | AP2 associated kinase 1 | -0.020385 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0203727 |
| RASA2 | RAS p21 protein activator 2 | -0.0203709 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | -0.0203446 |
| MED13L | mediator complex subunit 13-like | -0.0201442 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0201157 |
| ICAM1 | intercellular adhesion molecule 1 | -0.019913 |
| CCNI | cyclin I | -0.0198713 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0196779 |
| RPL8 | ribosomal protein L8 | -0.0195606 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0195365 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0195169 |
| SPAG9 | sperm associated antigen 9 | -0.0195147 |
