| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bentamapimod perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bentamapimod_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.226742 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.101305 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0874714 |
| PDLIM5 | PDZ and LIM domain 5 | 0.080752 |
| MYOF | myoferlin | 0.0764524 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0708188 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.070058 |
| KYNU | kynureninase | 0.0626502 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0605661 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0581859 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0572886 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0564603 |
| CD109 | CD109 molecule | 0.0561567 |
| COL5A2 | collagen, type V, alpha 2 | 0.054974 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0532799 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0506731 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0491721 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0486179 |
| LSAMP | limbic system-associated membrane protein | 0.0483059 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0467071 |
| LDHA | lactate dehydrogenase A | 0.0460364 |
| PCBP2 | poly(rC) binding protein 2 | 0.0450714 |
| DNER | delta/notch-like EGF repeat containing | 0.0418037 |
| RPL23 | ribosomal protein L23 | 0.0405946 |
| RPL12 | ribosomal protein L12 | 0.0405603 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0401364 |
| POTEF | POTE ankyrin domain family, member F | 0.0397484 |
| MAP7 | microtubule-associated protein 7 | 0.0382605 |
| EZR | ezrin | 0.0377667 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0377615 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0372469 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0371371 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0365137 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0364723 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0358654 |
| CHL1 | cell adhesion molecule L1-like | 0.0350818 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.034466 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0338196 |
| ENO1 | enolase 1, (alpha) | 0.0318317 |
| SMAD2 | SMAD family member 2 | 0.0312222 |
| IRS2 | insulin receptor substrate 2 | 0.0306515 |
| RPS6 | ribosomal protein S6 | 0.0303433 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.0298278 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.029332 |
| RPS4X | ribosomal protein S4, X-linked | 0.0292574 |
| RACK1 | receptor for activated C kinase 1 | 0.0291959 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0285938 |
| EXT1 | exostosin glycosyltransferase 1 | 0.028115 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0275708 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0273196 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0270516 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0269452 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0268714 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0267759 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.026717 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.026687 |
| PTEN | phosphatase and tensin homolog | 0.0265158 |
| XYLT1 | xylosyltransferase I | 0.0264138 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0254506 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | 0.0252591 |
| RPLP0 | ribosomal protein, large, P0 | 0.0246886 |
| CD44 | CD44 molecule (Indian blood group) | 0.0246487 |
| NRXN3 | neurexin 3 | 0.0245819 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0240328 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0235048 |
| KRT19 | keratin 19, type I | 0.0233958 |
| RASAL2 | RAS protein activator like 2 | 0.0233758 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.022746 |
| RPL18 | ribosomal protein L18 | 0.022723 |
| CDH13 | cadherin 13 | 0.0225996 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0223957 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0223315 |
| RPS12 | ribosomal protein S12 | 0.0216618 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0215481 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0213561 |
| DST | dystonin | 0.0204027 |
| RPS3 | ribosomal protein S3 | 0.020346 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.020322 |
| RPS19 | ribosomal protein S19 | 0.020237 |
| MSN | moesin | 0.0199334 |
| RPS17 | ribosomal protein S17 | 0.0195844 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0195598 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0195027 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0190653 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0189458 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0188177 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0188147 |
| MAP1B | microtubule-associated protein 1B | 0.0187983 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0187719 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0187618 |
| SON | SON DNA binding protein | 0.0187081 |
| RPS27 | ribosomal protein S27 | 0.0185306 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0181244 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0181161 |
| RPL9 | ribosomal protein L9 | 0.0178118 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0178068 |
| ASTN2 | astrotactin 2 | 0.0175493 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0174924 |
| OXSR1 | oxidative stress responsive 1 | 0.0172857 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0170518 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.233513 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.189679 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.134404 |
| PTMA | prothymosin, alpha | -0.125742 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.103504 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0746281 |
| TMSB10 | thymosin beta 10 | -0.073113 |
| MCL1 | myeloid cell leukemia 1 | -0.0697384 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.069484 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0679677 |
| VCL | vinculin | -0.0613661 |
| GDA | guanine deaminase | -0.0591043 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0589641 |
| OGA | O-GlcNAcase | -0.0583355 |
| ACTG1 | actin gamma 1 | -0.0555048 |
| HLA-B | major histocompatibility complex, class I, B | -0.0529587 |
| EFNA5 | ephrin-A5 | -0.0479521 |
| CANX | calnexin | -0.047807 |
| PCBP3 | poly(rC) binding protein 3 | -0.0436428 |
| RPL35A | ribosomal protein L35a | -0.0401041 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0396292 |
| ASPH | aspartate beta-hydroxylase | -0.0394612 |
| RBM39 | RNA binding motif protein 39 | -0.0383653 |
| RTN1 | reticulon 1 | -0.038338 |
| STC1 | stanniocalcin 1 | -0.0376571 |
| RPS24 | ribosomal protein S24 | -0.0367085 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0363972 |
| GNAS | GNAS complex locus | -0.0363769 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0357064 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0351733 |
| NRCAM | neuronal cell adhesion molecule | -0.0346908 |
| SPAG9 | sperm associated antigen 9 | -0.0342784 |
| PGK1 | phosphoglycerate kinase 1 | -0.0330085 |
| SRPK2 | SRSF protein kinase 2 | -0.0329743 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.031603 |
| RTN4 | reticulon 4 | -0.0306679 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0295926 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0295915 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0294428 |
| CTSL | cathepsin L | -0.0290668 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0288526 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0282397 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0280251 |
| RPL13A | ribosomal protein L13a | -0.0279236 |
| RPL38 | ribosomal protein L38 | -0.0276884 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0275995 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0273315 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.026955 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0263974 |
| SMYD3 | SET and MYND domain containing 3 | -0.0263521 |
| RPS29 | ribosomal protein S29 | -0.0262712 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0258159 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0253563 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0252799 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0252436 |
| MT2A | metallothionein 2A | -0.025157 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0250767 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0244778 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.023777 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0237644 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0233844 |
| SRGN | serglycin | -0.0232951 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0232015 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0231141 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0230725 |
| FBXO11 | F-box protein 11 | -0.0229646 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0228851 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0226804 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0226062 |
| TPR | translocated promoter region, nuclear basket protein | -0.0225172 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0220544 |
| WDR45B | WD repeat domain 45B | -0.0219477 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0217409 |
| USP3 | ubiquitin specific peptidase 3 | -0.0214139 |
| RPL36A | ribosomal protein L36a | -0.0212204 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0209155 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0209051 |
| NDRG1 | N-myc downstream regulated 1 | -0.0206593 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0204767 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0204095 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0203616 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.020341 |
| RPS13 | ribosomal protein S13 | -0.0203314 |
| FTL | ferritin, light polypeptide | -0.0202723 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0201209 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0199321 |
| CALR | calreticulin | -0.0199004 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0198084 |
| IER3 | immediate early response 3 | -0.0196258 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0195813 |
| CUL4B | cullin 4B | -0.0194081 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0193609 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0191942 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0190204 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0190121 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0189062 |
| RPLP1 | ribosomal protein, large, P1 | -0.0187977 |
| RPL34 | ribosomal protein L34 | -0.0187238 |
| FUS | FUS RNA binding protein | -0.0186489 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0186304 |
