| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bentamapimod perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bentamapimod_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.17466 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.129828 |
| CTBP2 | C-terminal binding protein 2 | 0.127515 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.111781 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.109603 |
| RAD51B | RAD51 paralog B | 0.108509 |
| GOLGA4 | golgin A4 | 0.100698 |
| MTSS1 | metastasis suppressor 1 | 0.0973367 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0964542 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0945191 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0938295 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.091773 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0897019 |
| RPLP2 | ribosomal protein, large, P2 | 0.0850592 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0836305 |
| FAT1 | FAT atypical cadherin 1 | 0.0784274 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0773157 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0769394 |
| CDCP1 | CUB domain containing protein 1 | 0.0753793 |
| ZNF638 | zinc finger protein 638 | 0.0740498 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.0720797 |
| TES | testin LIM domain protein | 0.0716552 |
| RPL13A | ribosomal protein L13a | 0.0706004 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.067257 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0671596 |
| MYOF | myoferlin | 0.0666682 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0659913 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0656858 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0649143 |
| CREBBP | CREB binding protein | 0.0648926 |
| RASAL2 | RAS protein activator like 2 | 0.0647926 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0641547 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0634899 |
| SVIL | supervillin | 0.0607586 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0599563 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0596688 |
| GLIS3 | GLIS family zinc finger 3 | 0.0582969 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0581093 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.057919 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0575781 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0575418 |
| PHF3 | PHD finger protein 3 | 0.0567075 |
| ZNF292 | zinc finger protein 292 | 0.0564829 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0555384 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0545887 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0536044 |
| MED13 | mediator complex subunit 13 | 0.0534915 |
| PARD3 | par-3 family cell polarity regulator | 0.0532359 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0526882 |
| DEK | DEK proto-oncogene | 0.051828 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.051828 |
| RPL31 | ribosomal protein L31 | 0.0512564 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.051233 |
| HDLBP | high density lipoprotein binding protein | 0.0508327 |
| CCNY | cyclin Y | 0.050248 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0491802 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.04899 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0488599 |
| PTMA | prothymosin, alpha | 0.0477032 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0467083 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0464536 |
| EPCAM | epithelial cell adhesion molecule | 0.0463844 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0447579 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0445607 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0438763 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0432625 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0431471 |
| TCF12 | transcription factor 12 | 0.0425606 |
| HMGA1 | high mobility group AT-hook 1 | 0.0424394 |
| HMGA2 | high mobility group AT-hook 2 | 0.0422961 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0418691 |
| ATXN1 | ataxin 1 | 0.0406801 |
| SETD5 | SET domain containing 5 | 0.0399811 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0398223 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0394712 |
| LDHA | lactate dehydrogenase A | 0.0393358 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0391783 |
| RAB18 | RAB18, member RAS oncogene family | 0.0389399 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0378584 |
| NEMF | nuclear export mediator factor | 0.0373409 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0366953 |
| MAP4 | microtubule-associated protein 4 | 0.0362997 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0341352 |
| FLNB | filamin B, beta | 0.0341146 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0318872 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0307241 |
| RACK1 | receptor for activated C kinase 1 | 0.0305569 |
| USP34 | ubiquitin specific peptidase 34 | 0.0298827 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0296439 |
| WWC2 | WW and C2 domain containing 2 | 0.0294323 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0292756 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0287977 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.028685 |
| METTL15 | methyltransferase like 15 | 0.0277697 |
| BPTF | bromodomain PHD finger transcription factor | 0.0276724 |
| EGFR | epidermal growth factor receptor | 0.0273782 |
| CDK13 | cyclin-dependent kinase 13 | 0.0263376 |
| RPS23 | ribosomal protein S23 | 0.0255085 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0254558 |
| IGF2 | insulin-like growth factor 2 | 0.0244814 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMA4 | laminin, alpha 4 | -0.141255 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.139636 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.134782 |
| PDE10A | phosphodiesterase 10A | -0.110424 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.10115 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.101043 |
| FAM13A | family with sequence similarity 13, member A | -0.0996 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0982173 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0970187 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0953588 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0949815 |
| USP3 | ubiquitin specific peptidase 3 | -0.0945387 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0942181 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.093254 |
| RPL15 | ribosomal protein L15 | -0.092971 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0891325 |
| TXNRD1 | thioredoxin reductase 1 | -0.0889239 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0871652 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0860723 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.084036 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0839596 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.081135 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0802017 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0793408 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0779897 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0764254 |
| JMJD1C | jumonji domain containing 1C | -0.0754082 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0749055 |
| SBF2 | SET binding factor 2 | -0.0742423 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0737922 |
| FN1 | fibronectin 1 | -0.0734521 |
| PDE8A | phosphodiesterase 8A | -0.0728501 |
| CALU | calumenin | -0.0726075 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0723844 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.071116 |
| CLTC | clathrin, heavy chain (Hc) | -0.0709318 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0706508 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0701974 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.069921 |
| PKM | pyruvate kinase, muscle | -0.068836 |
| INHBA | inhibin, beta A | -0.0676221 |
| RUNX1 | runt-related transcription factor 1 | -0.0612313 |
| RPL11 | ribosomal protein L11 | -0.060668 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0599106 |
| STC1 | stanniocalcin 1 | -0.0597479 |
| SPAG9 | sperm associated antigen 9 | -0.0569166 |
| RPL12 | ribosomal protein L12 | -0.056009 |
| RTN4 | reticulon 4 | -0.0555614 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.055497 |
| PRELID2 | PRELI domain containing 2 | -0.0544144 |
| OGA | O-GlcNAcase | -0.0533672 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0531099 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0528388 |
| FTL | ferritin, light polypeptide | -0.0521981 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0515576 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0504175 |
| EZR | ezrin | -0.0488909 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0478051 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0477242 |
| GOLGB1 | golgin B1 | -0.04731 |
| RBM39 | RNA binding motif protein 39 | -0.0471308 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0466694 |
| RSF1 | remodeling and spacing factor 1 | -0.0463052 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0459138 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0458969 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0454803 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0434371 |
| RPL35A | ribosomal protein L35a | -0.042774 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0407841 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0400063 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0399625 |
| B2M | beta-2-microglobulin | -0.0394693 |
| FBXO11 | F-box protein 11 | -0.0386746 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0385617 |
| HLA-B | major histocompatibility complex, class I, B | -0.0385041 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0367491 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0365642 |
| TMSB10 | thymosin beta 10 | -0.0354905 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0354248 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0350468 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0349369 |
| ANXA2 | annexin A2 | -0.0347687 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0340922 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0338742 |
| ENO1 | enolase 1, (alpha) | -0.0335586 |
| SLTM | SAFB-like, transcription modulator | -0.0335124 |
| GNAS | GNAS complex locus | -0.0333654 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0328463 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0328203 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0318894 |
| DST | dystonin | -0.030094 |
| PGK1 | phosphoglycerate kinase 1 | -0.0289439 |
| RPS12 | ribosomal protein S12 | -0.0268093 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0266259 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0237863 |
| TJP1 | tight junction protein 1 | -0.0235562 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0235433 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0233677 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0230683 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0225397 |
