| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bentamapimod perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bentamapimod_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.11535 |
| FOXP2 | forkhead box P2 | 0.112585 |
| CADM2 | cell adhesion molecule 2 | 0.110206 |
| PEG10 | paternally expressed 10 | 0.10692 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0993071 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0955215 |
| MKI67 | marker of proliferation Ki-67 | 0.0930894 |
| POTEF | POTE ankyrin domain family, member F | 0.0846067 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0795928 |
| PCDH9 | protocadherin 9 | 0.0784295 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0752769 |
| HDAC9 | histone deacetylase 9 | 0.0739879 |
| ZNF608 | zinc finger protein 608 | 0.061553 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0588318 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0575916 |
| ZNF292 | zinc finger protein 292 | 0.0556846 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.0522694 |
| CDH19 | cadherin 19, type 2 | 0.0511896 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0487873 |
| XPO1 | exportin 1 | 0.0476443 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.047269 |
| PCDH18 | protocadherin 18 | 0.0464046 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0453578 |
| MEF2C | myocyte enhancer factor 2C | 0.0446459 |
| TENM2 | teneurin transmembrane protein 2 | 0.0438642 |
| COL5A2 | collagen, type V, alpha 2 | 0.0437811 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.043658 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0431116 |
| TCF12 | transcription factor 12 | 0.0420154 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0404306 |
| METAP2 | methionyl aminopeptidase 2 | 0.0383699 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0377718 |
| TENM3 | teneurin transmembrane protein 3 | 0.0369044 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0365641 |
| CDC14A | cell division cycle 14A | 0.035627 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0355097 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0352691 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0352531 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0350965 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0349958 |
| ATM | ATM serine/threonine kinase | 0.034812 |
| TOX | thymocyte selection-associated high mobility group box | 0.0337096 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0330411 |
| SSH2 | slingshot protein phosphatase 2 | 0.0330113 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0322199 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0319973 |
| RAD51B | RAD51 paralog B | 0.0319935 |
| KIF4A | kinesin family member 4A | 0.0318462 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0318221 |
| EGFR | epidermal growth factor receptor | 0.0317113 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0315202 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0311578 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0310338 |
| ZFHX4 | zinc finger homeobox 4 | 0.0306408 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0304835 |
| RPL23 | ribosomal protein L23 | 0.0303946 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0303563 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0302165 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 | 0.030094 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0295429 |
| PHF21A | PHD finger protein 21A | 0.0291611 |
| CENPF | centromere protein F, 350/400kDa | 0.0290505 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.028948 |
| MTDH | metadherin | 0.0283198 |
| TOGARAM1 | TOG array regulator of axonemal microtubules 1 | 0.0281605 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0275545 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0274611 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0270718 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0269308 |
| FILIP1 | filamin A interacting protein 1 | 0.0268121 |
| OSBPL6 | oxysterol binding protein-like 6 | 0.0267344 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0258002 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0257033 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0256607 |
| MYO10 | myosin X | 0.0254372 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0252012 |
| FST | follistatin | 0.0251973 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.025079 |
| RPLP0 | ribosomal protein, large, P0 | 0.0246513 |
| GPHN | gephyrin | 0.0241152 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0237414 |
| CORO1C | coronin, actin binding protein, 1C | 0.0233244 |
| SERTAD2 | SERTA domain containing 2 | 0.0231467 |
| TSEN15 | TSEN15 tRNA splicing endonuclease subunit | 0.0230756 |
| GSE1 | Gse1 coiled-coil protein | 0.0228376 |
| SEM1 | SEM1 26S proteasome subunit | 0.022837 |
| RAB22A | RAB22A, member RAS oncogene family | 0.0228117 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.022798 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0224851 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0223908 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.022374 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0222389 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.0221628 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.022012 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0219564 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0217699 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0217089 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 | 0.0216394 |
| RPS4X | ribosomal protein S4, X-linked | 0.0215393 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0215294 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.178701 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.17797 |
| PTMA | prothymosin, alpha | -0.125552 |
| VIM | vimentin | -0.123778 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0886751 |
| FNDC3B | fibronectin type III domain containing 3B | -0.082312 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0822571 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0769316 |
| ITGAV | integrin, alpha V | -0.0760816 |
| TMSB10 | thymosin beta 10 | -0.0748626 |
| AHNAK | AHNAK nucleoprotein | -0.0682803 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0665973 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0649167 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0601267 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0599586 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0589717 |
| PHIP | pleckstrin homology domain interacting protein | -0.0571403 |
| NRG1 | neuregulin 1 | -0.0564588 |
| FAM171B | family with sequence similarity 171, member B | -0.0560638 |
| RPL35A | ribosomal protein L35a | -0.0551865 |
| RTN4 | reticulon 4 | -0.0518725 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0515439 |
| TPR | translocated promoter region, nuclear basket protein | -0.0508292 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0489904 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0483637 |
| NEBL | nebulette | -0.0481473 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0476258 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0462896 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.044554 |
| H1-0 | H1.0 linker histone | -0.0430359 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0424559 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0424131 |
| RPLP1 | ribosomal protein, large, P1 | -0.0422669 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0412948 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0412123 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0406404 |
| THOC2 | THO complex 2 | -0.0396945 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0390079 |
| RPL34 | ribosomal protein L34 | -0.0389546 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0388645 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0388311 |
| RPS8 | ribosomal protein S8 | -0.0387616 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0385587 |
| RBM39 | RNA binding motif protein 39 | -0.0383478 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0379916 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0365163 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0364725 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0361151 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0354934 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0352797 |
| MAP4 | microtubule-associated protein 4 | -0.0347832 |
| RAI1 | retinoic acid induced 1 | -0.0346177 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0342523 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0342475 |
| EMP1 | epithelial membrane protein 1 | -0.0341963 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0340991 |
| RPL19 | ribosomal protein L19 | -0.0337234 |
| CANX | calnexin | -0.0335141 |
| SPAG9 | sperm associated antigen 9 | -0.0332878 |
| PGK1 | phosphoglycerate kinase 1 | -0.0331679 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | -0.0327388 |
| SETD5 | SET domain containing 5 | -0.0324857 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0318014 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0314723 |
| NOP58 | NOP58 ribonucleoprotein | -0.0314645 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0307393 |
| SRP54 | signal recognition particle 54kDa | -0.03043 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0303818 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0300644 |
| BBX | bobby sox homolog (Drosophila) | -0.029867 |
| APP | amyloid beta (A4) precursor protein | -0.0297964 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0297226 |
| PKM | pyruvate kinase, muscle | -0.0297047 |
| RLF | rearranged L-myc fusion | -0.0296394 |
| S100A10 | S100 calcium binding protein A10 | -0.0296071 |
| RPL37 | ribosomal protein L37 | -0.0294842 |
| DENND5B | DENN/MADD domain containing 5B | -0.0293079 |
| NTM | neurotrimin | -0.0292044 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0286157 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0285963 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0285852 |
| MED13L | mediator complex subunit 13-like | -0.0281614 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0280681 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0278614 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0277751 |
| RPS24 | ribosomal protein S24 | -0.0276105 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0274931 |
| RPS10 | ribosomal protein S10 | -0.0274822 |
| RPS21 | ribosomal protein S21 | -0.0274716 |
| RPL31 | ribosomal protein L31 | -0.0273393 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0273184 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0272262 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0270417 |
| CLTC | clathrin, heavy chain (Hc) | -0.0269765 |
| ACTG1 | actin gamma 1 | -0.0267986 |
| RPL6 | ribosomal protein L6 | -0.0264866 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0264207 |
| RIGI | RNA sensor RIG-I | -0.0263982 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0263352 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0262267 |
