| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bentamapimod perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bentamapimod_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.153935 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.112698 |
| EZR | ezrin | 0.0615516 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0597647 |
| EGFR | epidermal growth factor receptor | 0.0577705 |
| POTEF | POTE ankyrin domain family, member F | 0.0556308 |
| ZNF608 | zinc finger protein 608 | 0.0545781 |
| PDGFC | platelet derived growth factor C | 0.0481033 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.041485 |
| HDAC9 | histone deacetylase 9 | 0.0412519 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.039214 |
| PCBP2 | poly(rC) binding protein 2 | 0.038793 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0381671 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0373409 |
| B2M | beta-2-microglobulin | 0.0330607 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0321456 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0290719 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0287526 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0285599 |
| BRD2 | bromodomain containing 2 | 0.0285166 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0276905 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0276361 |
| TJP1 | tight junction protein 1 | 0.02741 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0270021 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0268661 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0268544 |
| ANXA1 | annexin A1 | 0.0264763 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0257306 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0250338 |
| LONRF2 | LON peptidase N-terminal domain and ring finger 2 | 0.0245011 |
| JUN | jun proto-oncogene | 0.024116 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.02387 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0234776 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.022948 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.022509 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0223794 |
| DSTN | destrin (actin depolymerizing factor) | 0.0221626 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0219211 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0215113 |
| SGMS2 | sphingomyelin synthase 2 | 0.0212468 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.021203 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0212021 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0204901 |
| LDHB | lactate dehydrogenase B | 0.0203852 |
| DIAPH1 | diaphanous-related formin 1 | 0.0201798 |
| PRDX2 | peroxiredoxin 2 | 0.0201407 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0199702 |
| MACROD2 | MACRO domain containing 2 | 0.0199596 |
| SON | SON DNA binding protein | 0.0199118 |
| RPL23 | ribosomal protein L23 | 0.019898 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0190326 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0190283 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.018689 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.018662 |
| CLU | clusterin | 0.0186504 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0186429 |
| RPL21 | ribosomal protein L21 | 0.018576 |
| PLK2 | polo-like kinase 2 | 0.0181909 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0180689 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.018011 |
| RPL18 | ribosomal protein L18 | 0.0177247 |
| ATF4 | activating transcription factor 4 | 0.0176524 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0175145 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0174797 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0173586 |
| LDHA | lactate dehydrogenase A | 0.0171928 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.0171824 |
| RPS3 | ribosomal protein S3 | 0.0171128 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0162187 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0161327 |
| VMP1 | vacuole membrane protein 1 | 0.0160478 |
| TMF1 | TATA element modulatory factor 1 | 0.0159309 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0158833 |
| RPS12 | ribosomal protein S12 | 0.0157875 |
| RPS8 | ribosomal protein S8 | 0.0157012 |
| FNIP1 | folliculin interacting protein 1 | 0.0155383 |
| RPS6 | ribosomal protein S6 | 0.0154913 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0153912 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0153207 |
| RPS26 | ribosomal protein S26 | 0.0153085 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0152399 |
| CORO1C | coronin, actin binding protein, 1C | 0.0151946 |
| USP47 | ubiquitin specific peptidase 47 | 0.0150653 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0150057 |
| DAPK3 | death-associated protein kinase 3 | 0.0149811 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0149351 |
| RPL36 | ribosomal protein L36 | 0.0148955 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.014889 |
| KIF5C | kinesin family member 5C | 0.0148615 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0147725 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0145992 |
| RPS2 | ribosomal protein S2 | 0.0145356 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | 0.0145244 |
| UBXN4 | UBX domain protein 4 | 0.0144901 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0144699 |
| COG6 | component of oligomeric golgi complex 6 | 0.0142901 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0140212 |
| ZNF148 | zinc finger protein 148 | 0.0139598 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0137746 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0136333 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.302609 |
| AHNAK | AHNAK nucleoprotein | -0.138277 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.117469 |
| BMP10 | bone morphogenetic protein 10 | -0.117434 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.116764 |
| VCL | vinculin | -0.115742 |
| TMSB4X | thymosin beta 4, X-linked | -0.113941 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.110772 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.104423 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.104035 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.100769 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0988262 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0854571 |
| FLNB | filamin B, beta | -0.0830737 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0714694 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0701315 |
| NBEA | neurobeachin | -0.0691002 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0658295 |
| ACTG1 | actin gamma 1 | -0.0652303 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.059684 |
| BMP2K | BMP2 inducible kinase | -0.0547244 |
| RPL35A | ribosomal protein L35a | -0.0544865 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0519472 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0503207 |
| MYO5C | myosin VC | -0.049922 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0499043 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0492514 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0489419 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0485459 |
| NAV2 | neuron navigator 2 | -0.0479776 |
| CCND1 | cyclin D1 | -0.0469327 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0456212 |
| NFIA | nuclear factor I/A | -0.0452365 |
| GLI2 | GLI family zinc finger 2 | -0.0443144 |
| PYGB | phosphorylase, glycogen; brain | -0.0438412 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0428853 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0426295 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.04177 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0412671 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0411676 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0386499 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0385331 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0381248 |
| RPL34 | ribosomal protein L34 | -0.0379023 |
| S100A6 | S100 calcium binding protein A6 | -0.0377509 |
| PGK1 | phosphoglycerate kinase 1 | -0.037335 |
| CUX1 | cut-like homeobox 1 | -0.0369954 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0349109 |
| GLI3 | GLI family zinc finger 3 | -0.0342197 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0333094 |
| RPS27A | ribosomal protein S27a | -0.0330982 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0330743 |
| FOXP1 | forkhead box P1 | -0.0323942 |
| GNAS | GNAS complex locus | -0.0323377 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0320229 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0317829 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0317761 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0317313 |
| MSI2 | musashi RNA-binding protein 2 | -0.0316642 |
| S100A4 | S100 calcium binding protein A4 | -0.0316586 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0313046 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0309018 |
| NEBL | nebulette | -0.030793 |
| PARD3 | par-3 family cell polarity regulator | -0.0307769 |
| APP | amyloid beta (A4) precursor protein | -0.0304683 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0304351 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0299918 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0297744 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0296012 |
| MKI67 | marker of proliferation Ki-67 | -0.0294646 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0292579 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0291697 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0291395 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0287488 |
| ZNF438 | zinc finger protein 438 | -0.0286962 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0283069 |
| DENND1A | DENN/MADD domain containing 1A | -0.0280672 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0278041 |
| LOC112694756 | uncharaterized LOC112694756 | -0.027598 |
| RRBP1 | ribosome binding protein 1 | -0.0266254 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0262655 |
| RBM39 | RNA binding motif protein 39 | -0.0262483 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0261819 |
| FUS | FUS RNA binding protein | -0.026081 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.025923 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0255794 |
| RPLP2 | ribosomal protein, large, P2 | -0.025569 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0255332 |
| S100A10 | S100 calcium binding protein A10 | -0.0254784 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0254047 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0253306 |
| RPS24 | ribosomal protein S24 | -0.0252912 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0250306 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0249909 |
| RPL4 | ribosomal protein L4 | -0.024989 |
| RPL26 | ribosomal protein L26 | -0.024826 |
| GPATCH8 | G patch domain containing 8 | -0.0244158 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0240609 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0240211 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.024018 |
