| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bentamapimod perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bentamapimod_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.131544 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.122654 |
| HDAC9 | histone deacetylase 9 | 0.103678 |
| LDHA | lactate dehydrogenase A | 0.0970579 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0881146 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0846709 |
| VIM | vimentin | 0.0631112 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.061269 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0601373 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0550093 |
| MYOF | myoferlin | 0.0473825 |
| B2M | beta-2-microglobulin | 0.0471792 |
| RPL23 | ribosomal protein L23 | 0.0454621 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.045212 |
| NAV2 | neuron navigator 2 | 0.044973 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0426557 |
| MORF4L2 | mortality factor 4 like 2 | 0.0425902 |
| FNIP1 | folliculin interacting protein 1 | 0.041737 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0405436 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0397856 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0397311 |
| RPS12 | ribosomal protein S12 | 0.0384615 |
| SFTPA2 | surfactant protein A2 | 0.0383896 |
| SQSTM1 | sequestosome 1 | 0.0382782 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0380308 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0377048 |
| RND3 | Rho family GTPase 3 | 0.0370139 |
| RPS8 | ribosomal protein S8 | 0.0365701 |
| RPS3 | ribosomal protein S3 | 0.0361825 |
| HLA-A | major histocompatibility complex, class I, A | 0.0360891 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0353359 |
| ENO1 | enolase 1, (alpha) | 0.0352425 |
| VCAN | versican | 0.0336298 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0329214 |
| ANXA2 | annexin A2 | 0.0319263 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0311213 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0310279 |
| GOLGB1 | golgin B1 | 0.0302741 |
| INTS6 | integrator complex subunit 6 | 0.0298787 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0294384 |
| RPLP0 | ribosomal protein, large, P0 | 0.0292283 |
| RPL12 | ribosomal protein L12 | 0.0292038 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0291343 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0286735 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0283888 |
| PLIN2 | perilipin 2 | 0.0283656 |
| SP100 | SP100 nuclear antigen | 0.0281004 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0280212 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0279629 |
| RPL26 | ribosomal protein L26 | 0.027619 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0274305 |
| RPL37A | ribosomal protein L37a | 0.0259781 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0259346 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0258217 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0256812 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0256479 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0255941 |
| IPO7 | importin 7 | 0.0255682 |
| ZNF292 | zinc finger protein 292 | 0.0251821 |
| AHR | aryl hydrocarbon receptor | 0.0251272 |
| KYNU | kynureninase | 0.025064 |
| RACK1 | receptor for activated C kinase 1 | 0.0246164 |
| CDH13 | cadherin 13 | 0.0241657 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0241159 |
| BRD2 | bromodomain containing 2 | 0.0240831 |
| HLA-E | major histocompatibility complex, class I, E | 0.0240746 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0237458 |
| SERINC1 | serine incorporator 1 | 0.0235408 |
| ASPH | aspartate beta-hydroxylase | 0.0227094 |
| TMSB4X | thymosin beta 4, X-linked | 0.0226769 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.022552 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0225394 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0224762 |
| JMJD1C | jumonji domain containing 1C | 0.0223411 |
| TLE4 | transducin-like enhancer of split 4 | 0.0223327 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0222145 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0221501 |
| PHF3 | PHD finger protein 3 | 0.02185 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0214735 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0214676 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0214084 |
| CD44 | CD44 molecule (Indian blood group) | 0.0213716 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0212334 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0210567 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0207713 |
| MAP1B | microtubule-associated protein 1B | 0.020595 |
| CREBRF | CREB3 regulatory factor | 0.0205767 |
| RPS17 | ribosomal protein S17 | 0.0205529 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0204207 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0203994 |
| IER3 | immediate early response 3 | 0.0202525 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0201761 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.020033 |
| PGM3 | phosphoglucomutase 3 | 0.0199925 |
| FMNL2 | formin-like 2 | 0.0199353 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0199072 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0199018 |
| SYNJ2 | synaptojanin 2 | 0.0197578 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0197004 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0196587 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0689144 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0670931 |
| FRMD4A | FERM domain containing 4A | -0.0646986 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0581064 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.057592 |
| GLIS3 | GLIS family zinc finger 3 | -0.0564742 |
| TMSB10 | thymosin beta 10 | -0.0502238 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0458966 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0399342 |
| HLA-B | major histocompatibility complex, class I, B | -0.0398564 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0357238 |
| RTN4 | reticulon 4 | -0.0341967 |
| C3 | complement component 3 | -0.0307068 |
| COL1A1 | collagen, type I, alpha 1 | -0.0299097 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0298512 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0289097 |
| NDRG1 | N-myc downstream regulated 1 | -0.0285247 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0279162 |
| CCNL1 | cyclin L1 | -0.0251193 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0250786 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0247127 |
| PTMA | prothymosin, alpha | -0.0246983 |
| FN1 | fibronectin 1 | -0.0238091 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0236847 |
| TPM4 | tropomyosin 4 | -0.0236027 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0227543 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0224142 |
| EGR1 | early growth response 1 | -0.0218734 |
| VMP1 | vacuole membrane protein 1 | -0.0217566 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0215108 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0214917 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.02133 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0211927 |
| MAP4 | microtubule-associated protein 4 | -0.0210173 |
| TXNIP | thioredoxin interacting protein | -0.0200566 |
| CLMP | CXADR-like membrane protein | -0.019695 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0193963 |
| ARF4 | ADP-ribosylation factor 4 | -0.0191819 |
| CDCP1 | CUB domain containing protein 1 | -0.0189302 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0186997 |
| TMEM41B | transmembrane protein 41B | -0.0181976 |
| COL1A2 | collagen, type I, alpha 2 | -0.0180558 |
| RAI14 | retinoic acid induced 14 | -0.0177947 |
| NABP1 | nucleic acid binding protein 1 | -0.0177093 |
| S100A9 | S100 calcium binding protein A9 | -0.0176696 |
| CTSD | cathepsin D | -0.0176647 |
| PDE10A | phosphodiesterase 10A | -0.0174473 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0174069 |
| DUSP5 | dual specificity phosphatase 5 | -0.0171915 |
| ACTG1 | actin gamma 1 | -0.0169766 |
| SEPTIN9 | septin 9 | -0.0168056 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0161681 |
| GGNBP2 | gametogenetin binding protein 2 | -0.016028 |
| PRR16 | proline rich 16 | -0.015928 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0154549 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0154227 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.0154067 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0148709 |
| WASF2 | WAS protein family, member 2 | -0.0146793 |
| DIAPH2 | diaphanous-related formin 2 | -0.014438 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0143403 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0141289 |
| SRPK2 | SRSF protein kinase 2 | -0.0139637 |
| CDK19 | cyclin-dependent kinase 19 | -0.0139587 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0139249 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.013839 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0137712 |
| TAPBP | TAP binding protein (tapasin) | -0.0136243 |
| PARD3 | par-3 family cell polarity regulator | -0.0135869 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0133412 |
| RPL35A | ribosomal protein L35a | -0.0133214 |
| PHF21A | PHD finger protein 21A | -0.0131945 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0131065 |
| NAV1 | neuron navigator 1 | -0.0129973 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0129012 |
| CEP95 | centrosomal protein 95kDa | -0.0128849 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0127954 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0126711 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.012622 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0124236 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0121229 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0120617 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0120229 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0118935 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0117435 |
| RNF24 | ring finger protein 24 | -0.0117331 |
| WDR44 | WD repeat domain 44 | -0.0116798 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0116564 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0116457 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0116433 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0116391 |
| EPHA6 | EPH receptor A6 | -0.0116359 |
| RNF213 | ring finger protein 213 | -0.0116047 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0114994 |
| ATP11B | ATPase, class VI, type 11B | -0.0112737 |
| HMGA1 | high mobility group AT-hook 1 | -0.0112383 |
| NRP1 | neuropilin 1 | -0.0111987 |
| RBM39 | RNA binding motif protein 39 | -0.0111858 |
| IL6 | interleukin 6 | -0.0110839 |
| FLNB | filamin B, beta | -0.0110694 |
