| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bentamapimod perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bentamapimod_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.239717 |
| MT2A | metallothionein 2A | 0.213513 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.204416 |
| VIM | vimentin | 0.137174 |
| HLA-A | major histocompatibility complex, class I, A | 0.125757 |
| CD44 | CD44 molecule (Indian blood group) | 0.120029 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.11335 |
| FTL | ferritin, light polypeptide | 0.100108 |
| ENO1 | enolase 1, (alpha) | 0.089092 |
| CALR | calreticulin | 0.0780879 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0738053 |
| LDHA | lactate dehydrogenase A | 0.069304 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0683344 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0682181 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0577736 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0562709 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.055784 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0540819 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0532218 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0527382 |
| RPL37A | ribosomal protein L37a | 0.0492621 |
| STC1 | stanniocalcin 1 | 0.0474651 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0464086 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0445979 |
| PTN | pleiotrophin | 0.0424815 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0423338 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0406768 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0403728 |
| TMSB10 | thymosin beta 10 | 0.0403182 |
| POTEF | POTE ankyrin domain family, member F | 0.0402502 |
| ADM | adrenomedullin | 0.0395324 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0388012 |
| HLA-B | major histocompatibility complex, class I, B | 0.0386668 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0380931 |
| SEPTIN7 | septin 7 | 0.0379822 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0379094 |
| RPL11 | ribosomal protein L11 | 0.0378865 |
| ANXA2 | annexin A2 | 0.0378762 |
| RPS8 | ribosomal protein S8 | 0.0373356 |
| RACK1 | receptor for activated C kinase 1 | 0.0370835 |
| UBC | ubiquitin C | 0.0369535 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0364937 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0364014 |
| S100A10 | S100 calcium binding protein A10 | 0.0357655 |
| FAM13A | family with sequence similarity 13, member A | 0.0354503 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0351379 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0344934 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0342857 |
| CLIC4 | chloride intracellular channel 4 | 0.0332568 |
| S100A6 | S100 calcium binding protein A6 | 0.0331537 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0323483 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0315504 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0309597 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0305311 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0302668 |
| BRD2 | bromodomain containing 2 | 0.0302153 |
| HLA-C | major histocompatibility complex, class I, C | 0.0299247 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0298957 |
| CAVIN1 | caveolae associated protein 1 | 0.0298465 |
| ECE1 | endothelin converting enzyme 1 | 0.029844 |
| MAP1B | microtubule-associated protein 1B | 0.0295101 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0292215 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.029188 |
| DSTN | destrin (actin depolymerizing factor) | 0.0289526 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0288211 |
| CANX | calnexin | 0.0287978 |
| RPS12 | ribosomal protein S12 | 0.028625 |
| RPL23 | ribosomal protein L23 | 0.0284031 |
| RPL12 | ribosomal protein L12 | 0.0275739 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0273748 |
| ANO6 | anoctamin 6 | 0.0272672 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0270455 |
| SYNJ2 | synaptojanin 2 | 0.0269671 |
| GLG1 | golgi glycoprotein 1 | 0.026586 |
| ZNF395 | zinc finger protein 395 | 0.0263281 |
| VDAC1 | voltage-dependent anion channel 1 | 0.026198 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0261466 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0261265 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0260139 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0259937 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0259543 |
| PKM | pyruvate kinase, muscle | 0.0254345 |
| CENPF | centromere protein F, 350/400kDa | 0.0253527 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0253363 |
| FNIP1 | folliculin interacting protein 1 | 0.0250265 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0249662 |
| RPLP2 | ribosomal protein, large, P2 | 0.0247848 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0247503 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0247142 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0245105 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0243434 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0243327 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0242537 |
| BSG | basigin (Ok blood group) | 0.0241328 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0240654 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0240448 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.023834 |
| SP100 | SP100 nuclear antigen | 0.023578 |
| RPS14 | ribosomal protein S14 | 0.0233968 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | 0.0233395 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.133249 |
| CDH13 | cadherin 13 | -0.0798254 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0512498 |
| VCL | vinculin | -0.0490021 |
| HMGA2 | high mobility group AT-hook 2 | -0.045568 |
| COL6A2 | collagen, type VI, alpha 2 | -0.043015 |
| EFNA5 | ephrin-A5 | -0.0428277 |
| COL5A1 | collagen, type V, alpha 1 | -0.0410321 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0381632 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0380302 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0370733 |
| LOXL2 | lysyl oxidase-like 2 | -0.0369559 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.035241 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0345954 |
| RBM39 | RNA binding motif protein 39 | -0.033923 |
| OGA | O-GlcNAcase | -0.0332617 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0324454 |
| SRPK2 | SRSF protein kinase 2 | -0.0323553 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.032076 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0317653 |
| USP34 | ubiquitin specific peptidase 34 | -0.031691 |
| INHBA | inhibin, beta A | -0.0308528 |
| RASAL2 | RAS protein activator like 2 | -0.0297332 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.028329 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0281966 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.028151 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0274885 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0266307 |
| EXOC4 | exocyst complex component 4 | -0.0265425 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0259141 |
| CUL3 | cullin 3 | -0.0249559 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0249385 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0248471 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0232309 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0230402 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0227322 |
| NKTR | natural killer cell triggering receptor | -0.0227301 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0226812 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0224297 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0222879 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0222347 |
| ETV6 | ets variant 6 | -0.0221908 |
| RBM25 | RNA binding motif protein 25 | -0.0221215 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0220672 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0218888 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0218387 |
| RAI14 | retinoic acid induced 14 | -0.0217231 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0215207 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0214733 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.0212397 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0210968 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0210728 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0208869 |
| NABP1 | nucleic acid binding protein 1 | -0.0208447 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0205397 |
| OSMR | oncostatin M receptor | -0.0203977 |
| VMP1 | vacuole membrane protein 1 | -0.0203796 |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 | -0.0200668 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0200075 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.019937 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0199111 |
| YEATS2 | YEATS domain containing 2 | -0.0198256 |
| RBM33 | RNA binding motif protein 33 | -0.0197337 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0196675 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0196219 |
| KRIT1 | KRIT1, ankyrin repeat containing | -0.0195678 |
| FUS | FUS RNA binding protein | -0.019507 |
| TCF12 | transcription factor 12 | -0.0194821 |
| MED15 | mediator complex subunit 15 | -0.0193216 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0192605 |
| CARD16 | caspase recruitment domain family, member 16 | -0.019249 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0191901 |
| MCU | mitochondrial calcium uniporter | -0.01906 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0190516 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0189766 |
| STK17A | serine/threonine kinase 17a | -0.0188661 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0188477 |
| SUCO | SUN domain containing ossification factor | -0.0186502 |
| WDR33 | WD repeat domain 33 | -0.0185939 |
| ZHX3 | zinc fingers and homeoboxes 3 | -0.0184537 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0184186 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0183857 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0182856 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0181196 |
| ZNF644 | zinc finger protein 644 | -0.0180111 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0179737 |
| WTAP | Wilms tumor 1 associated protein | -0.017773 |
| PANK2 | pantothenate kinase 2 | -0.0177329 |
| AOPEP | aminopeptidase O (putative) | -0.0176896 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0176788 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0176356 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0176137 |
| COL5A2 | collagen, type V, alpha 2 | -0.0176004 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0173548 |
| PYGL | phosphorylase, glycogen, liver | -0.0173224 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0172693 |
| EP300 | E1A binding protein p300 | -0.0172374 |
| GLIS3 | GLIS family zinc finger 3 | -0.0171942 |
| TPD52L2 | tumor protein D52-like 2 | -0.0171798 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.017162 |
