| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bentamapimod perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bentamapimod_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.137372 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.12988 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.103508 |
| INTS6 | integrator complex subunit 6 | 0.0933855 |
| FMNL2 | formin-like 2 | 0.0706021 |
| ASPH | aspartate beta-hydroxylase | 0.0672395 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.064666 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0644709 |
| CD44 | CD44 molecule (Indian blood group) | 0.0628847 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0628785 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0625136 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0601582 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0574516 |
| LDHA | lactate dehydrogenase A | 0.0565969 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0559412 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0537272 |
| ATG7 | autophagy related 7 | 0.0524542 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.051786 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0516362 |
| PKM | pyruvate kinase, muscle | 0.0509318 |
| EGFR | epidermal growth factor receptor | 0.0499624 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0490288 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0472034 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.045687 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0443444 |
| RAD51B | RAD51 paralog B | 0.0442364 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0435654 |
| EXT1 | exostosin glycosyltransferase 1 | 0.042862 |
| GOLGB1 | golgin B1 | 0.0427579 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0422494 |
| HPCAL1 | hippocalcin-like 1 | 0.0417366 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0413967 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0408013 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0396369 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0393702 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.03845 |
| RPS17 | ribosomal protein S17 | 0.0380812 |
| SP100 | SP100 nuclear antigen | 0.0380317 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0366678 |
| RPL37 | ribosomal protein L37 | 0.0357938 |
| SMAD3 | SMAD family member 3 | 0.035292 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0350342 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0348521 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0347427 |
| RPL37A | ribosomal protein L37a | 0.0336566 |
| BRD2 | bromodomain containing 2 | 0.0334674 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0333075 |
| SCFD1 | sec1 family domain containing 1 | 0.0332366 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.032972 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0327936 |
| KLHL29 | kelch-like family member 29 | 0.0327355 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0318609 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.03186 |
| SVIL | supervillin | 0.0311468 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0309683 |
| RIGI | RNA sensor RIG-I | 0.0309376 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0304264 |
| PHF3 | PHD finger protein 3 | 0.0296617 |
| EGR1 | early growth response 1 | 0.0296328 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0292543 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0287737 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0284621 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0284048 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0283898 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0282679 |
| CDCP1 | CUB domain containing protein 1 | 0.027923 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0278787 |
| RPS20 | ribosomal protein S20 | 0.0278765 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0278365 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0276698 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0275681 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0275392 |
| SMIM14 | small integral membrane protein 14 | 0.0275165 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.027475 |
| SIK3 | SIK family kinase 3 | 0.0269446 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0268081 |
| PTK2 | protein tyrosine kinase 2 | 0.0268051 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0266172 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0265946 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0265511 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0264021 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0260211 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0259102 |
| ERBIN | erbb2 interacting protein | 0.0258916 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.025791 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0255436 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0251415 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0251405 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0251367 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0250958 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0249141 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0249105 |
| RAI14 | retinoic acid induced 14 | 0.0249075 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0248686 |
| RPL23 | ribosomal protein L23 | 0.0248149 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0245591 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0245129 |
| MATR3 | matrin 3 | 0.0244962 |
| RPL35 | ribosomal protein L35 | 0.0244913 |
| RCOR1 | REST corepressor 1 | 0.024475 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0998335 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0638017 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0629901 |
| SNX14 | sorting nexin 14 | -0.062284 |
| RBM39 | RNA binding motif protein 39 | -0.0619118 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0618493 |
| DEK | DEK proto-oncogene | -0.0615657 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0580802 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0554645 |
| SPAG9 | sperm associated antigen 9 | -0.0499111 |
| CANX | calnexin | -0.049101 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0481803 |
| NUP58 | nucleoporin 58 | -0.0480827 |
| YBX3 | Y box binding protein 3 | -0.0479227 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0476233 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0474955 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0472152 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0471521 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0468885 |
| TMSB10 | thymosin beta 10 | -0.0468185 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0467139 |
| PHIP | pleckstrin homology domain interacting protein | -0.0464389 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.045845 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0452185 |
| PTMA | prothymosin, alpha | -0.0444166 |
| ANLN | anillin, actin binding protein | -0.0441273 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0439113 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0424139 |
| OGA | O-GlcNAcase | -0.0423414 |
| JMJD1C | jumonji domain containing 1C | -0.0406188 |
| GOLT1B | golgi transport 1B | -0.0392465 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0392125 |
| MKI67 | marker of proliferation Ki-67 | -0.0387646 |
| DIAPH3 | diaphanous-related formin 3 | -0.0379354 |
| USP3 | ubiquitin specific peptidase 3 | -0.0378762 |
| UBAC2 | UBA domain containing 2 | -0.0372002 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0365583 |
| IER3 | immediate early response 3 | -0.0352003 |
| NF1 | neurofibromin 1 | -0.0344151 |
| CDK19 | cyclin-dependent kinase 19 | -0.034289 |
| RTN4 | reticulon 4 | -0.0338148 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0332259 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0324906 |
| SGO2 | shugoshin 2 | -0.0320827 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0320189 |
| LMO7 | LIM domain 7 | -0.0319081 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0317753 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0317053 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0316291 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0316242 |
| ZFR | zinc finger RNA binding protein | -0.0312593 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0311957 |
| MORF4L1 | mortality factor 4 like 1 | -0.0309607 |
| RPS11 | ribosomal protein S11 | -0.0308328 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0307403 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0303391 |
| CENPF | centromere protein F, 350/400kDa | -0.0302796 |
| PARD3 | par-3 family cell polarity regulator | -0.0301387 |
| GOLGA2 | golgin A2 | -0.0299171 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0297888 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0297678 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0292658 |
| FMN1 | formin 1 | -0.0292236 |
| RSF1 | remodeling and spacing factor 1 | -0.0291897 |
| CLINT1 | clathrin interactor 1 | -0.0290775 |
| RPS13 | ribosomal protein S13 | -0.0289689 |
| S100A9 | S100 calcium binding protein A9 | -0.0288676 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0287963 |
| ETF1 | eukaryotic translation termination factor 1 | -0.0285493 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0283755 |
| FAM3C | family with sequence similarity 3, member C | -0.0283507 |
| S100A6 | S100 calcium binding protein A6 | -0.028269 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0281877 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0280422 |
| ZFP91 | ZFP91 zinc finger protein | -0.0280165 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit | -0.027891 |
| ECT2 | epithelial cell transforming 2 | -0.0273239 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | -0.0272565 |
| HELZ | helicase with zinc finger | -0.0270891 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0269089 |
| RPS19 | ribosomal protein S19 | -0.0268712 |
| PDCD10 | programmed cell death 10 | -0.0268485 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0267597 |
| NUMA1 | nuclear mitotic apparatus protein 1 | -0.0266443 |
| FNBP1 | formin binding protein 1 | -0.026594 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0265773 |
| MORF4L2 | mortality factor 4 like 2 | -0.0265492 |
| PLEKHA8 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 | -0.026354 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0263421 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0263224 |
| CUL3 | cullin 3 | -0.0263164 |
| RBM33 | RNA binding motif protein 33 | -0.026229 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0262143 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0261982 |
| ZNF292 | zinc finger protein 292 | -0.0261317 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0261296 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0260056 |
| MEMO1 | mediator of cell motility 1 | -0.0257972 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.0255772 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0255425 |
