| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bentamapimod perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bentamapimod_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.112735 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0761751 |
| B2M | beta-2-microglobulin | 0.0662995 |
| FAT1 | FAT atypical cadherin 1 | 0.0594452 |
| RASAL2 | RAS protein activator like 2 | 0.0474331 |
| MYOF | myoferlin | 0.046876 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0436066 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0430606 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0424543 |
| SFTPA2 | surfactant protein A2 | 0.0416673 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0416567 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0374719 |
| DSTN | destrin (actin depolymerizing factor) | 0.0374359 |
| FAM13A | family with sequence similarity 13, member A | 0.0365867 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0357227 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0340085 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0334204 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.030094 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0299682 |
| SVIL | supervillin | 0.0294433 |
| SIK3 | SIK family kinase 3 | 0.0282803 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0279923 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0279749 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0277059 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0274939 |
| GPC6 | glypican 6 | 0.0264419 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0264365 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0262066 |
| EZR | ezrin | 0.0261275 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0260647 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0254507 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0253626 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0253497 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0247581 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0246355 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0246102 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.024536 |
| SGMS2 | sphingomyelin synthase 2 | 0.0241765 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0232992 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0222815 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0214439 |
| RPL37 | ribosomal protein L37 | 0.0213235 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0211404 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0211343 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0209324 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.0202121 |
| LYST | lysosomal trafficking regulator | 0.0202031 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0198965 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0198922 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0194347 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0192285 |
| GPATCH2L | G patch domain containing 2-like | 0.01901 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0190031 |
| RPL36 | ribosomal protein L36 | 0.0189649 |
| TAGLN2 | transgelin 2 | 0.0189377 |
| RASEF | RAS and EF-hand domain containing | 0.0187827 |
| RPL23 | ribosomal protein L23 | 0.0182102 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.018045 |
| RACK1 | receptor for activated C kinase 1 | 0.0180333 |
| EMP1 | epithelial membrane protein 1 | 0.0179595 |
| ABLIM1 | actin binding LIM protein 1 | 0.01789 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.017641 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0175655 |
| PCDH7 | protocadherin 7 | 0.0175358 |
| PLIN2 | perilipin 2 | 0.0175049 |
| CRY1 | cryptochrome circadian clock 1 | 0.0174874 |
| FOSL1 | FOS-like antigen 1 | 0.0174361 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0172439 |
| RPL37A | ribosomal protein L37a | 0.0171647 |
| VEGFA | vascular endothelial growth factor A | 0.0171065 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0168357 |
| RND3 | Rho family GTPase 3 | 0.0168255 |
| ITGAV | integrin, alpha V | 0.0167443 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0162608 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0161784 |
| IFI44L | interferon-induced protein 44-like | 0.0161303 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0160532 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0159786 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.015974 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0158478 |
| RPS12 | ribosomal protein S12 | 0.0157538 |
| NEBL | nebulette | 0.0157465 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0156749 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0154774 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0154773 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0149823 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0148425 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0146635 |
| IL6R | interleukin 6 receptor | 0.0145706 |
| CD109 | CD109 molecule | 0.0143755 |
| EGFR | epidermal growth factor receptor | 0.0142918 |
| CSPP1 | centrosome and spindle pole associated protein 1 | 0.0142544 |
| MYO1E | myosin IE | 0.0141641 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0141123 |
| RPL12 | ribosomal protein L12 | 0.0140845 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0140824 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0140737 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0140354 |
| IRS2 | insulin receptor substrate 2 | 0.0139221 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0137413 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.416392 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.325334 |
| FN1 | fibronectin 1 | -0.20142 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.183427 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.178048 |
| CANX | calnexin | -0.148724 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.143876 |
| NRG1 | neuregulin 1 | -0.130618 |
| PTMA | prothymosin, alpha | -0.10115 |
| SQSTM1 | sequestosome 1 | -0.100275 |
| GLIS3 | GLIS family zinc finger 3 | -0.0788278 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0767804 |
| ITGA1 | integrin, alpha 1 | -0.0698029 |
| HMGA2 | high mobility group AT-hook 2 | -0.069555 |
| NRP1 | neuropilin 1 | -0.0653348 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0589369 |
| TMEM156 | transmembrane protein 156 | -0.0576953 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.056562 |
| VCL | vinculin | -0.0540855 |
| SYT1 | synaptotagmin I | -0.0515302 |
| OGA | O-GlcNAcase | -0.0514631 |
| MKI67 | marker of proliferation Ki-67 | -0.0500681 |
| RBM39 | RNA binding motif protein 39 | -0.0491908 |
| H1-0 | H1.0 linker histone | -0.0483904 |
| SMOX | spermine oxidase | -0.0435839 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.041522 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0409462 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0406777 |
| OSMR | oncostatin M receptor | -0.0396814 |
| S100A6 | S100 calcium binding protein A6 | -0.0384783 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0382318 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0372614 |
| CENPF | centromere protein F, 350/400kDa | -0.0372371 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0365748 |
| FAM20C | family with sequence similarity 20, member C | -0.0365242 |
| VMP1 | vacuole membrane protein 1 | -0.0364741 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0362062 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0361991 |
| ACTG1 | actin gamma 1 | -0.0359517 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0356672 |
| PGK1 | phosphoglycerate kinase 1 | -0.0356586 |
| FNBP1 | formin binding protein 1 | -0.0354825 |
| TMSB10 | thymosin beta 10 | -0.0353334 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0353075 |
| PELO | pelota homolog (Drosophila) | -0.0352273 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0349694 |
| RUNX2 | runt-related transcription factor 2 | -0.0349373 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0344757 |
| TMSB4X | thymosin beta 4, X-linked | -0.0342982 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.034203 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0341148 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.033689 |
| WDR45B | WD repeat domain 45B | -0.0330202 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0329653 |
| HDLBP | high density lipoprotein binding protein | -0.0326737 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0324107 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0323514 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.032269 |
| CALU | calumenin | -0.0322153 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0319695 |
| HPCAL1 | hippocalcin-like 1 | -0.0316825 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0313302 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.031245 |
| KLHL5 | kelch-like family member 5 | -0.0311891 |
| ARF1 | ADP-ribosylation factor 1 | -0.0310641 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0307447 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0306472 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0304521 |
| ETV1 | ets variant 1 | -0.0303165 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0303107 |
| COPA | coatomer protein complex, subunit alpha | -0.030046 |
| GOLT1B | golgi transport 1B | -0.0298109 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0296777 |
| ACTN4 | actinin, alpha 4 | -0.0293831 |
| RAI14 | retinoic acid induced 14 | -0.0293101 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0291181 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0289739 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0288886 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0288507 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0284785 |
| RAD21 | RAD21 homolog (S. pombe) | -0.028406 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.028369 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0282927 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0280915 |
| TMEM263 | transmembrane protein 263 | -0.0280247 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0277369 |
| SUCO | SUN domain containing ossification factor | -0.0277251 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0275085 |
| IER3 | immediate early response 3 | -0.0273248 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0272799 |
| AHR | aryl hydrocarbon receptor | -0.0272561 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0272085 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0271814 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0270076 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0269518 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0267475 |
| MT2A | metallothionein 2A | -0.0267397 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0267195 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0266398 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.02662 |
