| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benztropine (mesylate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Benztropine (mesylate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.202967 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.170248 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.123367 |
| NAV1 | neuron navigator 1 | 0.106784 |
| AHNAK | AHNAK nucleoprotein | 0.101976 |
| PODXL | podocalyxin-like | 0.0973184 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0934364 |
| PLAT | plasminogen activator, tissue | 0.0932344 |
| VIM | vimentin | 0.0925746 |
| CD44 | CD44 molecule (Indian blood group) | 0.0882184 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0846253 |
| COL3A1 | collagen, type III, alpha 1 | 0.0781774 |
| FBN1 | fibrillin 1 | 0.0720778 |
| THBS2 | thrombospondin 2 | 0.0637998 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0559241 |
| LOX | lysyl oxidase | 0.0539368 |
| LOXL2 | lysyl oxidase-like 2 | 0.0538494 |
| MAP1B | microtubule-associated protein 1B | 0.0525976 |
| HLA-B | major histocompatibility complex, class I, B | 0.05171 |
| COL1A2 | collagen, type I, alpha 2 | 0.0503482 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0487121 |
| GLIS3 | GLIS family zinc finger 3 | 0.0486794 |
| B2M | beta-2-microglobulin | 0.046542 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0430673 |
| COL5A2 | collagen, type V, alpha 2 | 0.0422268 |
| MX2 | MX dynamin-like GTPase 2 | 0.0421801 |
| CD99 | CD99 molecule | 0.0392982 |
| COL5A1 | collagen, type V, alpha 1 | 0.0384296 |
| ANXA2 | annexin A2 | 0.0383297 |
| TMSB4X | thymosin beta 4, X-linked | 0.0370921 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0369744 |
| SEPTIN9 | septin 9 | 0.036763 |
| CANX | calnexin | 0.0354016 |
| CTSB | cathepsin B | 0.0352546 |
| EHBP1 | EH domain binding protein 1 | 0.0348812 |
| GPC6 | glypican 6 | 0.0346975 |
| HLA-C | major histocompatibility complex, class I, C | 0.033611 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0334679 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.033349 |
| APP | amyloid beta (A4) precursor protein | 0.0324101 |
| RNF213 | ring finger protein 213 | 0.0321621 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0319469 |
| SUCNR1 | succinate receptor 1 | 0.030346 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0292959 |
| HLA-A | major histocompatibility complex, class I, A | 0.0292195 |
| RAI14 | retinoic acid induced 14 | 0.0287487 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0285735 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0281728 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0274371 |
| SMYD3 | SET and MYND domain containing 3 | 0.0273694 |
| CUX1 | cut-like homeobox 1 | 0.0272137 |
| HLA-E | major histocompatibility complex, class I, E | 0.0270224 |
| MEIS2 | Meis homeobox 2 | 0.0258107 |
| PARD3 | par-3 family cell polarity regulator | 0.0255564 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.025448 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.025299 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0250269 |
| TPM3 | tropomyosin 3 | 0.0248854 |
| PRSS23 | protease, serine, 23 | 0.0248589 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0246742 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0244821 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.0244299 |
| ARRDC3 | arrestin domain containing 3 | 0.0243294 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0240685 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0240154 |
| FLNB | filamin B, beta | 0.0237549 |
| RUNX1 | runt-related transcription factor 1 | 0.0232698 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0232526 |
| GSE1 | Gse1 coiled-coil protein | 0.0229943 |
| SLC39A11 | solute carrier family 39, member 11 | 0.022555 |
| SBF2 | SET binding factor 2 | 0.0225315 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0224239 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0223576 |
| BPTF | bromodomain PHD finger transcription factor | 0.0222239 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0218284 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0215617 |
| EFNA5 | ephrin-A5 | 0.0215194 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0214608 |
| OGA | O-GlcNAcase | 0.0212703 |
| SLFN5 | schlafen family member 5 | 0.0211452 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0211329 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0210708 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.020947 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0207589 |
| STC1 | stanniocalcin 1 | 0.0203114 |
| ADAR | adenosine deaminase, RNA-specific | 0.020065 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0200292 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0198652 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0198483 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0198473 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0196965 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0196033 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0194797 |
| ATP13A3 | ATPase type 13A3 | 0.0194249 |
| ZNF148 | zinc finger protein 148 | 0.019421 |
| CAVIN1 | caveolae associated protein 1 | 0.0193722 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0191965 |
| VEGFA | vascular endothelial growth factor A | 0.0191875 |
| MAP4 | microtubule-associated protein 4 | 0.0188195 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0185483 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0598018 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0401009 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0383262 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0273541 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0265099 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0258418 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0244888 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0240645 |
| POTEF | POTE ankyrin domain family, member F | -0.0227397 |
| LDHA | lactate dehydrogenase A | -0.0213649 |
| ADM | adrenomedullin | -0.0202385 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0200342 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0190916 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0175137 |
| RND3 | Rho family GTPase 3 | -0.0174643 |
| MSI2 | musashi RNA-binding protein 2 | -0.0169958 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0166528 |
| PKM | pyruvate kinase, muscle | -0.0158847 |
| NDRG1 | N-myc downstream regulated 1 | -0.0157198 |
| FOSL1 | FOS-like antigen 1 | -0.0153614 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0153366 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0148519 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0147174 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0146335 |
| CTBP2 | C-terminal binding protein 2 | -0.0145733 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0145215 |
| CENPF | centromere protein F, 350/400kDa | -0.014296 |
| FTL | ferritin, light polypeptide | -0.0140828 |
| JUN | jun proto-oncogene | -0.0138691 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0128358 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0128152 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0126689 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0122962 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0122846 |
| INSIG1 | insulin induced gene 1 | -0.0122474 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0120878 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0118085 |
| OXSR1 | oxidative stress responsive 1 | -0.0115099 |
| INSIG2 | insulin induced gene 2 | -0.0113259 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0112521 |
| RYBP | RING1 and YY1 binding protein | -0.011187 |
| UBTD2 | ubiquitin domain containing 2 | -0.0110889 |
| HELZ | helicase with zinc finger | -0.0104002 |
| ZNF207 | zinc finger protein 207 | -0.0103281 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0102721 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.0102216 |
| SPNS2 | spinster homolog 2 (Drosophila) | -0.0101706 |
| RHEB | Ras homolog enriched in brain | -0.0100739 |
| NUP58 | nucleoporin 58 | -0.00974922 |
| RNF24 | ring finger protein 24 | -0.0097123 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00965137 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -0.00945762 |
| FNBP1L | formin binding protein 1-like | -0.0091324 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.00909541 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.00902218 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00899381 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.00882338 |
| HBP1 | HMG-box transcription factor 1 | -0.00880165 |
| TFG | TRK-fused gene | -0.00876224 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.00869226 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.00864536 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.00854389 |
| TUFT1 | tuftelin 1 | -0.0084722 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.00841801 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.00826704 |
| FOSL2 | FOS-like antigen 2 | -0.00822457 |
| SERTAD2 | SERTA domain containing 2 | -0.00812606 |
| LAMA5 | laminin, alpha 5 | -0.00796309 |
| RREB1 | ras responsive element binding protein 1 | -0.00793571 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00792925 |
| PER1 | period circadian clock 1 | -0.00786069 |
| PLK2 | polo-like kinase 2 | -0.00782939 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.00771622 |
| SEC24A | SEC24 family member A | -0.0077096 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00753429 |
| ANKRD30B | ankyrin repeat domain 30B | -0.0075147 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.00746407 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | -0.00746307 |
| ARF4 | ADP-ribosylation factor 4 | -0.00739443 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0073342 |
| ZFP36 | ZFP36 ring finger protein | -0.00732122 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.00728031 |
| FAM107B | family with sequence similarity 107, member B | -0.00727852 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.00726339 |
| CRY1 | cryptochrome circadian clock 1 | -0.0072354 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.00722683 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00721273 |
| SEC61G | Sec61 gamma subunit | -0.00715304 |
| CD109 | CD109 molecule | -0.00714187 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.00711439 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | -0.00710164 |
| COPA | coatomer protein complex, subunit alpha | -0.00704948 |
| USP3 | ubiquitin specific peptidase 3 | -0.00700167 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00697352 |
| RIOK3 | RIO kinase 3 | -0.00692577 |
| DTNA | dystrobrevin, alpha | -0.00691346 |
| LMNA | lamin A/C | -0.00682774 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.00681266 |
| TBC1D12 | TBC1 domain family, member 12 | -0.00680654 |
| RNASE3 | ribonuclease, RNase A family, 3 | -0.00677429 |
