| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benztropine (mesylate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benztropine (mesylate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.144704 |
| HLA-A | major histocompatibility complex, class I, A | 0.113702 |
| AHNAK | AHNAK nucleoprotein | 0.0860488 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0800439 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0742193 |
| MT2A | metallothionein 2A | 0.0736941 |
| ANXA2 | annexin A2 | 0.0683021 |
| TMSB4X | thymosin beta 4, X-linked | 0.0672497 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0666196 |
| LAMB3 | laminin, beta 3 | 0.0647129 |
| MT1X | metallothionein 1X | 0.0532792 |
| HLA-C | major histocompatibility complex, class I, C | 0.0516125 |
| ENO1 | enolase 1, (alpha) | 0.0493462 |
| RNF213 | ring finger protein 213 | 0.0458833 |
| SMAD3 | SMAD family member 3 | 0.0451865 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0444551 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0421439 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0415774 |
| RPS8 | ribosomal protein S8 | 0.0411297 |
| B2M | beta-2-microglobulin | 0.0402315 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0396814 |
| RAD51B | RAD51 paralog B | 0.0374534 |
| TGM2 | transglutaminase 2 | 0.0350103 |
| VEGFA | vascular endothelial growth factor A | 0.0347494 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0341879 |
| HLA-B | major histocompatibility complex, class I, B | 0.0316307 |
| HLA-E | major histocompatibility complex, class I, E | 0.0315857 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0310359 |
| H1-0 | H1.0 linker histone | 0.0307407 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0306833 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0305947 |
| RPL23 | ribosomal protein L23 | 0.0290732 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0290196 |
| MMP7 | matrix metallopeptidase 7 | 0.0283878 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0268064 |
| PTMA | prothymosin, alpha | 0.0267001 |
| RPS3 | ribosomal protein S3 | 0.0266992 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0264781 |
| RPL35A | ribosomal protein L35a | 0.0257923 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0250791 |
| RPL19 | ribosomal protein L19 | 0.025068 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0249268 |
| NRG3 | neuregulin 3 | 0.0248244 |
| KLF6 | Kruppel-like factor 6 | 0.0245928 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0244898 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0240699 |
| FAM13A | family with sequence similarity 13, member A | 0.0238385 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.023629 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0232754 |
| ARRDC3 | arrestin domain containing 3 | 0.0232344 |
| RPS27A | ribosomal protein S27a | 0.0231534 |
| KIAA1217 | KIAA1217 | 0.0230574 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0225787 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0223898 |
| RACK1 | receptor for activated C kinase 1 | 0.0222241 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0219783 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0216472 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0214405 |
| YBX1 | Y box binding protein 1 | 0.0213337 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0212079 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.02099 |
| PLAU | plasminogen activator, urokinase | 0.0208037 |
| ZNF292 | zinc finger protein 292 | 0.0205634 |
| ACTG1 | actin gamma 1 | 0.0205342 |
| RPL28 | ribosomal protein L28 | 0.020307 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0199148 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0198285 |
| FLNA | filamin A, alpha | 0.0195922 |
| MX1 | MX dynamin-like GTPase 1 | 0.0195884 |
| UBC | ubiquitin C | 0.0195667 |
| G0S2 | G0/G1 switch 2 | 0.0193429 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0192822 |
| USP3 | ubiquitin specific peptidase 3 | 0.019188 |
| MUC16 | mucin 16, cell surface associated | 0.0188309 |
| CALR | calreticulin | 0.0187937 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0187213 |
| MX2 | MX dynamin-like GTPase 2 | 0.0184644 |
| BCL2L1 | BCL2-like 1 | 0.0183757 |
| HPCAL1 | hippocalcin-like 1 | 0.0183323 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0183235 |
| F11R | F11 receptor | 0.01828 |
| APOL2 | apolipoprotein L, 2 | 0.0182372 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0181782 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0180429 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0178714 |
| DST | dystonin | 0.017826 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0177305 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0176598 |
| MUC4 | mucin 4, cell surface associated | 0.0176431 |
| CP | ceruloplasmin (ferroxidase) | 0.0175695 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0166982 |
| CLIC1 | chloride intracellular channel 1 | 0.016374 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0161784 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0159696 |
| RPL37A | ribosomal protein L37a | 0.0157195 |
| PCDH7 | protocadherin 7 | 0.0156489 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0154016 |
| CANX | calnexin | 0.0153854 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0153779 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0153175 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0502494 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0467921 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0346568 |
| LMO7 | LIM domain 7 | -0.0346539 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0295295 |
| NDRG1 | N-myc downstream regulated 1 | -0.0275255 |
| DTNA | dystrobrevin, alpha | -0.0272266 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0265686 |
| HMGA1 | high mobility group AT-hook 1 | -0.0263927 |
| LDHA | lactate dehydrogenase A | -0.0262458 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0255852 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0243889 |
| EZR | ezrin | -0.0242927 |
| FLNB | filamin B, beta | -0.0236827 |
| KRT19 | keratin 19, type I | -0.0229827 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0227846 |
| POTEF | POTE ankyrin domain family, member F | -0.022752 |
| PKM | pyruvate kinase, muscle | -0.0220178 |
| MCU | mitochondrial calcium uniporter | -0.0216912 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0216544 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0213915 |
| OPTN | optineurin | -0.0212268 |
| SEC24A | SEC24 family member A | -0.0209126 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0207076 |
| INSIG1 | insulin induced gene 1 | -0.019673 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0196208 |
| RCOR1 | REST corepressor 1 | -0.0193315 |
| PLS3 | plastin 3 | -0.0192359 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0189089 |
| RBM39 | RNA binding motif protein 39 | -0.0187862 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0186146 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0185398 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0181127 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0177795 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0177494 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0176062 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0166331 |
| CCNL1 | cyclin L1 | -0.0166129 |
| CLTC | clathrin, heavy chain (Hc) | -0.0165545 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0164407 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0163332 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0161088 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0160888 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0160471 |
| TMEM165 | transmembrane protein 165 | -0.0160223 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0158827 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.015699 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.015552 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0154164 |
| JMJD1C | jumonji domain containing 1C | -0.015401 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0152805 |
| GOLGB1 | golgin B1 | -0.015219 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0148709 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0145941 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0144983 |
| MYADM | myeloid-associated differentiation marker | -0.0143676 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0142412 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0139633 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0138541 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0137306 |
| CLIC4 | chloride intracellular channel 4 | -0.0137194 |
| FMNL2 | formin-like 2 | -0.0137119 |
| TAPBP | TAP binding protein (tapasin) | -0.01363 |
| DSTN | destrin (actin depolymerizing factor) | -0.01355 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0135281 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0134258 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0132569 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0131899 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0131761 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0131466 |
| DIAPH1 | diaphanous-related formin 1 | -0.0131339 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0130732 |
| PERP | PERP, TP53 apoptosis effector | -0.0129699 |
| MAP1B | microtubule-associated protein 1B | -0.0128248 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0127917 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0124726 |
| JUP | junction plakoglobin | -0.0124635 |
| ERBIN | erbb2 interacting protein | -0.0124379 |
| MORF4L2 | mortality factor 4 like 2 | -0.0124141 |
| FRYL | FRY-like | -0.0124015 |
| SCFD1 | sec1 family domain containing 1 | -0.0123991 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0123245 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0122911 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.0121549 |
| TPM4 | tropomyosin 4 | -0.0119747 |
| WASF2 | WAS protein family, member 2 | -0.0119151 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0118256 |
| INSIG2 | insulin induced gene 2 | -0.011805 |
| TP53BP2 | tumor protein p53 binding protein 2 | -0.0118044 |
| CEP350 | centrosomal protein 350kDa | -0.0117664 |
| PCBP2 | poly(rC) binding protein 2 | -0.0115711 |
| MYO6 | myosin VI | -0.0114543 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0113057 |
| CCNK | cyclin K | -0.0111805 |
| EGR1 | early growth response 1 | -0.0111226 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0109762 |
| USP53 | ubiquitin specific peptidase 53 | -0.0109369 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0108616 |
| TMF1 | TATA element modulatory factor 1 | -0.0108018 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0107066 |
