| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benztropine (mesylate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Benztropine (mesylate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.154282 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0482231 |
| LSAMP | limbic system-associated membrane protein | 0.0457878 |
| FMN1 | formin 1 | 0.0446996 |
| COL3A1 | collagen, type III, alpha 1 | 0.0437952 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0437545 |
| LPIN1 | lipin 1 | 0.0432728 |
| SYT1 | synaptotagmin I | 0.0419554 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0398204 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0384339 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0379048 |
| PLAT | plasminogen activator, tissue | 0.0371231 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0354151 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0292561 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0283557 |
| AHNAK | AHNAK nucleoprotein | 0.0280139 |
| DST | dystonin | 0.0275307 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0270319 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0267322 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0262887 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0261486 |
| COL1A1 | collagen, type I, alpha 1 | 0.0259649 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0259045 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0257948 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0256407 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0256389 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0239874 |
| LMNA | lamin A/C | 0.0239425 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0238872 |
| HELZ | helicase with zinc finger | 0.0232291 |
| FNBP1 | formin binding protein 1 | 0.0229981 |
| ACTG1 | actin gamma 1 | 0.0226922 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0224838 |
| MAP1B | microtubule-associated protein 1B | 0.022365 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0222157 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0221969 |
| SPAG9 | sperm associated antigen 9 | 0.0221324 |
| FRMD4A | FERM domain containing 4A | 0.0219659 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0216587 |
| AHR | aryl hydrocarbon receptor | 0.0215116 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0214595 |
| OGA | O-GlcNAcase | 0.0213057 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0212487 |
| CALU | calumenin | 0.0211086 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0210811 |
| VEGFA | vascular endothelial growth factor A | 0.0208154 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0207666 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0207202 |
| SEPTIN9 | septin 9 | 0.020358 |
| ZNF292 | zinc finger protein 292 | 0.0202234 |
| CADM2 | cell adhesion molecule 2 | 0.0197498 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0190661 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0190636 |
| YEATS2 | YEATS domain containing 2 | 0.0188536 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0187705 |
| PCNX1 | pecanex 1 | 0.018403 |
| CASC3 | cancer susceptibility candidate 3 | 0.0182372 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.018059 |
| ENO1 | enolase 1, (alpha) | 0.0180077 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0178299 |
| SMAD3 | SMAD family member 3 | 0.0178274 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.017813 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0177108 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0174524 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0174072 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0170161 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0169517 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0168702 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0167058 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.016646 |
| AMOTL1 | angiomotin like 1 | 0.0166447 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0165937 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0165117 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0164824 |
| AOPEP | aminopeptidase O (putative) | 0.0164822 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0164708 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0163696 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0161649 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0161514 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0161465 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.015968 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0159404 |
| STC1 | stanniocalcin 1 | 0.0157938 |
| GPC5 | glypican 5 | 0.0157758 |
| XPO1 | exportin 1 | 0.0155069 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0154496 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0154163 |
| SIK3 | SIK family kinase 3 | 0.0153288 |
| APP | amyloid beta (A4) precursor protein | 0.015292 |
| FAM13A | family with sequence similarity 13, member A | 0.0152045 |
| RNF213 | ring finger protein 213 | 0.014989 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0149548 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0149531 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0148223 |
| GOLGA4 | golgin A4 | 0.0147371 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0147003 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0146599 |
| TLE4 | transducin-like enhancer of split 4 | 0.0143172 |
| KIF5B | kinesin family member 5B | 0.0142731 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0141864 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.247572 |
| VIM | vimentin | -0.0501617 |
| RPS6 | ribosomal protein S6 | -0.0434509 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0336605 |
| TMSB10 | thymosin beta 10 | -0.0307731 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0287229 |
| ASPH | aspartate beta-hydroxylase | -0.026022 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0256669 |
| RPL23 | ribosomal protein L23 | -0.0237522 |
| RPLP1 | ribosomal protein, large, P1 | -0.0216277 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0211967 |
| SCG2 | secretogranin II | -0.0209882 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0189874 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0184939 |
| RPL31 | ribosomal protein L31 | -0.018262 |
| RPS24 | ribosomal protein S24 | -0.018056 |
| FTL | ferritin, light polypeptide | -0.0173379 |
| GNAS | GNAS complex locus | -0.017328 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0171193 |
| PCBP2 | poly(rC) binding protein 2 | -0.0164706 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0154472 |
| DSTN | destrin (actin depolymerizing factor) | -0.0152512 |
| RPS19 | ribosomal protein S19 | -0.015175 |
| NDRG1 | N-myc downstream regulated 1 | -0.0143022 |
| ITGAV | integrin, alpha V | -0.014212 |
| JMJD1C | jumonji domain containing 1C | -0.0140921 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0133487 |
| RPL32 | ribosomal protein L32 | -0.0131368 |
| RPS16 | ribosomal protein S16 | -0.0129076 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0127981 |
| DACH2 | dachshund family transcription factor 2 | -0.0127927 |
| RPL34 | ribosomal protein L34 | -0.0124472 |
| RBM39 | RNA binding motif protein 39 | -0.0122497 |
| RPS14 | ribosomal protein S14 | -0.0122269 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | -0.0119205 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0118777 |
| DPH6 | diphthamine biosynthesis 6 | -0.0118402 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0118173 |
| RPS17 | ribosomal protein S17 | -0.0117946 |
| RBM25 | RNA binding motif protein 25 | -0.0117558 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.011725 |
| RRBP1 | ribosome binding protein 1 | -0.0115744 |
| FHIT | fragile histidine triad | -0.0113063 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0113004 |
| RPS23 | ribosomal protein S23 | -0.0111992 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0111313 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0110933 |
| PFN1 | profilin 1 | -0.0107956 |
| RBM26 | RNA binding motif protein 26 | -0.0106664 |
| RPL35A | ribosomal protein L35a | -0.010417 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0102918 |
| RPL12 | ribosomal protein L12 | -0.0101908 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0101831 |
| POTEF | POTE ankyrin domain family, member F | -0.0101385 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0100071 |
| SERF2 | small EDRK-rich factor 2 | -0.00990657 |
| THOC1 | THO complex 1 | -0.00987726 |
| EGR1 | early growth response 1 | -0.00982787 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.00979867 |
| PDE8A | phosphodiesterase 8A | -0.0097664 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.00971234 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.00969265 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.00957948 |
| RPL35 | ribosomal protein L35 | -0.00940264 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.00930164 |
| NEBL | nebulette | -0.00919775 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00914653 |
| TENM3 | teneurin transmembrane protein 3 | -0.0091052 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00909272 |
| RGS2 | regulator of G-protein signaling 2 | -0.00906528 |
| RIC1 | RAB6A GEF complex partner 1 | -0.00905411 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.00904683 |
| CCND1 | cyclin D1 | -0.00894666 |
| RGS4 | regulator of G-protein signaling 4 | -0.0089211 |
| TPM4 | tropomyosin 4 | -0.0088682 |
| RAB5A | RAB5A, member RAS oncogene family | -0.00881344 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -0.00880205 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00879818 |
| ZNF609 | zinc finger protein 609 | -0.00875886 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.00869094 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00865317 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.00861664 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0085134 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.00844064 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00843554 |
| FRMD5 | FERM domain containing 5 | -0.00837006 |
| FBL | fibrillarin | -0.0083461 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.00833226 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.00832401 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.00830306 |
| MX1 | MX dynamin-like GTPase 1 | -0.0082237 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.00822154 |
| CPSF2 | cleavage and polyadenylation specific factor 2, 100kDa | -0.0081729 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.00816972 |
| CRH | corticotropin releasing hormone | -0.00813192 |
| SNX14 | sorting nexin 14 | -0.00809691 |
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 | -0.00804671 |
| HMGA1 | high mobility group AT-hook 1 | -0.00802245 |
| GSPT1 | G1 to S phase transition 1 | -0.00801689 |
| CDH13 | cadherin 13 | -0.00799454 |
