| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benztropine (mesylate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Benztropine (mesylate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.063233 |
| AHNAK | AHNAK nucleoprotein | 0.0526145 |
| RUNX1 | runt-related transcription factor 1 | 0.051796 |
| CANX | calnexin | 0.0485353 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0474571 |
| LCN2 | lipocalin 2 | 0.0472917 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0466529 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0442798 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0418037 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0413965 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0403916 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0403241 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0402515 |
| FAT1 | FAT atypical cadherin 1 | 0.0384533 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0383645 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0379001 |
| STK24 | serine/threonine kinase 24 | 0.0371892 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0360754 |
| ASPH | aspartate beta-hydroxylase | 0.0357478 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0353157 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0352525 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0345863 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0342925 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0339136 |
| TUFT1 | tuftelin 1 | 0.0330504 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.032301 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.031847 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0316934 |
| ATXN1 | ataxin 1 | 0.0316309 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.03097 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0303161 |
| PHF3 | PHD finger protein 3 | 0.0300438 |
| LYZ | lysozyme | 0.029976 |
| RAD51B | RAD51 paralog B | 0.0299287 |
| SBF2 | SET binding factor 2 | 0.0298701 |
| F11R | F11 receptor | 0.0298145 |
| ZNF292 | zinc finger protein 292 | 0.0297763 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0284166 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0277747 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0277557 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0276419 |
| RNF213 | ring finger protein 213 | 0.0275067 |
| MYO1E | myosin IE | 0.0275005 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0273533 |
| SMAD3 | SMAD family member 3 | 0.0273394 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0271723 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.026162 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0258545 |
| PGK1 | phosphoglycerate kinase 1 | 0.0256919 |
| ITGA6 | integrin, alpha 6 | 0.0254463 |
| MSI2 | musashi RNA-binding protein 2 | 0.0254374 |
| VCL | vinculin | 0.025365 |
| TRIM2 | tripartite motif containing 2 | 0.0246084 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0245929 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0245799 |
| VEGFA | vascular endothelial growth factor A | 0.0243886 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0242559 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0241575 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0238969 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0238885 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0237694 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0237457 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0236267 |
| NF1 | neurofibromin 1 | 0.0234863 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0234428 |
| EPCAM | epithelial cell adhesion molecule | 0.0233492 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0231973 |
| SMYD3 | SET and MYND domain containing 3 | 0.0228855 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0227516 |
| MUC13 | mucin 13, cell surface associated | 0.0227165 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0226936 |
| HLA-B | major histocompatibility complex, class I, B | 0.0223741 |
| DSPP | dentin sialophosphoprotein | 0.0223002 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0221289 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0220868 |
| BPTF | bromodomain PHD finger transcription factor | 0.0220839 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0219683 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0219581 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0214585 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0213741 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0213429 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0212717 |
| ACTN4 | actinin, alpha 4 | 0.021238 |
| SERINC5 | serine incorporator 5 | 0.0209392 |
| SDC4 | syndecan 4 | 0.0208358 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0206987 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0206645 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0205786 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0205311 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0204702 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0204078 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0203873 |
| OGA | O-GlcNAcase | 0.0203483 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0203294 |
| FHIT | fragile histidine triad | 0.0201879 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0201372 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0200644 |
| AOPEP | aminopeptidase O (putative) | 0.0200127 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0199827 |
| HLA-C | major histocompatibility complex, class I, C | 0.0199488 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.0723308 |
| EGR1 | early growth response 1 | -0.053602 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0384818 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0311586 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0221659 |
| PERP | PERP, TP53 apoptosis effector | -0.0208599 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0198277 |
| INTS6 | integrator complex subunit 6 | -0.019779 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0183547 |
| MORF4L2 | mortality factor 4 like 2 | -0.0182741 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0172902 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0172723 |
| IRF1 | interferon regulatory factor 1 | -0.0168103 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0158156 |
| ARF4 | ADP-ribosylation factor 4 | -0.0155618 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.014621 |
| WDR45B | WD repeat domain 45B | -0.0138766 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0136615 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0133275 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0132724 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0131619 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0127663 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0126115 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0124514 |
| CDHR2 | cadherin-related family member 2 | -0.0122526 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0119389 |
| S100A6 | S100 calcium binding protein A6 | -0.0116383 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0115247 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | -0.0115118 |
| DIAPH1 | diaphanous-related formin 1 | -0.0112101 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0108147 |
| TMSB10 | thymosin beta 10 | -0.0107641 |
| MT2A | metallothionein 2A | -0.0106151 |
| CST3 | cystatin C | -0.0105097 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0102115 |
| SEC24A | SEC24 family member A | -0.00997329 |
| ZNF432 | zinc finger protein 432 | -0.00983176 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.00956944 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00953747 |
| UFM1 | ubiquitin-fold modifier 1 | -0.00938574 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.00928929 |
| USP8 | ubiquitin specific peptidase 8 | -0.00918897 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.00914932 |
| TAPBP | TAP binding protein (tapasin) | -0.00912366 |
| GOLGB1 | golgin B1 | -0.00901459 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.00899356 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.00895933 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.00893043 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00892102 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0089206 |
| PMP22 | peripheral myelin protein 22 | -0.00878594 |
| KRT19 | keratin 19, type I | -0.00878271 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.00877315 |
| TAGLN2 | transgelin 2 | -0.00875681 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.00874327 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | -0.00872926 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00866879 |
| SDCBP | syndecan binding protein (syntenin) | -0.00855187 |
| MT1X | metallothionein 1X | -0.00848961 |
| TEX9 | testis expressed 9 | -0.00848274 |
| POF1B | premature ovarian failure, 1B | -0.00839575 |
| ANXA1 | annexin A1 | -0.00837165 |
| LGMN | legumain | -0.00836243 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | -0.00827909 |
| SYT1 | synaptotagmin I | -0.00824465 |
| EFHD2 | EF-hand domain family, member D2 | -0.00821399 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00820802 |
| CD68 | CD68 molecule | -0.00818778 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.00806391 |
| FNIP2 | folliculin interacting protein 2 | -0.00798194 |
| TXNDC11 | thioredoxin domain containing 11 | -0.00797014 |
| GK | glycerol kinase | -0.00796716 |
| NUCB2 | nucleobindin 2 | -0.00792931 |
| METTL16 | methyltransferase like 16 | -0.00790489 |
| ARLN | allregulin | -0.00789743 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | -0.00787047 |
| OPTN | optineurin | -0.00782675 |
| RRM2 | ribonucleotide reductase M2 | -0.00781259 |
| FAM111B | family with sequence similarity 111, member B | -0.00776397 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.00768609 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0076632 |
| MSMO1 | methylsterol monooxygenase 1 | -0.00765309 |
| XBP1 | X-box binding protein 1 | -0.00763605 |
| ZFP36 | ZFP36 ring finger protein | -0.00760119 |
| DST | dystonin | -0.00754232 |
| FTL | ferritin, light polypeptide | -0.00740198 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.00740025 |
| PML | promyelocytic leukemia | -0.00735842 |
| CREG2 | cellular repressor of E1A-stimulated genes 2 | -0.00732483 |
| ADIPOR2 | adiponectin receptor 2 | -0.00732129 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.00729818 |
| RPL27A | ribosomal protein L27a | -0.00727615 |
| SYT7 | synaptotagmin VII | -0.00725441 |
| NABP1 | nucleic acid binding protein 1 | -0.00723798 |
| RPL35 | ribosomal protein L35 | -0.00717386 |
| FBXO11 | F-box protein 11 | -0.00716366 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00703951 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.006995 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.00698869 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | -0.00698546 |
