| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benztropine (mesylate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Benztropine (mesylate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.128154 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0806195 |
| OGA | O-GlcNAcase | 0.0774812 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0740538 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0672284 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0614677 |
| CANX | calnexin | 0.060312 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0574933 |
| CALR | calreticulin | 0.0502383 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0498734 |
| SBF2 | SET binding factor 2 | 0.0493405 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0480461 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.047687 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0466826 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.044657 |
| AHNAK | AHNAK nucleoprotein | 0.0442056 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0433652 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0427495 |
| GOLGA4 | golgin A4 | 0.0421911 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0407812 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0407403 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0399786 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0395037 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0359918 |
| USP3 | ubiquitin specific peptidase 3 | 0.035686 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0351636 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0350914 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0346929 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0345472 |
| RLF | rearranged L-myc fusion | 0.0342373 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0335789 |
| RBM39 | RNA binding motif protein 39 | 0.0329864 |
| JMJD1C | jumonji domain containing 1C | 0.0328881 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0328228 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0320079 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0316751 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.031641 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.031544 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0308653 |
| TXNRD1 | thioredoxin reductase 1 | 0.0299595 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0294808 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0291292 |
| CALU | calumenin | 0.0290231 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0288556 |
| ZNF292 | zinc finger protein 292 | 0.0286634 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0286632 |
| NF1 | neurofibromin 1 | 0.0285937 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0285562 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0278116 |
| ZFR | zinc finger RNA binding protein | 0.0275407 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0274792 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0273699 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0272399 |
| COG5 | component of oligomeric golgi complex 5 | 0.0270277 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0270193 |
| HYOU1 | hypoxia up-regulated 1 | 0.0270175 |
| HELZ | helicase with zinc finger | 0.0268223 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0267041 |
| NUP58 | nucleoporin 58 | 0.026593 |
| THOC2 | THO complex 2 | 0.02625 |
| RPS3 | ribosomal protein S3 | 0.026136 |
| FAM13A | family with sequence similarity 13, member A | 0.025966 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0258762 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0257906 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0257431 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0256001 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0253265 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.025086 |
| VIM | vimentin | 0.0249983 |
| FN1 | fibronectin 1 | 0.0247451 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0246016 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0245837 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0243811 |
| RHEB | Ras homolog enriched in brain | 0.0243613 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0242946 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0239521 |
| XPO1 | exportin 1 | 0.0239483 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0239281 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0238708 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0238544 |
| WAC | WW domain containing adaptor with coiled-coil | 0.023727 |
| CDK8 | cyclin-dependent kinase 8 | 0.0236635 |
| MATR3 | matrin 3 | 0.0235784 |
| NCKAP1 | NCK-associated protein 1 | 0.0234747 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0234596 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0234229 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.0234213 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0233542 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0232841 |
| CCNC | cyclin C | 0.0232804 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.023272 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0230542 |
| FBXO42 | F-box protein 42 | 0.0230499 |
| AFTPH | aftiphilin | 0.023017 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0229727 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0228625 |
| STK24 | serine/threonine kinase 24 | 0.022756 |
| RPS27A | ribosomal protein S27a | 0.0227087 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0227043 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0226932 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.156106 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.120015 |
| KRT20 | keratin 20, type I | -0.117617 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.104026 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0922877 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0920143 |
| FRY | furry homolog (Drosophila) | -0.0884589 |
| LAMA4 | laminin, alpha 4 | -0.0814761 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0806223 |
| TJP1 | tight junction protein 1 | -0.0805419 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0727774 |
| SMAD3 | SMAD family member 3 | -0.0706739 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0676746 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0648356 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0623865 |
| EGR1 | early growth response 1 | -0.060813 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0567813 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0527987 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0527209 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0524838 |
| LDHA | lactate dehydrogenase A | -0.0518237 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0515591 |
| LYZ | lysozyme | -0.0502017 |
| POTEF | POTE ankyrin domain family, member F | -0.0491292 |
| MMP7 | matrix metallopeptidase 7 | -0.0479976 |
| FNDC3B | fibronectin type III domain containing 3B | -0.04786 |
| KRT19 | keratin 19, type I | -0.0435632 |
| POF1B | premature ovarian failure, 1B | -0.0424169 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0413231 |
| PRR5L | proline rich 5 like | -0.0404396 |
| TMEM123 | transmembrane protein 123 | -0.0402985 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0396983 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0391192 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0384019 |
| S100A10 | S100 calcium binding protein A10 | -0.037656 |
| TRIB1 | tribbles pseudokinase 1 | -0.037354 |
| TMEM65 | transmembrane protein 65 | -0.0362226 |
| NDRG1 | N-myc downstream regulated 1 | -0.0361975 |
| ETV6 | ets variant 6 | -0.0359086 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0354527 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0340266 |
| ANXA2 | annexin A2 | -0.0338814 |
| MYO5B | myosin VB | -0.033825 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.033781 |
| ASPH | aspartate beta-hydroxylase | -0.032706 |
| DIAPH2 | diaphanous-related formin 2 | -0.0324989 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0318666 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0311132 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0309712 |
| TMSB10 | thymosin beta 10 | -0.0309656 |
| PGK1 | phosphoglycerate kinase 1 | -0.0309258 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0305725 |
| SGMS2 | sphingomyelin synthase 2 | -0.0300456 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.0299054 |
| CTBP2 | C-terminal binding protein 2 | -0.0298399 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0295603 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0289839 |
| PKM | pyruvate kinase, muscle | -0.0288566 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0287723 |
| NTN4 | netrin 4 | -0.0287664 |
| FAT1 | FAT atypical cadherin 1 | -0.0286791 |
| RASEF | RAS and EF-hand domain containing | -0.0285466 |
| PCED1B | PC-esterase domain containing 1B | -0.0283525 |
| RNF213 | ring finger protein 213 | -0.0282294 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0280398 |
| PLK2 | polo-like kinase 2 | -0.0272815 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0271502 |
| JUN | jun proto-oncogene | -0.0263646 |
| DST | dystonin | -0.0259887 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.025839 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0257735 |
| EMP1 | epithelial membrane protein 1 | -0.0256106 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0255594 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.025514 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0253411 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | -0.0251135 |
| KRT18 | keratin 18, type I | -0.0246668 |
| CAPN8 | calpain 8 | -0.0244669 |
| LIMA1 | LIM domain and actin binding 1 | -0.0238495 |
| PDLIM5 | PDZ and LIM domain 5 | -0.023828 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0235224 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0234132 |
| S100A6 | S100 calcium binding protein A6 | -0.0232883 |
| MCU | mitochondrial calcium uniporter | -0.0232333 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.022994 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0226193 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0226093 |
| CA12 | carbonic anhydrase XII | -0.0225067 |
| EXT1 | exostosin glycosyltransferase 1 | -0.022342 |
| ABHD2 | abhydrolase domain containing 2 | -0.0223299 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0222227 |
| INTS6 | integrator complex subunit 6 | -0.0222012 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0220842 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0219065 |
| MECOM | MDS1 and EVI1 complex locus | -0.0216927 |
| GSN | gelsolin | -0.0213755 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0212249 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0209464 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.020762 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0206529 |
