| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benztropine (mesylate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Benztropine (mesylate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0829438 |
| SMAD3 | SMAD family member 3 | 0.0803479 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0771359 |
| ANXA2 | annexin A2 | 0.07212 |
| ZFP36 | ZFP36 ring finger protein | 0.0648255 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0622518 |
| ARRDC3 | arrestin domain containing 3 | 0.0597025 |
| TXNRD1 | thioredoxin reductase 1 | 0.0587615 |
| CD44 | CD44 molecule (Indian blood group) | 0.0562587 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0549867 |
| TMEM41B | transmembrane protein 41B | 0.0535054 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0520012 |
| ACTN4 | actinin, alpha 4 | 0.0503478 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0495163 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0492666 |
| OGA | O-GlcNAcase | 0.0460472 |
| ZNF292 | zinc finger protein 292 | 0.0456056 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0453161 |
| JMJD1C | jumonji domain containing 1C | 0.0442161 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.041404 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0413584 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0412959 |
| FOSL1 | FOS-like antigen 1 | 0.0410754 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0382703 |
| SPAG9 | sperm associated antigen 9 | 0.037084 |
| RTN4 | reticulon 4 | 0.036912 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0344113 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0340423 |
| B2M | beta-2-microglobulin | 0.0335329 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0327927 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0321891 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0312168 |
| SFTPA2 | surfactant protein A2 | 0.0309367 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0297855 |
| ANLN | anillin, actin binding protein | 0.0294663 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.029071 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0289934 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0288438 |
| VMP1 | vacuole membrane protein 1 | 0.0281371 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0277793 |
| CCNL1 | cyclin L1 | 0.0276504 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0275775 |
| YBX1 | Y box binding protein 1 | 0.0275014 |
| KLF6 | Kruppel-like factor 6 | 0.027401 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0273883 |
| MATR3 | matrin 3 | 0.0269222 |
| CDK19 | cyclin-dependent kinase 19 | 0.0269116 |
| SNX14 | sorting nexin 14 | 0.0266903 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0263742 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0263464 |
| RPS3 | ribosomal protein S3 | 0.0263084 |
| MED13L | mediator complex subunit 13-like | 0.0262308 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0262133 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0257358 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.025463 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0254627 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0250525 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0247154 |
| ENO1 | enolase 1, (alpha) | 0.0244146 |
| ATP13A3 | ATPase type 13A3 | 0.024407 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0243965 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0241241 |
| TPD52 | tumor protein D52 | 0.0235915 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0235107 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0234749 |
| XPO1 | exportin 1 | 0.0232762 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0231433 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.022859 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0228187 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0228174 |
| SQSTM1 | sequestosome 1 | 0.0228131 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0227818 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0227452 |
| AFAP1 | actin filament associated protein 1 | 0.0222084 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0218914 |
| ANGPTL4 | angiopoietin-like 4 | 0.0215486 |
| USP3 | ubiquitin specific peptidase 3 | 0.0211326 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0211269 |
| SBF2 | SET binding factor 2 | 0.0210247 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0208046 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | 0.0206718 |
| SEPTIN9 | septin 9 | 0.0205014 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.020168 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0200708 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0198207 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0198032 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0195633 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0191641 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0191165 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0190731 |
| FOXO3 | forkhead box O3 | 0.0190601 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0189032 |
| SUCO | SUN domain containing ossification factor | 0.0185646 |
| PHIP | pleckstrin homology domain interacting protein | 0.0185371 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0185276 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0185198 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0185174 |
| NOP58 | NOP58 ribonucleoprotein | 0.0183487 |
| AFDN | afadin, adherens junction formation factor | 0.0182862 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0182119 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.194351 |
| VIM | vimentin | -0.105888 |
| VCL | vinculin | -0.0896273 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0867849 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0773753 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0714109 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0651893 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0559322 |
| HMGA2 | high mobility group AT-hook 2 | -0.0497946 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0494868 |
| TMSB10 | thymosin beta 10 | -0.0480751 |
| DST | dystonin | -0.039966 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0392382 |
| INTS6 | integrator complex subunit 6 | -0.0380176 |
| AHNAK | AHNAK nucleoprotein | -0.0379097 |
| LDHA | lactate dehydrogenase A | -0.0347638 |
| EGFR | epidermal growth factor receptor | -0.0341595 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0338713 |
| RPS24 | ribosomal protein S24 | -0.0314183 |
| MYO1E | myosin IE | -0.0299448 |
| RNF220 | ring finger protein 220 | -0.02986 |
| EGR1 | early growth response 1 | -0.0297477 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0295823 |
| EHBP1 | EH domain binding protein 1 | -0.0280023 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0272444 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0271883 |
| NAV2 | neuron navigator 2 | -0.0269441 |
| ATG7 | autophagy related 7 | -0.0265827 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0265026 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0264472 |
| HMGA1 | high mobility group AT-hook 1 | -0.0244127 |
| CTSD | cathepsin D | -0.024317 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0241701 |
| TNS3 | tensin 3 | -0.0241291 |
| DIAPH2 | diaphanous-related formin 2 | -0.0231874 |
| PTMA | prothymosin, alpha | -0.023176 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.022405 |
| PTK2 | protein tyrosine kinase 2 | -0.0217033 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0215192 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0213379 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0197521 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0195797 |
| KRT18 | keratin 18, type I | -0.0191351 |
| RSU1 | Ras suppressor protein 1 | -0.0181249 |
| KRT8 | keratin 8, type II | -0.0181019 |
| NHSL1 | NHS-like 1 | -0.0180296 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0177331 |
| RASAL2 | RAS protein activator like 2 | -0.0174401 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.017218 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.017206 |
| ZNF407 | zinc finger protein 407 | -0.0171421 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0171286 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0162221 |
| NEK10 | NIMA-related kinase 10 | -0.0161204 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0160836 |
| EXOC4 | exocyst complex component 4 | -0.0154609 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0152409 |
| MYO10 | myosin X | -0.0152369 |
| RPLP1 | ribosomal protein, large, P1 | -0.0150428 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0146766 |
| HDAC9 | histone deacetylase 9 | -0.0145832 |
| FBL | fibrillarin | -0.0144842 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0144374 |
| TPM1 | tropomyosin 1 (alpha) | -0.01443 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0144008 |
| ATM | ATM serine/threonine kinase | -0.0143519 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0143417 |
| RPL4 | ribosomal protein L4 | -0.0143325 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.01424 |
| CDV3 | CDV3 homolog (mouse) | -0.0140976 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0137855 |
| MCL1 | myeloid cell leukemia 1 | -0.0136369 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -0.0135278 |
| CTBP2 | C-terminal binding protein 2 | -0.0133424 |
| RPS16 | ribosomal protein S16 | -0.0132886 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0130518 |
| SETX | senataxin | -0.0130367 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0128906 |
| CUX1 | cut-like homeobox 1 | -0.0127281 |
| COMMD10 | COMM domain containing 10 | -0.0126405 |
| RAD51B | RAD51 paralog B | -0.0126027 |
| MAP1B | microtubule-associated protein 1B | -0.0125263 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.012517 |
| CMIP | c-Maf inducing protein | -0.0122717 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | -0.0122066 |
| PKM | pyruvate kinase, muscle | -0.0121977 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0121952 |
| PLIN2 | perilipin 2 | -0.0121058 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0120177 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0118894 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0117841 |
| SP100 | SP100 nuclear antigen | -0.0117612 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0117367 |
| GOLGB1 | golgin B1 | -0.0116821 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0115966 |
| RIGI | RNA sensor RIG-I | -0.0115413 |
| RPL9 | ribosomal protein L9 | -0.0113961 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0113653 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0113208 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0111383 |
