| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benztropine (mesylate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benztropine (mesylate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.199819 |
| MUC4 | mucin 4, cell surface associated | 0.0836902 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0812045 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0798374 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0746918 |
| C3 | complement component 3 | 0.0702571 |
| VEGFA | vascular endothelial growth factor A | 0.0668425 |
| MUC16 | mucin 16, cell surface associated | 0.0653928 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0615727 |
| AHNAK | AHNAK nucleoprotein | 0.0569258 |
| HLA-A | major histocompatibility complex, class I, A | 0.054876 |
| B2M | beta-2-microglobulin | 0.054828 |
| SMAD3 | SMAD family member 3 | 0.0527934 |
| TMSB4X | thymosin beta 4, X-linked | 0.05087 |
| RNF213 | ring finger protein 213 | 0.0485967 |
| EGR1 | early growth response 1 | 0.0479045 |
| ETV6 | ets variant 6 | 0.0476023 |
| HLA-B | major histocompatibility complex, class I, B | 0.0474302 |
| TGM2 | transglutaminase 2 | 0.0467085 |
| KRT17 | keratin 17, type I | 0.0445657 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0429426 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0423006 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0417439 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0414922 |
| SEPTIN9 | septin 9 | 0.0405482 |
| CALR | calreticulin | 0.0382517 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0379472 |
| THBS1 | thrombospondin 1 | 0.0377736 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0372415 |
| BRD4 | bromodomain containing 4 | 0.0370044 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0369265 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.036164 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0361086 |
| ENO1 | enolase 1, (alpha) | 0.0355975 |
| NDRG1 | N-myc downstream regulated 1 | 0.0353121 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0349022 |
| DSPP | dentin sialophosphoprotein | 0.0341208 |
| ARRDC3 | arrestin domain containing 3 | 0.0338618 |
| DUSP5 | dual specificity phosphatase 5 | 0.0328364 |
| HLA-E | major histocompatibility complex, class I, E | 0.0324611 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0315471 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.031211 |
| XPO1 | exportin 1 | 0.0308879 |
| EMP1 | epithelial membrane protein 1 | 0.030867 |
| EZR | ezrin | 0.0307146 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0300195 |
| YBX3 | Y box binding protein 3 | 0.02963 |
| RPS3 | ribosomal protein S3 | 0.0290203 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0287091 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0285142 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0283289 |
| IRS2 | insulin receptor substrate 2 | 0.0277992 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0277609 |
| VMP1 | vacuole membrane protein 1 | 0.0275479 |
| BPTF | bromodomain PHD finger transcription factor | 0.0270369 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0270316 |
| BRD2 | bromodomain containing 2 | 0.0269014 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0268771 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0268707 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0267946 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0266887 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0265442 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0261065 |
| TXNIP | thioredoxin interacting protein | 0.0260077 |
| ANXA2 | annexin A2 | 0.0258837 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0257615 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0257057 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0257037 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0253087 |
| CCNL1 | cyclin L1 | 0.0247183 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.024539 |
| DPYD | dihydropyrimidine dehydrogenase | 0.024271 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.024262 |
| PLAT | plasminogen activator, tissue | 0.0241559 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0231566 |
| RAD51B | RAD51 paralog B | 0.0231146 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0227982 |
| TPM3 | tropomyosin 3 | 0.0224492 |
| FAM3C | family with sequence similarity 3, member C | 0.0224416 |
| ERBIN | erbb2 interacting protein | 0.0222565 |
| RPN1 | ribophorin I | 0.0218998 |
| LIPH | lipase, member H | 0.021873 |
| ATXN1 | ataxin 1 | 0.021495 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0213943 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0213861 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0213698 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0212579 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0211423 |
| HDAC8 | histone deacetylase 8 | 0.0210165 |
| HLA-C | major histocompatibility complex, class I, C | 0.0205499 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0205259 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0200971 |
| KRT7 | keratin 7, type II | 0.0200006 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0199802 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0199392 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0198027 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0196051 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0195806 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0192592 |
| MX1 | MX dynamin-like GTPase 1 | 0.0192299 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA1 | high mobility group AT-hook 1 | -0.0958187 |
| LMO7 | LIM domain 7 | -0.0951852 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0921546 |
| TMSB10 | thymosin beta 10 | -0.0909214 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0768388 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0757042 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.069176 |
| PTMA | prothymosin, alpha | -0.060409 |
| RPS6 | ribosomal protein S6 | -0.0592237 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0531408 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0517867 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0493329 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0481413 |
| RPL23 | ribosomal protein L23 | -0.0472014 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0453329 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0452159 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.041121 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0409312 |
| RPS24 | ribosomal protein S24 | -0.0405342 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0400116 |
| S100A6 | S100 calcium binding protein A6 | -0.0376497 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0363035 |
| RBM39 | RNA binding motif protein 39 | -0.0362847 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0353233 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0346011 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0345694 |
| PDE8A | phosphodiesterase 8A | -0.0339229 |
| RPLP1 | ribosomal protein, large, P1 | -0.0336225 |
| ASPH | aspartate beta-hydroxylase | -0.0334674 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0311995 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0301622 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.029625 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0292568 |
| FRMD5 | FERM domain containing 5 | -0.0291257 |
| RPL34 | ribosomal protein L34 | -0.0284984 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0284762 |
| MEF2A | myocyte enhancer factor 2A | -0.0278436 |
| VCL | vinculin | -0.0278275 |
| RPL35A | ribosomal protein L35a | -0.027816 |
| HDLBP | high density lipoprotein binding protein | -0.0277982 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0276274 |
| ATP11B | ATPase, class VI, type 11B | -0.0275191 |
| TMEM123 | transmembrane protein 123 | -0.0273745 |
| MYO6 | myosin VI | -0.0269335 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0268502 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0265936 |
| RPS5 | ribosomal protein S5 | -0.0261598 |
| WWC1 | WW and C2 domain containing 1 | -0.0258728 |
| SPAG9 | sperm associated antigen 9 | -0.0254838 |
| FLNB | filamin B, beta | -0.0254684 |
| ATP11A | ATPase, class VI, type 11A | -0.0254441 |
| VIM | vimentin | -0.025085 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0249661 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0246821 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0246769 |
| RPS25 | ribosomal protein S25 | -0.0246694 |
| LDHA | lactate dehydrogenase A | -0.0246444 |
| FBXO11 | F-box protein 11 | -0.024434 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0242511 |
| RPS19 | ribosomal protein S19 | -0.0240972 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0235555 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0234697 |
| IFI44 | interferon-induced protein 44 | -0.0230244 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0229427 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0228463 |
| TOP1 | topoisomerase (DNA) I | -0.0221899 |
| RAD21 | RAD21 homolog (S. pombe) | -0.022188 |
| OGA | O-GlcNAcase | -0.0221539 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0221347 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.021738 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0215579 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0215014 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0214804 |
| FN1 | fibronectin 1 | -0.0209986 |
| RPL12 | ribosomal protein L12 | -0.020697 |
| JMJD1C | jumonji domain containing 1C | -0.0201616 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0201306 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0201242 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0196801 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0195187 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0193578 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0190879 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0190368 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0190302 |
| RPL27A | ribosomal protein L27a | -0.0189753 |
| FTL | ferritin, light polypeptide | -0.0189548 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0189364 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0189115 |
| RPS20 | ribosomal protein S20 | -0.0188117 |
| CD2AP | CD2-associated protein | -0.018487 |
| RNF145 | ring finger protein 145 | -0.0184489 |
| ITGA6 | integrin, alpha 6 | -0.0184316 |
| MT2A | metallothionein 2A | -0.0183099 |
| MYL12B | myosin, light chain 12B, regulatory | -0.018225 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0181069 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0181007 |
| SLMAP | sarcolemma associated protein | -0.017844 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0178228 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0177879 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.017753 |
