| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benztropine (mesylate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Benztropine (mesylate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.0916255 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0842976 |
| EGFR | epidermal growth factor receptor | 0.0815345 |
| TMSB4X | thymosin beta 4, X-linked | 0.0785102 |
| VCL | vinculin | 0.0606654 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0579913 |
| HDAC9 | histone deacetylase 9 | 0.0550164 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0508002 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0496835 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.044625 |
| PKM | pyruvate kinase, muscle | 0.0443189 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0429684 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0427673 |
| PDGFC | platelet derived growth factor C | 0.0415366 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0388264 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0373219 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.036829 |
| OSMR | oncostatin M receptor | 0.0366182 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0363582 |
| TXNRD1 | thioredoxin reductase 1 | 0.036244 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0353553 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0341893 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0319788 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0311776 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0300417 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0296941 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0296444 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0284475 |
| NBEA | neurobeachin | 0.028131 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0271994 |
| DUSP4 | dual specificity phosphatase 4 | 0.0264926 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0264917 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0263919 |
| BMP10 | bone morphogenetic protein 10 | 0.0259262 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0248093 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0245294 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | 0.0243315 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0241081 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | 0.0233868 |
| EXOC6B | exocyst complex component 6B | 0.0233235 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0230154 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0224772 |
| NMD3 | NMD3 ribosome export adaptor | 0.0220976 |
| LOXL3 | lysyl oxidase-like 3 | 0.0216723 |
| RHBDD1 | rhomboid domain containing 1 | 0.021468 |
| SMYD3 | SET and MYND domain containing 3 | 0.021333 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0210382 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0203713 |
| EFNA5 | ephrin-A5 | 0.0201849 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0197813 |
| DGKH | diacylglycerol kinase, eta | 0.0197163 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | 0.0191417 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0189582 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0189298 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0187855 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0186102 |
| PLSCR1 | phospholipid scramblase 1 | 0.0185363 |
| MACROD2 | MACRO domain containing 2 | 0.0184583 |
| RIGI | RNA sensor RIG-I | 0.0183721 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0183093 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0182573 |
| EXOC4 | exocyst complex component 4 | 0.017932 |
| METTL15 | methyltransferase like 15 | 0.0178087 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0177859 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0177417 |
| PHF14 | PHD finger protein 14 | 0.0175893 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0175838 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0174921 |
| XPOT | exportin, tRNA | 0.0172573 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0171819 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0171221 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0170254 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0170241 |
| ADAR | adenosine deaminase, RNA-specific | 0.0169155 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.016632 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0165937 |
| ENO1 | enolase 1, (alpha) | 0.0164211 |
| PTEN | phosphatase and tensin homolog | 0.0163707 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.016369 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0161384 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0161228 |
| RAD51B | RAD51 paralog B | 0.0159896 |
| LRRC7 | leucine rich repeat containing 7 | 0.0159598 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0159214 |
| GLI3 | GLI family zinc finger 3 | 0.0157854 |
| SEPTIN9 | septin 9 | 0.0157801 |
| ARHGAP25 | Rho GTPase activating protein 25 | 0.0157762 |
| MYO5C | myosin VC | 0.0157636 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0157579 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0156953 |
| INVS | inversin | 0.0155787 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0155346 |
| GPHN | gephyrin | 0.0154512 |
| SATB2 | SATB homeobox 2 | 0.0154229 |
| ANK2 | ankyrin 2, neuronal | 0.0153519 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.015267 |
| MTAP | methylthioadenosine phosphorylase | 0.0152185 |
| ATXN7 | ataxin 7 | 0.0151923 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.015124 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0149794 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.153962 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0917698 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0674102 |
| GOLGA4 | golgin A4 | -0.0646022 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0603742 |
| MKI67 | marker of proliferation Ki-67 | -0.0526012 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0514906 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0485135 |
| ECT2 | epithelial cell transforming 2 | -0.0456232 |
| CENPF | centromere protein F, 350/400kDa | -0.0438301 |
| NAV2 | neuron navigator 2 | -0.0417212 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0374355 |
| QKI | QKI, KH domain containing, RNA binding | -0.0367464 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0366499 |
| TPX2 | TPX2, microtubule-associated | -0.0362429 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.034933 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0334971 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0332825 |
| DIAPH3 | diaphanous-related formin 3 | -0.033083 |
| CDC73 | cell division cycle 73 | -0.0327736 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0319395 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0319084 |
| RPS6 | ribosomal protein S6 | -0.0316974 |
| RPL35A | ribosomal protein L35a | -0.029649 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0294398 |
| ACTG1 | actin gamma 1 | -0.0285534 |
| RPL34 | ribosomal protein L34 | -0.0271791 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0262734 |
| EVI5 | ecotropic viral integration site 5 | -0.0261388 |
| RPS25 | ribosomal protein S25 | -0.0261138 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.02592 |
| FNDC3B | fibronectin type III domain containing 3B | -0.025875 |
| HJURP | Holliday junction recognition protein | -0.0255953 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0252944 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0250758 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0246837 |
| RBM25 | RNA binding motif protein 25 | -0.0246826 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0246485 |
| SEC24D | SEC24 family member D | -0.0243921 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0243718 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0241892 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0237693 |
| RPL37A | ribosomal protein L37a | -0.0237157 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0232357 |
| HELZ | helicase with zinc finger | -0.0231138 |
| MYOF | myoferlin | -0.0227234 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0226962 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.022596 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0223924 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0221615 |
| NUP58 | nucleoporin 58 | -0.0221111 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0220943 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0220337 |
| USP3 | ubiquitin specific peptidase 3 | -0.021845 |
| RHOA | ras homolog family member A | -0.0218103 |
| SEPTIN7 | septin 7 | -0.0217185 |
| RBM39 | RNA binding motif protein 39 | -0.0217118 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0216169 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0215929 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0215914 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0213434 |
| THOC2 | THO complex 2 | -0.021251 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | -0.0208184 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0204725 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0204029 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0202283 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0200941 |
| RRM2 | ribonucleotide reductase M2 | -0.0200394 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0200126 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0198423 |
| RPS23 | ribosomal protein S23 | -0.019805 |
| S100A9 | S100 calcium binding protein A9 | -0.0197763 |
| NFIA | nuclear factor I/A | -0.0197433 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0197397 |
| ANLN | anillin, actin binding protein | -0.019718 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0197173 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0196569 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0195425 |
| CENPE | centromere protein E, 312kDa | -0.0192117 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0190709 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0189158 |
| RPS16 | ribosomal protein S16 | -0.0188762 |
| EZR | ezrin | -0.018827 |
| S100A6 | S100 calcium binding protein A6 | -0.0187824 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0186355 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0183664 |
| CTBP2 | C-terminal binding protein 2 | -0.0182699 |
| FNIP1 | folliculin interacting protein 1 | -0.0182301 |
| RPL11 | ribosomal protein L11 | -0.0181517 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.018124 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0179736 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0179393 |
| ATOSA | atos homolog A | -0.0179094 |
| RPLP1 | ribosomal protein, large, P1 | -0.0179032 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.017895 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0178928 |
| TFG | TRK-fused gene | -0.0177765 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0176838 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.017671 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0175877 |
