| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benztropine (mesylate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Benztropine (mesylate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0918478 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.084251 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0744374 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0741487 |
| TPX2 | TPX2, microtubule-associated | 0.0611456 |
| GOLGA4 | golgin A4 | 0.0564152 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0508196 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0498265 |
| ZNF292 | zinc finger protein 292 | 0.0492706 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0492207 |
| YBX3 | Y box binding protein 3 | 0.0476547 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.04715 |
| WAC | WW domain containing adaptor with coiled-coil | 0.046188 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0459021 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0458902 |
| SETD5 | SET domain containing 5 | 0.0458051 |
| DIAPH3 | diaphanous-related formin 3 | 0.0450556 |
| ANLN | anillin, actin binding protein | 0.0448701 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0448033 |
| CENPF | centromere protein F, 350/400kDa | 0.044483 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0412374 |
| NUP58 | nucleoporin 58 | 0.0407096 |
| KIAA1958 | KIAA1958 | 0.0406499 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0405796 |
| HELZ | helicase with zinc finger | 0.0398843 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0389776 |
| TXNRD1 | thioredoxin reductase 1 | 0.0366617 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0359254 |
| SPAG9 | sperm associated antigen 9 | 0.0357067 |
| ECT2 | epithelial cell transforming 2 | 0.0354357 |
| COG5 | component of oligomeric golgi complex 5 | 0.035303 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0351593 |
| PTMA | prothymosin, alpha | 0.034846 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0348422 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0342812 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0339076 |
| SGO2 | shugoshin 2 | 0.0338844 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0337374 |
| RBM39 | RNA binding motif protein 39 | 0.03236 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.032262 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0320965 |
| NKTR | natural killer cell triggering receptor | 0.0317539 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0315768 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0315605 |
| BRD8 | bromodomain containing 8 | 0.0312224 |
| KIF5B | kinesin family member 5B | 0.0310238 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0308353 |
| RPL23 | ribosomal protein L23 | 0.0304179 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0302067 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0301568 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0301334 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0296992 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0294397 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0294014 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0293512 |
| TNPO1 | transportin 1 | 0.0289594 |
| TMEM263 | transmembrane protein 263 | 0.0289553 |
| ARRDC3 | arrestin domain containing 3 | 0.0288664 |
| PHF20 | PHD finger protein 20 | 0.0288392 |
| BRD4 | bromodomain containing 4 | 0.0286738 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0286482 |
| SET | SET nuclear proto-oncogene | 0.0284966 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0284068 |
| OGA | O-GlcNAcase | 0.0283884 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.028387 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0281031 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0278555 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0278203 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0276953 |
| RLF | rearranged L-myc fusion | 0.0275803 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0274618 |
| YBX1 | Y box binding protein 1 | 0.0272186 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0271588 |
| RDX | radixin | 0.0270515 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0268287 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0267877 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0264056 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0261522 |
| KLHL24 | kelch-like family member 24 | 0.0258453 |
| NCKAP1 | NCK-associated protein 1 | 0.0257069 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0255499 |
| RPS3 | ribosomal protein S3 | 0.0255075 |
| CEP290 | centrosomal protein 290kDa | 0.0254216 |
| RBM27 | RNA binding motif protein 27 | 0.0253243 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0252443 |
| SQSTM1 | sequestosome 1 | 0.0248744 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.024862 |
| YAP1 | Yes-associated protein 1 | 0.024842 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0243871 |
| CALU | calumenin | 0.0242404 |
| TMEM41B | transmembrane protein 41B | 0.0240571 |
| RPL35 | ribosomal protein L35 | 0.0239069 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0234074 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0233059 |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing | 0.0232587 |
| TTK | TTK protein kinase | 0.0232138 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0231935 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0231611 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0230286 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0228557 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | -0.100282 |
| FNDC3B | fibronectin type III domain containing 3B | -0.09359 |
| TMSB10 | thymosin beta 10 | -0.0933403 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0774283 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0726639 |
| FLNB | filamin B, beta | -0.0589768 |
| LDHA | lactate dehydrogenase A | -0.0570088 |
| FMNL2 | formin-like 2 | -0.056817 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.056785 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0538647 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0521587 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0500633 |
| DST | dystonin | -0.0479602 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0465803 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0463424 |
| PRSS23 | protease, serine, 23 | -0.0455109 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0452081 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0447031 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0439526 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0436066 |
| RIGI | RNA sensor RIG-I | -0.0425216 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0422356 |
| PTK2 | protein tyrosine kinase 2 | -0.0421758 |
| ATXN1 | ataxin 1 | -0.0411753 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0408581 |
| PRR16 | proline rich 16 | -0.0408357 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.038928 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0384632 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0365777 |
| DNER | delta/notch-like EGF repeat containing | -0.0363558 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0350346 |
| PODXL | podocalyxin-like | -0.0343515 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.034187 |
| PRKCA | protein kinase C, alpha | -0.0339262 |
| NDRG1 | N-myc downstream regulated 1 | -0.0338787 |
| CD44 | CD44 molecule (Indian blood group) | -0.0336847 |
| OSMR | oncostatin M receptor | -0.0334215 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0332497 |
| RAI14 | retinoic acid induced 14 | -0.0327535 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0326801 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0319902 |
| ANGPTL4 | angiopoietin-like 4 | -0.0317075 |
| COL5A1 | collagen, type V, alpha 1 | -0.0315197 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.031138 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0304011 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0297464 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0292066 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0290807 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0288063 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0281485 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0280545 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0280307 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0279788 |
| VCL | vinculin | -0.0278775 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0278008 |
| MAP1B | microtubule-associated protein 1B | -0.0273229 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.027278 |
| VIM | vimentin | -0.0272456 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0269805 |
| PCED1B | PC-esterase domain containing 1B | -0.0269519 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0268451 |
| PKM | pyruvate kinase, muscle | -0.0266368 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0264326 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0259458 |
| CCDC91 | coiled-coil domain containing 91 | -0.0257886 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.025743 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0253898 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0253839 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0248049 |
| FMN1 | formin 1 | -0.0247917 |
| AEBP2 | AE binding protein 2 | -0.0247309 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0243251 |
| SYNJ2 | synaptojanin 2 | -0.024261 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0242167 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0239387 |
| LAMB1 | laminin, beta 1 | -0.0237995 |
| POTEF | POTE ankyrin domain family, member F | -0.0237982 |
| INTS6 | integrator complex subunit 6 | -0.0233913 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0229746 |
| SVIL | supervillin | -0.0225268 |
| NAV3 | neuron navigator 3 | -0.0224779 |
| NALCN | sodium leak channel, non selective | -0.0224741 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0224073 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0223872 |
| KIAA1671 | KIAA1671 | -0.0223423 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0222301 |
| PLEK2 | pleckstrin 2 | -0.0221146 |
| CMIP | c-Maf inducing protein | -0.0219873 |
| ANO6 | anoctamin 6 | -0.0218472 |
| LMO7 | LIM domain 7 | -0.0218062 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0217538 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0217205 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0217083 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.021662 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0214562 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | -0.021389 |
| AK1 | adenylate kinase 1 | -0.0210759 |
| ABR | active BCR-related | -0.0209833 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0207502 |
| UTRN | utrophin | -0.0206798 |
