| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benztropine (mesylate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Benztropine (mesylate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD36 | CD36 molecule (thrombospondin receptor) | 0.133607 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0805427 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0598628 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0598343 |
| DSPP | dentin sialophosphoprotein | 0.0573486 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.056603 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0563463 |
| FAT1 | FAT atypical cadherin 1 | 0.0549229 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0529569 |
| LAMC2 | laminin, gamma 2 | 0.0525463 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0466065 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0444328 |
| ATXN1 | ataxin 1 | 0.0434588 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0421801 |
| FLOT1 | flotillin 1 | 0.0409723 |
| AREG | amphiregulin | 0.0399651 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0391777 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0389457 |
| EGFR | epidermal growth factor receptor | 0.0383252 |
| CPOX | coproporphyrinogen oxidase | 0.0366775 |
| RAD51B | RAD51 paralog B | 0.0360892 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.034749 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0333985 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0324757 |
| FERMT1 | fermitin family member 1 | 0.0324105 |
| EPHA2 | EPH receptor A2 | 0.0313779 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0290888 |
| EZR | ezrin | 0.0285564 |
| ANXA1 | annexin A1 | 0.0269659 |
| FOSL1 | FOS-like antigen 1 | 0.0267654 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0267216 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0257717 |
| ANXA11 | annexin A11 | 0.0256837 |
| AHNAK | AHNAK nucleoprotein | 0.0250766 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0246723 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0246214 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.0239758 |
| CALR | calreticulin | 0.0236874 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0231387 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0231215 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0226342 |
| ZFP36 | ZFP36 ring finger protein | 0.0222194 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.022092 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0220759 |
| BBX | bobby sox homolog (Drosophila) | 0.0214511 |
| EREG | epiregulin | 0.021277 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.021172 |
| ARRDC3 | arrestin domain containing 3 | 0.0210007 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0209075 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.020843 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.020744 |
| FHIT | fragile histidine triad | 0.0204722 |
| FHL2 | four and a half LIM domains 2 | 0.0198832 |
| RUNX2 | runt-related transcription factor 2 | 0.0198023 |
| FLNA | filamin A, alpha | 0.0197858 |
| ANXA2 | annexin A2 | 0.0197819 |
| CANX | calnexin | 0.0196518 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0194992 |
| ZNF292 | zinc finger protein 292 | 0.0190163 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0188656 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0188441 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0188033 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0187232 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0185628 |
| TPM3 | tropomyosin 3 | 0.0183756 |
| SPAG9 | sperm associated antigen 9 | 0.0182955 |
| HIP1 | huntingtin interacting protein 1 | 0.0182147 |
| CD9 | CD9 molecule | 0.0181714 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0180879 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0178152 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0177469 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0175962 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0174933 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | 0.0172121 |
| EFNB2 | ephrin-B2 | 0.0171213 |
| DST | dystonin | 0.0169363 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0167588 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0163182 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0161116 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.015979 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.015898 |
| TENM3 | teneurin transmembrane protein 3 | 0.0157502 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0157196 |
| TPM4 | tropomyosin 4 | 0.0156977 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0155339 |
| SPON1 | spondin 1, extracellular matrix protein | 0.0155061 |
| BCL2L1 | BCL2-like 1 | 0.0154829 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 | 0.0153357 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0153018 |
| RPL3 | ribosomal protein L3 | 0.0149658 |
| ENO1 | enolase 1, (alpha) | 0.014795 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0147767 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0147688 |
| NCKAP1 | NCK-associated protein 1 | 0.0146391 |
| PRELID2 | PRELI domain containing 2 | 0.0146087 |
| NABP1 | nucleic acid binding protein 1 | 0.0142933 |
| VEGFA | vascular endothelial growth factor A | 0.014223 |
| RPTN | repetin | 0.0142111 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0140071 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0139321 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.12562 |
| RPS6 | ribosomal protein S6 | -0.0868838 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0662093 |
| PTMA | prothymosin, alpha | -0.0638374 |
| RPS24 | ribosomal protein S24 | -0.0598874 |
| RPLP1 | ribosomal protein, large, P1 | -0.0515472 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0513369 |
| IER3 | immediate early response 3 | -0.0452994 |
| RPS19 | ribosomal protein S19 | -0.0407064 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0399698 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0361626 |
| RPLP0 | ribosomal protein, large, P0 | -0.03452 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0339664 |
| RPS4X | ribosomal protein S4, X-linked | -0.0333687 |
| RPL32 | ribosomal protein L32 | -0.0327766 |
| RPL23 | ribosomal protein L23 | -0.0320031 |
| RPL12 | ribosomal protein L12 | -0.0316603 |
| RPL34 | ribosomal protein L34 | -0.0297074 |
| ACTG1 | actin gamma 1 | -0.0295278 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0286288 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0281729 |
| LDHA | lactate dehydrogenase A | -0.0279497 |
| RPL11 | ribosomal protein L11 | -0.0271529 |
| OXSR1 | oxidative stress responsive 1 | -0.0269325 |
| RCOR1 | REST corepressor 1 | -0.0265005 |
| RPL35A | ribosomal protein L35a | -0.0261735 |
| RPL9 | ribosomal protein L9 | -0.0261684 |
| RPL4 | ribosomal protein L4 | -0.0254194 |
| RPS17 | ribosomal protein S17 | -0.0249657 |
| RPS8 | ribosomal protein S8 | -0.0248698 |
| RPS25 | ribosomal protein S25 | -0.0248427 |
| RPL31 | ribosomal protein L31 | -0.0242472 |
| RPLP2 | ribosomal protein, large, P2 | -0.0241563 |
| NPR2 | natriuretic peptide receptor 2 | -0.0229322 |
| EGR1 | early growth response 1 | -0.0220012 |
| RPL13A | ribosomal protein L13a | -0.0216997 |
| TUBB | tubulin, beta class I | -0.0210565 |
| RPL7 | ribosomal protein L7 | -0.0205661 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0203238 |
| RPS28 | ribosomal protein S28 | -0.0203026 |
| ARF1 | ADP-ribosylation factor 1 | -0.0202607 |
| RPS5 | ribosomal protein S5 | -0.0201325 |
| S100A6 | S100 calcium binding protein A6 | -0.020031 |
| RPL26 | ribosomal protein L26 | -0.019974 |
| FTL | ferritin, light polypeptide | -0.0199708 |
| RPL35 | ribosomal protein L35 | -0.0192095 |
| S100A10 | S100 calcium binding protein A10 | -0.0190764 |
| RPL30 | ribosomal protein L30 | -0.0190187 |
| RPL36 | ribosomal protein L36 | -0.0188631 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0188387 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.018721 |
| RPS20 | ribosomal protein S20 | -0.0185034 |
| RPS27A | ribosomal protein S27a | -0.017997 |
| RPS16 | ribosomal protein S16 | -0.0179405 |
| RPS15 | ribosomal protein S15 | -0.0178505 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0177509 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0171892 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.017119 |
| RNF145 | ring finger protein 145 | -0.0170235 |
| RPL27A | ribosomal protein L27a | -0.0164021 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0159761 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0157165 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0156683 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0155723 |
| PERP | PERP, TP53 apoptosis effector | -0.0154551 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0154343 |
| RBM39 | RNA binding motif protein 39 | -0.0153141 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0150692 |
| RBM25 | RNA binding motif protein 25 | -0.0150312 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0148253 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0147858 |
| RPL19 | ribosomal protein L19 | -0.0146991 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0144896 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0143747 |
| LDHB | lactate dehydrogenase B | -0.0143627 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0142668 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0141876 |
| RPS27 | ribosomal protein S27 | -0.0140437 |
| CEP350 | centrosomal protein 350kDa | -0.0139158 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0139063 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0138245 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0137223 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0137174 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0133869 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.013351 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0132544 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0132329 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0132215 |
| MT1X | metallothionein 1X | -0.0132202 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.013127 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0131215 |
| MORF4L2 | mortality factor 4 like 2 | -0.0131011 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0130983 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0129714 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0129646 |
| TET3 | tet methylcytosine dioxygenase 3 | -0.0129646 |
| HMGA1 | high mobility group AT-hook 1 | -0.0128669 |
| KITLG | KIT ligand | -0.0128162 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0128109 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0126398 |
