| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benztropine (mesylate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Benztropine (mesylate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.114555 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.110969 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0780731 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0693325 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0659707 |
| CANX | calnexin | 0.0555407 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0554296 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0523533 |
| SNX9 | sorting nexin 9 | 0.0491952 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0485126 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0469413 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.046329 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0455411 |
| DSPP | dentin sialophosphoprotein | 0.0439477 |
| AHNAK | AHNAK nucleoprotein | 0.0430438 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0395126 |
| ZNF292 | zinc finger protein 292 | 0.0385014 |
| SYT1 | synaptotagmin I | 0.0381601 |
| EZR | ezrin | 0.0367114 |
| XPO1 | exportin 1 | 0.0366931 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0361618 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.036138 |
| PROX1 | prospero homeobox 1 | 0.0358341 |
| ENO1 | enolase 1, (alpha) | 0.0357914 |
| OGA | O-GlcNAcase | 0.0356916 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0353755 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0343782 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0343705 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0340276 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0335735 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0334574 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0332922 |
| SETD5 | SET domain containing 5 | 0.0331778 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0325043 |
| ETNK1 | ethanolamine kinase 1 | 0.0323835 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0322792 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.032266 |
| ZFR | zinc finger RNA binding protein | 0.0320429 |
| ATXN1 | ataxin 1 | 0.0318103 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.031297 |
| JMJD1C | jumonji domain containing 1C | 0.0312724 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0309974 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0309198 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0308972 |
| AOPEP | aminopeptidase O (putative) | 0.030872 |
| TMEM41B | transmembrane protein 41B | 0.0305353 |
| TNS4 | tensin 4 | 0.0303302 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0296258 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0295905 |
| TPM3 | tropomyosin 3 | 0.0292509 |
| GOLGA4 | golgin A4 | 0.0288797 |
| FOXP1 | forkhead box P1 | 0.0286729 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0286155 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0284419 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0279903 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0279579 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0279178 |
| TXNIP | thioredoxin interacting protein | 0.0279081 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0275779 |
| UBC | ubiquitin C | 0.0272247 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | 0.0270413 |
| CDK8 | cyclin-dependent kinase 8 | 0.0267643 |
| STAG2 | stromal antigen 2 | 0.0267636 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0267627 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.02676 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.026684 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0265303 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0265086 |
| RUNX1 | runt-related transcription factor 1 | 0.026439 |
| USP3 | ubiquitin specific peptidase 3 | 0.0261951 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0259333 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0258968 |
| H1-0 | H1.0 linker histone | 0.0256889 |
| HSPA8 | heat shock 70kDa protein 8 | 0.025253 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0251523 |
| PCM1 | pericentriolar material 1 | 0.0251355 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0250474 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0249831 |
| ARRDC3 | arrestin domain containing 3 | 0.0249614 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0248341 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0247936 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0246683 |
| SPATA13 | spermatogenesis associated 13 | 0.0244933 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0242525 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0241667 |
| MACC1 | metastasis associated in colon cancer 1 | 0.024131 |
| PHF21A | PHD finger protein 21A | 0.0239362 |
| SBF2 | SET binding factor 2 | 0.0238969 |
| VGLL4 | vestigial-like family member 4 | 0.0237418 |
| YTHDC1 | YTH domain containing 1 | 0.0236694 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0235685 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0235354 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0235142 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0235073 |
| UTRN | utrophin | 0.0235004 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0234733 |
| MAP1B | microtubule-associated protein 1B | 0.0234326 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0232631 |
| AFDN | afadin, adherens junction formation factor | 0.0232498 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0231912 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.162077 |
| NAV2 | neuron navigator 2 | -0.145501 |
| TMSB10 | thymosin beta 10 | -0.099497 |
| CDH13 | cadherin 13 | -0.0784687 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0779726 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0774933 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0754383 |
| ASPH | aspartate beta-hydroxylase | -0.0735753 |
| INTS6 | integrator complex subunit 6 | -0.0687754 |
| VCL | vinculin | -0.065478 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0603992 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0504019 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0489326 |
| CCND1 | cyclin D1 | -0.0483144 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0467589 |
| FRMD5 | FERM domain containing 5 | -0.0451551 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.044606 |
| WWOX | WW domain containing oxidoreductase | -0.0427562 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0424106 |
| RPLP1 | ribosomal protein, large, P1 | -0.0421393 |
| RPS24 | ribosomal protein S24 | -0.0412526 |
| RPL23 | ribosomal protein L23 | -0.04065 |
| RPL35A | ribosomal protein L35a | -0.0399222 |
| PTMA | prothymosin, alpha | -0.0391376 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.038341 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0375611 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.037196 |
| RAD51B | RAD51 paralog B | -0.0353824 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0351972 |
| CDK6 | cyclin-dependent kinase 6 | -0.0337135 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0327798 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0318237 |
| MT2A | metallothionein 2A | -0.0291892 |
| HMGA1 | high mobility group AT-hook 1 | -0.0291784 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.029172 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0284749 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0280139 |
| MYOF | myoferlin | -0.0273914 |
| UBAP2 | ubiquitin associated protein 2 | -0.0272582 |
| RPL37A | ribosomal protein L37a | -0.0270792 |
| FHIT | fragile histidine triad | -0.0268296 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0257888 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0256883 |
| RPS19 | ribosomal protein S19 | -0.0256845 |
| LDHA | lactate dehydrogenase A | -0.0252067 |
| FLNB | filamin B, beta | -0.0251849 |
| RPL9 | ribosomal protein L9 | -0.0251043 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0250456 |
| VIM | vimentin | -0.0249384 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0245572 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.023762 |
| ACTG1 | actin gamma 1 | -0.0237495 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.023146 |
| EXOC4 | exocyst complex component 4 | -0.022562 |
| RCOR1 | REST corepressor 1 | -0.0221382 |
| HMGB1 | high mobility group box 1 | -0.0220248 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0217937 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.021763 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0216159 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.021598 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0207692 |
| RPL38 | ribosomal protein L38 | -0.0198361 |
| FUS | FUS RNA binding protein | -0.0197319 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0192779 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.019265 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0190168 |
| RPS23 | ribosomal protein S23 | -0.0189088 |
| ACTN1 | actinin, alpha 1 | -0.0187837 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0187368 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0187008 |
| NABP1 | nucleic acid binding protein 1 | -0.018644 |
| HDAC4 | histone deacetylase 4 | -0.0185286 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0184334 |
| RPL12 | ribosomal protein L12 | -0.0183545 |
| CD44 | CD44 molecule (Indian blood group) | -0.0181428 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0180824 |
| RPLP2 | ribosomal protein, large, P2 | -0.0178585 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0177084 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0176915 |
| RPL26 | ribosomal protein L26 | -0.017689 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0174206 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0174079 |
| RPS20 | ribosomal protein S20 | -0.0173117 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0173035 |
| RPL31 | ribosomal protein L31 | -0.0172914 |
| NOP56 | NOP56 ribonucleoprotein | -0.0171036 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0170772 |
| COMMD10 | COMM domain containing 10 | -0.016931 |
| PCNX4 | pecanex 4 | -0.0169191 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0169099 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0167489 |
| RCC1 | regulator of chromosome condensation 1 | -0.0163436 |
| CDK13 | cyclin-dependent kinase 13 | -0.0160791 |
| LASP1 | LIM and SH3 protein 1 | -0.0160608 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0156955 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | -0.0155857 |
| GLI3 | GLI family zinc finger 3 | -0.0154487 |
| RPL34 | ribosomal protein L34 | -0.0154308 |
| ABR | active BCR-related | -0.0153645 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0153359 |
