| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine (dihydrochloride)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.151621 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.112545 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.109658 |
| LDHA | lactate dehydrogenase A | 0.0823735 |
| DST | dystonin | 0.0673057 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0659351 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0658415 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0569385 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0539732 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0516513 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0506341 |
| TPI1 | triosephosphate isomerase 1 | 0.0504623 |
| ACTG1 | actin gamma 1 | 0.050005 |
| PLEC | plectin | 0.049524 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0486115 |
| HLA-A | major histocompatibility complex, class I, A | 0.0481675 |
| PCBP2 | poly(rC) binding protein 2 | 0.0476943 |
| CENPF | centromere protein F, 350/400kDa | 0.0476927 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0457841 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0449673 |
| RPL35A | ribosomal protein L35a | 0.0436058 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.043551 |
| RHOA | ras homolog family member A | 0.0415119 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 0.0403268 |
| XPO1 | exportin 1 | 0.039795 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0380818 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0377377 |
| LDHB | lactate dehydrogenase B | 0.0365427 |
| LMO7 | LIM domain 7 | 0.0365138 |
| TPM4 | tropomyosin 4 | 0.0351264 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0350143 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.034301 |
| TXNRD1 | thioredoxin reductase 1 | 0.0342619 |
| WDR43 | WD repeat domain 43 | 0.0337029 |
| CCNL1 | cyclin L1 | 0.0332014 |
| POTEF | POTE ankyrin domain family, member F | 0.0326243 |
| TMEM123 | transmembrane protein 123 | 0.0326162 |
| ENO1 | enolase 1, (alpha) | 0.0324174 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0316884 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0313668 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0308881 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0305422 |
| RPL3 | ribosomal protein L3 | 0.0303315 |
| TUBB | tubulin, beta class I | 0.0298431 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0295987 |
| PGK1 | phosphoglycerate kinase 1 | 0.0295937 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.029118 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0289878 |
| PFN1 | profilin 1 | 0.0288746 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.028342 |
| PKM | pyruvate kinase, muscle | 0.0280862 |
| WDR45B | WD repeat domain 45B | 0.0278622 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0277523 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0277254 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0270487 |
| DEK | DEK proto-oncogene | 0.0268967 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0268825 |
| TGM2 | transglutaminase 2 | 0.0268583 |
| EZR | ezrin | 0.0268579 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0267512 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0264807 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0264013 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.026276 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.026178 |
| MATR3 | matrin 3 | 0.0260949 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0260883 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0256872 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0253274 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0253232 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.02529 |
| AXIN2 | axin 2 | 0.0252331 |
| CLDND1 | claudin domain containing 1 | 0.0251256 |
| RNF213 | ring finger protein 213 | 0.0251162 |
| NHSL1 | NHS-like 1 | 0.0247689 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0247568 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.0246997 |
| CCND1 | cyclin D1 | 0.0245534 |
| ZNF148 | zinc finger protein 148 | 0.0242018 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0241387 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0241078 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0240568 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0240473 |
| CCDC200 | coiled-coil domain containing 200 | 0.0239869 |
| MKI67 | marker of proliferation Ki-67 | 0.0239343 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0237408 |
| GNAS | GNAS complex locus | 0.0236585 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0235444 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0232985 |
| CAVIN1 | caveolae associated protein 1 | 0.0231352 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0231011 |
| EGR1 | early growth response 1 | 0.0223202 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0223185 |
| TFG | TRK-fused gene | 0.0219907 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0219742 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0217414 |
| MSI2 | musashi RNA-binding protein 2 | 0.0217373 |
| NUP58 | nucleoporin 58 | 0.0209124 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.020868 |
| ECT2 | epithelial cell transforming 2 | 0.0207648 |
| RPS21 | ribosomal protein S21 | 0.0206315 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | -0.140239 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.126173 |
| RPS2 | ribosomal protein S2 | -0.119887 |
| RPS12 | ribosomal protein S12 | -0.115509 |
| TMSB10 | thymosin beta 10 | -0.100368 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0908248 |
| RPS6 | ribosomal protein S6 | -0.0845819 |
| HMGA2 | high mobility group AT-hook 2 | -0.0840534 |
| PCDH7 | protocadherin 7 | -0.0780069 |
| JMJD1C | jumonji domain containing 1C | -0.0736709 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0723105 |
| RPL12 | ribosomal protein L12 | -0.0706444 |
| RPL26 | ribosomal protein L26 | -0.060964 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0577719 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0575648 |
| MMP12 | matrix metallopeptidase 12 | -0.0568003 |
| FTL | ferritin, light polypeptide | -0.0529996 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0520472 |
| ASPH | aspartate beta-hydroxylase | -0.0507198 |
| RPS19 | ribosomal protein S19 | -0.0501833 |
| RPLP2 | ribosomal protein, large, P2 | -0.0496972 |
| ZNF804A | zinc finger protein 804A | -0.0489002 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0488898 |
| RPS3 | ribosomal protein S3 | -0.0481716 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0467517 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0465833 |
| RPS29 | ribosomal protein S29 | -0.0456878 |
| RPL11 | ribosomal protein L11 | -0.0442727 |
| BCHE | butyrylcholinesterase | -0.043814 |
| EHBP1 | EH domain binding protein 1 | -0.0430762 |
| CLTC | clathrin, heavy chain (Hc) | -0.04256 |
| RPL19 | ribosomal protein L19 | -0.0410598 |
| RPL36 | ribosomal protein L36 | -0.040296 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0396963 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0384937 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0384558 |
| MTAP | methylthioadenosine phosphorylase | -0.0384373 |
| VMP1 | vacuole membrane protein 1 | -0.0383074 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.038182 |
| RPL37 | ribosomal protein L37 | -0.036971 |
| RPL31 | ribosomal protein L31 | -0.0362813 |
| RPL37A | ribosomal protein L37a | -0.0357021 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0352419 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.03504 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0342635 |
| HDAC9 | histone deacetylase 9 | -0.0332999 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0329826 |
| RPS16 | ribosomal protein S16 | -0.0328331 |
| RPL9 | ribosomal protein L9 | -0.0317047 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0315053 |
| RPS27 | ribosomal protein S27 | -0.0308083 |
| USP34 | ubiquitin specific peptidase 34 | -0.030712 |
| RPLP1 | ribosomal protein, large, P1 | -0.0302678 |
| INTS6 | integrator complex subunit 6 | -0.0301895 |
| RPS7 | ribosomal protein S7 | -0.0299999 |
| RPS27A | ribosomal protein S27a | -0.0298105 |
| PRKCI | protein kinase C, iota | -0.0296019 |
| NLGN1 | neuroligin 1 | -0.0293567 |
| SETD5 | SET domain containing 5 | -0.0287402 |
| RPS25 | ribosomal protein S25 | -0.0286723 |
| RPL36A | ribosomal protein L36a | -0.0284319 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0278513 |
| RPS17 | ribosomal protein S17 | -0.0276267 |
| CANX | calnexin | -0.0275985 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0275757 |
| RASA2 | RAS p21 protein activator 2 | -0.0267976 |
| RPS23 | ribosomal protein S23 | -0.0267674 |
| NABP1 | nucleic acid binding protein 1 | -0.0266711 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0262377 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.025884 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0258055 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0253743 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0244765 |
| RPS5 | ribosomal protein S5 | -0.0239028 |
| RPS8 | ribosomal protein S8 | -0.0238248 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0237125 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0235962 |
| RPL7 | ribosomal protein L7 | -0.0233262 |
| GOLGA4 | golgin A4 | -0.0232723 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0232204 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0230823 |
| HMGB1 | high mobility group box 1 | -0.0228699 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.0228358 |
| MYPN | myopalladin | -0.0226716 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.022659 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | -0.0226584 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.022552 |
| YAP1 | Yes-associated protein 1 | -0.0221909 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0220588 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0220003 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0219671 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0216662 |
| RPL35 | ribosomal protein L35 | -0.0214612 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0214249 |
| WWOX | WW domain containing oxidoreductase | -0.0212923 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0212299 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0212198 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0210716 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0208283 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0207782 |
