| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine (dihydrochloride)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ANXA2 | annexin A2 | 0.183071 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.128646 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0995346 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0889619 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0881952 |
| EGFR | epidermal growth factor receptor | 0.0834599 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0785024 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0700004 |
| PCBP2 | poly(rC) binding protein 2 | 0.0698386 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0657278 |
| VCL | vinculin | 0.0644808 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0642086 |
| SPAG9 | sperm associated antigen 9 | 0.0601831 |
| NAV2 | neuron navigator 2 | 0.0588694 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0569885 |
| CLTC | clathrin, heavy chain (Hc) | 0.0563349 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0543895 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.052964 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0528166 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0499424 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.049204 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0469054 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0466623 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0460553 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0460178 |
| MYOF | myoferlin | 0.0455245 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0454014 |
| RTN4 | reticulon 4 | 0.0453276 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0439014 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0434579 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0432385 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.042305 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0414749 |
| PKM | pyruvate kinase, muscle | 0.0410813 |
| CTBP2 | C-terminal binding protein 2 | 0.0406617 |
| GOLGB1 | golgin B1 | 0.040501 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0404124 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0403956 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0399756 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0397933 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0397876 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0396396 |
| UBC | ubiquitin C | 0.0395677 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.039483 |
| RND3 | Rho family GTPase 3 | 0.0393636 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0384139 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0383688 |
| ANXA5 | annexin A5 | 0.0380664 |
| CALU | calumenin | 0.0380482 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0377226 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0375921 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.03743 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0368208 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0367957 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0364489 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0364079 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0361333 |
| ENO1 | enolase 1, (alpha) | 0.0360736 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0358814 |
| ZNF207 | zinc finger protein 207 | 0.0352803 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0350001 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0347316 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0346895 |
| MYO1E | myosin IE | 0.0346787 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0346658 |
| FLNA | filamin A, alpha | 0.0342012 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0341612 |
| GPATCH2L | G patch domain containing 2-like | 0.0341184 |
| MYO1B | myosin IB | 0.0334741 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0329623 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0328829 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0327558 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0327352 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0320002 |
| ECT2 | epithelial cell transforming 2 | 0.0318627 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0315609 |
| WDR43 | WD repeat domain 43 | 0.0309198 |
| AHR | aryl hydrocarbon receptor | 0.0304271 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0301728 |
| CLINT1 | clathrin interactor 1 | 0.0301578 |
| CMIP | c-Maf inducing protein | 0.029913 |
| AUTS2 | autism susceptibility candidate 2 | 0.0299127 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0298825 |
| RASA2 | RAS p21 protein activator 2 | 0.0298235 |
| SUCO | SUN domain containing ossification factor | 0.0297195 |
| SRP54 | signal recognition particle 54kDa | 0.0295912 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0294913 |
| GOSR1 | golgi SNAP receptor complex member 1 | 0.0292768 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0290512 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0287088 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0285383 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.028421 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0283659 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0282636 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0280818 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0278671 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0278512 |
| GPC6 | glypican 6 | 0.0277767 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0277532 |
| MORF4L2 | mortality factor 4 like 2 | 0.0277155 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.253102 |
| MT2A | metallothionein 2A | -0.218979 |
| RPS19 | ribosomal protein S19 | -0.12154 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.119315 |
| FTL | ferritin, light polypeptide | -0.112136 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.102841 |
| MT1X | metallothionein 1X | -0.0968317 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0742616 |
| RPLP1 | ribosomal protein, large, P1 | -0.0676451 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0648908 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0646256 |
| PDE10A | phosphodiesterase 10A | -0.0640666 |
| RPL26 | ribosomal protein L26 | -0.0550054 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0530464 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0519206 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0515649 |
| RPS3 | ribosomal protein S3 | -0.0510897 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0503046 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0488707 |
| KYNU | kynureninase | -0.0478351 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0473711 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0448939 |
| SMAD3 | SMAD family member 3 | -0.0443268 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0442275 |
| RPL12 | ribosomal protein L12 | -0.0430889 |
| RPL13A | ribosomal protein L13a | -0.0425994 |
| CA12 | carbonic anhydrase XII | -0.0421248 |
| RPL19 | ribosomal protein L19 | -0.0416377 |
| PFN1 | profilin 1 | -0.0390615 |
| RNF213 | ring finger protein 213 | -0.0383701 |
| RPLP2 | ribosomal protein, large, P2 | -0.0382604 |
| BMERB1 | bMERB domain containing 1 | -0.0382526 |
| TPM1 | tropomyosin 1 (alpha) | -0.0373136 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0367057 |
| B2M | beta-2-microglobulin | -0.0361878 |
| RPL37A | ribosomal protein L37a | -0.0359656 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.035594 |
| RPL38 | ribosomal protein L38 | -0.0350495 |
| RPL28 | ribosomal protein L28 | -0.0340362 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0339169 |
| RPS14 | ribosomal protein S14 | -0.0338937 |
| POTEF | POTE ankyrin domain family, member F | -0.0333285 |
| RPL23 | ribosomal protein L23 | -0.0332433 |
| OSMR | oncostatin M receptor | -0.0331826 |
| RPS21 | ribosomal protein S21 | -0.0321831 |
| RPL18 | ribosomal protein L18 | -0.0320907 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0320478 |
| RPS27A | ribosomal protein S27a | -0.0306836 |
| HLA-B | major histocompatibility complex, class I, B | -0.0303669 |
| RPS6 | ribosomal protein S6 | -0.0303103 |
| RPS27 | ribosomal protein S27 | -0.0302175 |
| PTMA | prothymosin, alpha | -0.0301643 |
| TMSB4X | thymosin beta 4, X-linked | -0.029918 |
| YBX3 | Y box binding protein 3 | -0.029909 |
| RPL31 | ribosomal protein L31 | -0.0296259 |
| RPL36 | ribosomal protein L36 | -0.028808 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0287832 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0286865 |
| CCNL1 | cyclin L1 | -0.0285284 |
| RPL4 | ribosomal protein L4 | -0.0283919 |
| RAI14 | retinoic acid induced 14 | -0.0282587 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0260067 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0259452 |
| RPS29 | ribosomal protein S29 | -0.0250246 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0250214 |
| RPL36A | ribosomal protein L36a | -0.0248354 |
| VIM | vimentin | -0.0247256 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0247191 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0244846 |
| NDRG1 | N-myc downstream regulated 1 | -0.0243909 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0242123 |
| TNS3 | tensin 3 | -0.0237916 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0237506 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0235402 |
| RPS13 | ribosomal protein S13 | -0.02291 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0227532 |
| NTN4 | netrin 4 | -0.0225519 |
| TXNRD1 | thioredoxin reductase 1 | -0.0223958 |
| KRT81 | keratin 81, type II | -0.0223007 |
| NRP1 | neuropilin 1 | -0.0218509 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0216871 |
| RPS12 | ribosomal protein S12 | -0.0216442 |
| RPS8 | ribosomal protein S8 | -0.0214812 |
| PGK1 | phosphoglycerate kinase 1 | -0.0212712 |
| RPL37 | ribosomal protein L37 | -0.0212526 |
| AXL | AXL receptor tyrosine kinase | -0.0212469 |
| CYTH1 | cytohesin 1 | -0.0212141 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0212093 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.0211989 |
| JUN | jun proto-oncogene | -0.0210271 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0209923 |
| PCED1B | PC-esterase domain containing 1B | -0.0208297 |
| RPL8 | ribosomal protein L8 | -0.0208152 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.020774 |
| SMYD3 | SET and MYND domain containing 3 | -0.0201633 |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | -0.0200949 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0200456 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.01996 |
| AOPEP | aminopeptidase O (putative) | -0.0199524 |
| VEGFA | vascular endothelial growth factor A | -0.0199387 |
