| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berbamine (dihydrochloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLEC | plectin | 0.177857 |
| FLNB | filamin B, beta | 0.16506 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.136674 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.122231 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.106867 |
| ITGA6 | integrin, alpha 6 | 0.0816758 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0786872 |
| AHNAK | AHNAK nucleoprotein | 0.0741511 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.070292 |
| EFNA5 | ephrin-A5 | 0.057921 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0548874 |
| SMAD3 | SMAD family member 3 | 0.0546897 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0543901 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0531209 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0513881 |
| EGFR | epidermal growth factor receptor | 0.0489956 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0471942 |
| NDRG1 | N-myc downstream regulated 1 | 0.0469509 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0451375 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0430425 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0413799 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0403006 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0388175 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0382922 |
| SLMAP | sarcolemma associated protein | 0.0365682 |
| FAM107B | family with sequence similarity 107, member B | 0.0360316 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0352127 |
| XPO1 | exportin 1 | 0.0348621 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0341985 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0336593 |
| HPCAL1 | hippocalcin-like 1 | 0.0334947 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0332331 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0329299 |
| ANLN | anillin, actin binding protein | 0.0324591 |
| OGA | O-GlcNAcase | 0.0324075 |
| ARRDC3 | arrestin domain containing 3 | 0.0321044 |
| FAM13A | family with sequence similarity 13, member A | 0.0319257 |
| STK39 | serine threonine kinase 39 | 0.0315645 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.0314055 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0308901 |
| DSPP | dentin sialophosphoprotein | 0.030436 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.029268 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0292557 |
| EZR | ezrin | 0.0291804 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0288263 |
| STAG2 | stromal antigen 2 | 0.0268619 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0267937 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.02672 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0265888 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0262466 |
| CCNY | cyclin Y | 0.0258113 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0255186 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0255098 |
| MED13L | mediator complex subunit 13-like | 0.0254134 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0252959 |
| TSC22D2 | TSC22 domain family, member 2 | 0.024455 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0243845 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0242267 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.024122 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0240616 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0239025 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0237945 |
| CTBP2 | C-terminal binding protein 2 | 0.0231195 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0230691 |
| MYOF | myoferlin | 0.0229513 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0228545 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0226006 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0223603 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0222446 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.021399 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0212422 |
| AFDN | afadin, adherens junction formation factor | 0.0211947 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0210767 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0210172 |
| TOP1 | topoisomerase (DNA) I | 0.020829 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.020819 |
| ANXA2 | annexin A2 | 0.0206561 |
| UBE2I | ubiquitin-conjugating enzyme E2I | 0.0206059 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.020535 |
| CAPRIN2 | caprin family member 2 | 0.0205056 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0203428 |
| EMP1 | epithelial membrane protein 1 | 0.0202956 |
| USP3 | ubiquitin specific peptidase 3 | 0.0202621 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0202519 |
| NEK7 | NIMA-related kinase 7 | 0.0201338 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0199554 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0199245 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0195799 |
| SLTM | SAFB-like, transcription modulator | 0.0195366 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0195282 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0194709 |
| SLK | STE20-like kinase | 0.0192483 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0192184 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0191949 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.019157 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0187923 |
| HMGB2 | high mobility group box 2 | 0.0187373 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0187216 |
| FOXO3 | forkhead box O3 | 0.0186912 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0186178 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.237804 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.141551 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.141383 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.130347 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.116921 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.107486 |
| KLK10 | kallikrein-related peptidase 10 | -0.101058 |
| FTL | ferritin, light polypeptide | -0.0915692 |
| EGR1 | early growth response 1 | -0.0841373 |
| B2M | beta-2-microglobulin | -0.0818393 |
| TXNIP | thioredoxin interacting protein | -0.0765246 |
| HMGA1 | high mobility group AT-hook 1 | -0.0725544 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0718491 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.070656 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0701762 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0590674 |
| FBXO11 | F-box protein 11 | -0.0583935 |
| POTEF | POTE ankyrin domain family, member F | -0.0579967 |
| CCNL1 | cyclin L1 | -0.0577785 |
| RPS21 | ribosomal protein S21 | -0.057694 |
| PARD3 | par-3 family cell polarity regulator | -0.056452 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0555691 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0536538 |
| RPL37A | ribosomal protein L37a | -0.0513122 |
| LAMC2 | laminin, gamma 2 | -0.0504754 |
| S100A11 | S100 calcium binding protein A11 | -0.050349 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0491501 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.048209 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0475914 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0464398 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0461101 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0434198 |
| RPL31 | ribosomal protein L31 | -0.0433315 |
| MXD1 | MAX dimerization protein 1 | -0.0423322 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.041684 |
| RPLP2 | ribosomal protein, large, P2 | -0.0416715 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0413788 |
| RPS13 | ribosomal protein S13 | -0.0412958 |
| HDAC9 | histone deacetylase 9 | -0.0393035 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0390599 |
| RTN4 | reticulon 4 | -0.0386363 |
| TJP1 | tight junction protein 1 | -0.0379085 |
| MT2A | metallothionein 2A | -0.0372983 |
| VMP1 | vacuole membrane protein 1 | -0.0367468 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0367022 |
| SNX9 | sorting nexin 9 | -0.0366814 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0365728 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0361031 |
| RPS3 | ribosomal protein S3 | -0.0356375 |
| LAMA4 | laminin, alpha 4 | -0.0354012 |
| AK1 | adenylate kinase 1 | -0.035387 |
| RPS23 | ribosomal protein S23 | -0.034591 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0344736 |
| FOSL1 | FOS-like antigen 1 | -0.0342407 |
| COG5 | component of oligomeric golgi complex 5 | -0.0334394 |
| ARF4 | ADP-ribosylation factor 4 | -0.0333812 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0332728 |
| RBM25 | RNA binding motif protein 25 | -0.0331633 |
| MIDN | midnolin | -0.03302 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0329693 |
| RPL23 | ribosomal protein L23 | -0.0329505 |
| RPL35A | ribosomal protein L35a | -0.0328311 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0319838 |
| GOLGB1 | golgin B1 | -0.0317583 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0312697 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0306127 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0301386 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0300633 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0299808 |
| RPL8 | ribosomal protein L8 | -0.0297125 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0296562 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0295497 |
| SDC4 | syndecan 4 | -0.0293458 |
| DENND2C | DENN/MADD domain containing 2C | -0.0292867 |
| VEGFA | vascular endothelial growth factor A | -0.0292674 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0291172 |
| PFN1 | profilin 1 | -0.0291092 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0290809 |
| DIAPH1 | diaphanous-related formin 1 | -0.0290147 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0289888 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0286028 |
| SP100 | SP100 nuclear antigen | -0.0285728 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | -0.0283187 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0281693 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.028041 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0279107 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0278685 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0276354 |
| RPL28 | ribosomal protein L28 | -0.0275949 |
| OSMR | oncostatin M receptor | -0.0272482 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0270472 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0269722 |
| RPL36 | ribosomal protein L36 | -0.0268694 |
| RPS27A | ribosomal protein S27a | -0.0268249 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0268093 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0268066 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0267549 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.02671 |
| SEM1 | SEM1 26S proteasome subunit | -0.0263732 |
| RPL9 | ribosomal protein L9 | -0.0258836 |