| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berbamine (dihydrochloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.149781 |
| CEP250 | centrosomal protein 250kDa | 0.11324 |
| NDRG1 | N-myc downstream regulated 1 | 0.0805792 |
| PLEC | plectin | 0.0747726 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0626036 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0581234 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0432419 |
| CLTC | clathrin, heavy chain (Hc) | 0.0417608 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0358417 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0348149 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0347279 |
| CCNY | cyclin Y | 0.0345639 |
| DTNA | dystrobrevin, alpha | 0.034384 |
| TMEM165 | transmembrane protein 165 | 0.0340409 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.033054 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0318682 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0303926 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0299693 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0298194 |
| FASN | fatty acid synthase | 0.0297334 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0296735 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0292272 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0288852 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0286266 |
| FAM13A | family with sequence similarity 13, member A | 0.0279738 |
| TMEM123 | transmembrane protein 123 | 0.0278894 |
| MYO10 | myosin X | 0.0268575 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0264337 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.025784 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0254138 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0253758 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0253501 |
| PLEKHG4B | pleckstrin homology domain containing, family G (with RhoGef domain) member 4B | 0.0253232 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0252859 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0250242 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0241822 |
| SET | SET nuclear proto-oncogene | 0.024031 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0238538 |
| ZNF292 | zinc finger protein 292 | 0.0237814 |
| KRT7 | keratin 7, type II | 0.0237236 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0234853 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0231362 |
| TPD52 | tumor protein D52 | 0.0229468 |
| FLNA | filamin A, alpha | 0.0227313 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0226713 |
| YEATS2 | YEATS domain containing 2 | 0.0224479 |
| MYOF | myoferlin | 0.0223295 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0214741 |
| EGFR | epidermal growth factor receptor | 0.0213353 |
| VIPR2 | vasoactive intestinal peptide receptor 2 | 0.0211876 |
| PRELID2 | PRELI domain containing 2 | 0.0211195 |
| TPM3 | tropomyosin 3 | 0.0210573 |
| DENND5A | DENN/MADD domain containing 5A | 0.0208571 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0208562 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0207233 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0202983 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0201865 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0200705 |
| HELZ | helicase with zinc finger | 0.0199793 |
| FAM219A | family with sequence similarity 219, member A | 0.0192032 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0190234 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.018811 |
| LASP1 | LIM and SH3 protein 1 | 0.0187925 |
| PCBP2 | poly(rC) binding protein 2 | 0.0187684 |
| RCOR1 | REST corepressor 1 | 0.0183959 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0183932 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0182843 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0182802 |
| DENND1A | DENN/MADD domain containing 1A | 0.01815 |
| USO1 | USO1 vesicle transport factor | 0.0180537 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0179646 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0178218 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0178073 |
| FLNB | filamin B, beta | 0.0178055 |
| LRRC59 | leucine rich repeat containing 59 | 0.0177423 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0176562 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0175552 |
| RPL3 | ribosomal protein L3 | 0.0174607 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0173483 |
| ORMDL3 | ORMDL sphingolipid biosynthesis regulator 3 | 0.0173107 |
| FOXO3 | forkhead box O3 | 0.0171103 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0170317 |
| COBL | cordon-bleu WH2 repeat protein | 0.0168929 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0168216 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.016696 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | 0.0166313 |
| MACROD1 | MACRO domain containing 1 | 0.01652 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0164066 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0163465 |
| DSTN | destrin (actin depolymerizing factor) | 0.0162323 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0162292 |
| RTN3 | reticulon 3 | 0.0161194 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0160756 |
| DSPP | dentin sialophosphoprotein | 0.0160335 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | 0.0160214 |
| ACTG1 | actin gamma 1 | 0.015996 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0159557 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0159106 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0154889 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0154844 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.228822 |
| RPL19 | ribosomal protein L19 | -0.202671 |
| MT2A | metallothionein 2A | -0.138099 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0910509 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0851741 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0837437 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0756523 |
| TMSB10 | thymosin beta 10 | -0.0726796 |
| S100A8 | S100 calcium binding protein A8 | -0.0689683 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0681821 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0659759 |
| PTMA | prothymosin, alpha | -0.0653481 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0622263 |
| EXT1 | exostosin glycosyltransferase 1 | -0.060256 |
| S100A9 | S100 calcium binding protein A9 | -0.0586186 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0576526 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0542627 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0496458 |
| TC2N | tandem C2 domains, nuclear | -0.0483212 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0479902 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0460138 |
| B2M | beta-2-microglobulin | -0.0446544 |
| RPS19 | ribosomal protein S19 | -0.0446231 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0442341 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0405179 |
| RPL12 | ribosomal protein L12 | -0.0392053 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0384498 |
| TXNRD1 | thioredoxin reductase 1 | -0.0383246 |
| S100A7 | S100 calcium binding protein A7 | -0.0375058 |
| RPLP1 | ribosomal protein, large, P1 | -0.0366295 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0363056 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0361486 |
| MYL12B | myosin, light chain 12B, regulatory | -0.035024 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0348544 |
| CCNI | cyclin I | -0.0346137 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0343102 |
| ASPH | aspartate beta-hydroxylase | -0.0334137 |
| CDK12 | cyclin-dependent kinase 12 | -0.0330433 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0327682 |
| RPS29 | ribosomal protein S29 | -0.0319592 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.031397 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0311966 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0310748 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0307896 |
| KAZN | kazrin, periplakin interacting protein | -0.0305646 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0305487 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0297954 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0295972 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0294898 |
| MIEN1 | migration and invasion enhancer 1 | -0.0288869 |
| OSMR | oncostatin M receptor | -0.0286313 |
| SDC4 | syndecan 4 | -0.0280906 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0280077 |
| PFDN4 | prefoldin subunit 4 | -0.0279928 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.027783 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0274606 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0274051 |
| ZNF217 | zinc finger protein 217 | -0.0271903 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0270193 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0269785 |
| SGMS1 | sphingomyelin synthase 1 | -0.0269047 |
| RAB7A | RAB7A, member RAS oncogene family | -0.026806 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0262872 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0261698 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0260677 |
| AREG | amphiregulin | -0.0259449 |
| DUSP16 | dual specificity phosphatase 16 | -0.0258017 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0257377 |
| RPL8 | ribosomal protein L8 | -0.0245946 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0245839 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0245194 |
| RPL35A | ribosomal protein L35a | -0.0244844 |
| GSK3B | glycogen synthase kinase 3 beta | -0.024239 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0242219 |
| CCNL1 | cyclin L1 | -0.0241901 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0236572 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0236271 |
| RPLP0 | ribosomal protein, large, P0 | -0.0234453 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0233728 |
| RPL31 | ribosomal protein L31 | -0.0233056 |
| FTL | ferritin, light polypeptide | -0.0232003 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.023179 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.02309 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0229181 |
| RPS24 | ribosomal protein S24 | -0.0228929 |
| GNAS | GNAS complex locus | -0.0225029 |
| RPS6 | ribosomal protein S6 | -0.0224965 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0223002 |
| NRCAM | neuronal cell adhesion molecule | -0.0216303 |
| YPEL2 | yippee-like 2 (Drosophila) | -0.0215309 |
| RPL5 | ribosomal protein L5 | -0.0214997 |
| RPL35 | ribosomal protein L35 | -0.0213979 |
| SMYD3 | SET and MYND domain containing 3 | -0.0212336 |
| RPS13 | ribosomal protein S13 | -0.0211133 |
| WWOX | WW domain containing oxidoreductase | -0.0208739 |
| IER3 | immediate early response 3 | -0.0206886 |
| RPS8 | ribosomal protein S8 | -0.0204684 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0204295 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0203986 |
| KLF6 | Kruppel-like factor 6 | -0.0202141 |
