| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine (dihydrochloride)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.14206 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.100907 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0953219 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0903607 |
| PCBP2 | poly(rC) binding protein 2 | 0.0899502 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.075087 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0733017 |
| GOLGA4 | golgin A4 | 0.0725632 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0722432 |
| TPM3 | tropomyosin 3 | 0.0637595 |
| ZNF292 | zinc finger protein 292 | 0.061596 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0571175 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0568441 |
| KIF5B | kinesin family member 5B | 0.0562429 |
| TMF1 | TATA element modulatory factor 1 | 0.0555677 |
| VEGFA | vascular endothelial growth factor A | 0.0555535 |
| NUP58 | nucleoporin 58 | 0.0552176 |
| ENO1 | enolase 1, (alpha) | 0.0549739 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0547991 |
| FDPS | farnesyl diphosphate synthase | 0.0542556 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0538091 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0527781 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0526604 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.052648 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0523923 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0522711 |
| SET | SET nuclear proto-oncogene | 0.0520354 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0487608 |
| CENPF | centromere protein F, 350/400kDa | 0.0484692 |
| NDRG1 | N-myc downstream regulated 1 | 0.0483314 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0466807 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0462904 |
| RPS3 | ribosomal protein S3 | 0.0461932 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.045691 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0456163 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0451834 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0436109 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0432583 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0428551 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0427034 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0418864 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0418455 |
| NCKAP1 | NCK-associated protein 1 | 0.0417821 |
| RIOK3 | RIO kinase 3 | 0.0412457 |
| YBX1 | Y box binding protein 1 | 0.0409204 |
| MKI67 | marker of proliferation Ki-67 | 0.0408991 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0404478 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0403987 |
| KRT18 | keratin 18, type I | 0.0401434 |
| BBX | bobby sox homolog (Drosophila) | 0.0399178 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0389918 |
| RPS12 | ribosomal protein S12 | 0.0389124 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0388205 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0385132 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0383348 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0381123 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0379608 |
| RCOR1 | REST corepressor 1 | 0.0378911 |
| PCM1 | pericentriolar material 1 | 0.0377778 |
| DSPP | dentin sialophosphoprotein | 0.0375823 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0371673 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0370377 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0361435 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0360202 |
| RBM26 | RNA binding motif protein 26 | 0.0357896 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0356045 |
| SMAD4 | SMAD family member 4 | 0.0356028 |
| RNF145 | ring finger protein 145 | 0.0355997 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.035139 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0350138 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0348843 |
| SBF2 | SET binding factor 2 | 0.0347621 |
| TFG | TRK-fused gene | 0.0346352 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0342012 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0340146 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.033833 |
| RPL7 | ribosomal protein L7 | 0.0335478 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0335158 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0334029 |
| HMGA1 | high mobility group AT-hook 1 | 0.0333137 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0331891 |
| INSIG2 | insulin induced gene 2 | 0.0329321 |
| ZNF148 | zinc finger protein 148 | 0.0327517 |
| TPX2 | TPX2, microtubule-associated | 0.0326736 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0326134 |
| RPS2 | ribosomal protein S2 | 0.0325958 |
| ERBIN | erbb2 interacting protein | 0.032378 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0322818 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.032211 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0320805 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0318719 |
| OGA | O-GlcNAcase | 0.0316784 |
| HJURP | Holliday junction recognition protein | 0.0315527 |
| ANXA2 | annexin A2 | 0.0315497 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0314934 |
| BRD2 | bromodomain containing 2 | 0.031264 |
| MT2A | metallothionein 2A | 0.031208 |
| MED13 | mediator complex subunit 13 | 0.0310688 |
| OPTN | optineurin | 0.0308008 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0307974 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.169125 |
| AHNAK | AHNAK nucleoprotein | -0.159488 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.122925 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.114273 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0868207 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0866595 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0673354 |
| CCDC200 | coiled-coil domain containing 200 | -0.0670811 |
| VCL | vinculin | -0.0604985 |
| INTS6 | integrator complex subunit 6 | -0.0602863 |
| TPM4 | tropomyosin 4 | -0.0601283 |
| HDLBP | high density lipoprotein binding protein | -0.059606 |
| PLEC | plectin | -0.0555509 |
| FUS | FUS RNA binding protein | -0.0552665 |
| PTMA | prothymosin, alpha | -0.0539604 |
| FAT1 | FAT atypical cadherin 1 | -0.0507764 |
| SERINC5 | serine incorporator 5 | -0.0492249 |
| RRBP1 | ribosome binding protein 1 | -0.0488519 |
| WWOX | WW domain containing oxidoreductase | -0.0475463 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0445825 |
| ARF1 | ADP-ribosylation factor 1 | -0.0420625 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0413043 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0406351 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0404477 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.040002 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0390703 |
| RPL7A | ribosomal protein L7a | -0.0388892 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0382673 |
| ZFHX3 | zinc finger homeobox 3 | -0.0373722 |
| FHIT | fragile histidine triad | -0.0369762 |
| GPHN | gephyrin | -0.0365152 |
| HMGB1 | high mobility group box 1 | -0.0347459 |
| RPLP2 | ribosomal protein, large, P2 | -0.0347309 |
| RPS25 | ribosomal protein S25 | -0.03468 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0344877 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0343129 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0336224 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0329374 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0327444 |
| RPS24 | ribosomal protein S24 | -0.0321756 |
| LRRC23 | leucine rich repeat containing 23 | -0.0320545 |
| RPL36A | ribosomal protein L36a | -0.0320154 |
| VMP1 | vacuole membrane protein 1 | -0.0319445 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0318965 |
| RPLP1 | ribosomal protein, large, P1 | -0.0317871 |
| SUMF1 | sulfatase modifying factor 1 | -0.0312432 |
| CTTN | cortactin | -0.0310526 |
| SDC4 | syndecan 4 | -0.0309307 |
| UBB | ubiquitin B | -0.0307792 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0306254 |
| CCND1 | cyclin D1 | -0.0305903 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0302704 |
| HBP1 | HMG-box transcription factor 1 | -0.0301427 |
| H1-4 | H1.4 linker histone, cluster member | -0.0298827 |
| SQSTM1 | sequestosome 1 | -0.0295937 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.029363 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0293448 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0286965 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -0.0285628 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0284587 |
| RPL4 | ribosomal protein L4 | -0.0284427 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0282716 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0280231 |
| HLA-E | major histocompatibility complex, class I, E | -0.0277426 |
| CUX1 | cut-like homeobox 1 | -0.0277229 |
| RPL8 | ribosomal protein L8 | -0.026851 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0266612 |
| GOLGA3 | golgin A3 | -0.0264899 |
| KLF6 | Kruppel-like factor 6 | -0.0264888 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0264298 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0262974 |
| FRMD5 | FERM domain containing 5 | -0.0262005 |
| DIAPH2 | diaphanous-related formin 2 | -0.0257236 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0254796 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0253679 |
| MTAP | methylthioadenosine phosphorylase | -0.0252579 |
| EGR1 | early growth response 1 | -0.0252024 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.0252021 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.025064 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0248739 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0247451 |
| JUN | jun proto-oncogene | -0.0245948 |
| PISD | phosphatidylserine decarboxylase | -0.0244805 |
| EPCAM | epithelial cell adhesion molecule | -0.024439 |
| RPL6 | ribosomal protein L6 | -0.0244284 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0242543 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0239699 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0238919 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0237282 |
| MYO1E | myosin IE | -0.0236004 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0235293 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0234926 |
| OXSR1 | oxidative stress responsive 1 | -0.0234914 |
| MSI2 | musashi RNA-binding protein 2 | -0.0234863 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0232971 |
| CALU | calumenin | -0.0232226 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.023127 |
| RTN3 | reticulon 3 | -0.022945 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0225943 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0224929 |
