| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine (dihydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.183207 |
| FN1 | fibronectin 1 | 0.145204 |
| NDRG1 | N-myc downstream regulated 1 | 0.134894 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.104418 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0989014 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0987116 |
| IGF2 | insulin-like growth factor 2 | 0.0829467 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0817327 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0781828 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0739418 |
| NAV2 | neuron navigator 2 | 0.072006 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0717715 |
| VEGFA | vascular endothelial growth factor A | 0.069742 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0673595 |
| PCBP2 | poly(rC) binding protein 2 | 0.0650384 |
| ENO1 | enolase 1, (alpha) | 0.0642199 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0624315 |
| MSN | moesin | 0.0622072 |
| ANXA2 | annexin A2 | 0.0620286 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0598687 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0595791 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0580489 |
| FAM13A | family with sequence similarity 13, member A | 0.057193 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0549469 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0546589 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0544238 |
| FLNB | filamin B, beta | 0.0544028 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0536586 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0533711 |
| RTN4 | reticulon 4 | 0.0519333 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0502053 |
| CENPF | centromere protein F, 350/400kDa | 0.0501892 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0501717 |
| ADM | adrenomedullin | 0.0500485 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0500414 |
| RUNX1 | runt-related transcription factor 1 | 0.0489502 |
| HJURP | Holliday junction recognition protein | 0.0482557 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.047806 |
| ARRDC3 | arrestin domain containing 3 | 0.0476465 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0467111 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.046251 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.045571 |
| ZNF148 | zinc finger protein 148 | 0.0451153 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0437851 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0437142 |
| NUP58 | nucleoporin 58 | 0.0430645 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0426057 |
| SEPTIN9 | septin 9 | 0.0424983 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0419186 |
| RPS12 | ribosomal protein S12 | 0.0418956 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0412427 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.040572 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0405218 |
| YBX1 | Y box binding protein 1 | 0.0403682 |
| TPM3 | tropomyosin 3 | 0.040295 |
| PRELID2 | PRELI domain containing 2 | 0.0394182 |
| MT2A | metallothionein 2A | 0.0393805 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0391262 |
| ZNF292 | zinc finger protein 292 | 0.0387834 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0383827 |
| TNS1 | tensin 1 | 0.0380678 |
| SET | SET nuclear proto-oncogene | 0.0380488 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0375845 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0372372 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0368588 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0360673 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0357217 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0355084 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0351154 |
| RPL23 | ribosomal protein L23 | 0.0348137 |
| SP3 | Sp3 transcription factor | 0.0336869 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0334586 |
| MCL1 | myeloid cell leukemia 1 | 0.0334384 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0331227 |
| TFG | TRK-fused gene | 0.0330767 |
| ASPH | aspartate beta-hydroxylase | 0.0330362 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0330294 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0329167 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0326759 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0326706 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0323701 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.032344 |
| CUL3 | cullin 3 | 0.0322537 |
| RPS3 | ribosomal protein S3 | 0.0319513 |
| RPL11 | ribosomal protein L11 | 0.0317982 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0313949 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0312953 |
| INSIG1 | insulin induced gene 1 | 0.0312144 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0312065 |
| PTK2 | protein tyrosine kinase 2 | 0.0308863 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0301088 |
| RPS6 | ribosomal protein S6 | 0.0299998 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0294698 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0294085 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0294012 |
| ARF4 | ADP-ribosylation factor 4 | 0.0292437 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.029108 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0290647 |
| NGLY1 | N-glycanase 1 | 0.0288713 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.028791 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.459223 |
| HMGA2 | high mobility group AT-hook 2 | -0.162169 |
| CD44 | CD44 molecule (Indian blood group) | -0.117915 |
| EXT1 | exostosin glycosyltransferase 1 | -0.112148 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.107671 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0850884 |
| LOX | lysyl oxidase | -0.075347 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0745472 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.072657 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0622928 |
| PLEC | plectin | -0.0598728 |
| ACTG1 | actin gamma 1 | -0.0592389 |
| AHNAK | AHNAK nucleoprotein | -0.0546544 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0535337 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0526894 |
| VCL | vinculin | -0.051674 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0511754 |
| TNNC1 | troponin C type 1 (slow) | -0.0500612 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0493079 |
| EGR1 | early growth response 1 | -0.0451319 |
| GLIS3 | GLIS family zinc finger 3 | -0.0450015 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0439864 |
| COL5A1 | collagen, type V, alpha 1 | -0.0435642 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0400101 |
| LDHA | lactate dehydrogenase A | -0.0384363 |
| OSMR | oncostatin M receptor | -0.0369428 |
| CAVIN1 | caveolae associated protein 1 | -0.0338065 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0317842 |
| RAI14 | retinoic acid induced 14 | -0.0316264 |
| CCND1 | cyclin D1 | -0.0308685 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0303724 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0292617 |
| TMSB10 | thymosin beta 10 | -0.0288788 |
| TENM2 | teneurin transmembrane protein 2 | -0.0284319 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0273433 |
| COL1A1 | collagen, type I, alpha 1 | -0.0258522 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0252854 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0246614 |
| TAOK1 | TAO kinase 1 | -0.0244736 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0243178 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0239794 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0237896 |
| ARF1 | ADP-ribosylation factor 1 | -0.0235704 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0233523 |
| TPM1 | tropomyosin 1 (alpha) | -0.0230224 |
| INHBA | inhibin, beta A | -0.022834 |
| TNS3 | tensin 3 | -0.022632 |
| VMP1 | vacuole membrane protein 1 | -0.022623 |
| STC1 | stanniocalcin 1 | -0.0226162 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.022417 |
| MYO9A | myosin IXA | -0.0220424 |
| CCDC200 | coiled-coil domain containing 200 | -0.0213853 |
| IER3 | immediate early response 3 | -0.0210972 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0210323 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0199382 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0191819 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0187708 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0187684 |
| RPL6 | ribosomal protein L6 | -0.0183126 |
| S100A10 | S100 calcium binding protein A10 | -0.0180461 |
| RAB31 | RAB31, member RAS oncogene family | -0.0179572 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | -0.0179138 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0177595 |
| NABP1 | nucleic acid binding protein 1 | -0.0171418 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0170768 |
| PALLD | palladin, cytoskeletal associated protein | -0.0170527 |
| MORF4L2 | mortality factor 4 like 2 | -0.0169717 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0168696 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0166109 |
| SYNJ2 | synaptojanin 2 | -0.0165941 |
| RND3 | Rho family GTPase 3 | -0.0162342 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.01612 |
| CCNI | cyclin I | -0.0159651 |
| BPTF | bromodomain PHD finger transcription factor | -0.0158416 |
| CALU | calumenin | -0.0157213 |
| RRBP1 | ribosome binding protein 1 | -0.0156879 |
| PCNX4 | pecanex 4 | -0.0156706 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.015648 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0155368 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0154364 |
| FUS | FUS RNA binding protein | -0.0153625 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0153183 |
| TMEM263 | transmembrane protein 263 | -0.0152948 |
| UBB | ubiquitin B | -0.0151847 |
| SDC4 | syndecan 4 | -0.0150868 |
| TXNIP | thioredoxin interacting protein | -0.0150397 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0149457 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0149047 |
| IL11 | interleukin 11 | -0.0147402 |
| CLMP | CXADR-like membrane protein | -0.0147036 |
| SMYD3 | SET and MYND domain containing 3 | -0.0144112 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0142541 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0142346 |
| BSG | basigin (Ok blood group) | -0.0142237 |
| GOLGA3 | golgin A3 | -0.0140535 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0139819 |
| CANX | calnexin | -0.0137592 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0137578 |
| MORF4L1 | mortality factor 4 like 1 | -0.0137497 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0136915 |
