| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berbamine (dihydrochloride)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.383308 |
| FN1 | fibronectin 1 | 0.368664 |
| COL6A3 | collagen, type VI, alpha 3 | 0.168525 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.127094 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.111604 |
| NDRG1 | N-myc downstream regulated 1 | 0.104429 |
| ENO1 | enolase 1, (alpha) | 0.0891527 |
| SQLE | squalene epoxidase | 0.0806986 |
| VIM | vimentin | 0.0738955 |
| INSIG1 | insulin induced gene 1 | 0.0708098 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0602914 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0592844 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0550061 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0548551 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0491972 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.0470856 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0470614 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0419234 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0397699 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0393112 |
| EGR1 | early growth response 1 | 0.0390369 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0383552 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.038227 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0368079 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0365877 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0365406 |
| FDPS | farnesyl diphosphate synthase | 0.0359811 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0357432 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0352054 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0349655 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0347728 |
| ANXA2 | annexin A2 | 0.0344622 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.034271 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0328247 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.031725 |
| CALR | calreticulin | 0.031092 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.03053 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0304503 |
| CADM1 | cell adhesion molecule 1 | 0.0304384 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0300491 |
| NAV2 | neuron navigator 2 | 0.0293512 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0289076 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0285111 |
| YBX1 | Y box binding protein 1 | 0.0283733 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.0281309 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0278572 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0275401 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0269754 |
| RPL23 | ribosomal protein L23 | 0.0262237 |
| PKM | pyruvate kinase, muscle | 0.0257886 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0253291 |
| HDAC9 | histone deacetylase 9 | 0.0252216 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0251822 |
| LIPG | lipase, endothelial | 0.0243948 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0243617 |
| SOAT2 | sterol O-acyltransferase 2 | 0.0241674 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0241119 |
| CLIC4 | chloride intracellular channel 4 | 0.0238779 |
| SQSTM1 | sequestosome 1 | 0.0238371 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0237925 |
| GPC6 | glypican 6 | 0.0237063 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0234426 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0233891 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0230703 |
| PANK3 | pantothenate kinase 3 | 0.0230633 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0227811 |
| TFG | TRK-fused gene | 0.0226218 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.022395 |
| RND3 | Rho family GTPase 3 | 0.0223746 |
| AFF4 | AF4/FMR2 family, member 4 | 0.021561 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.0209888 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0209841 |
| RPLP0 | ribosomal protein, large, P0 | 0.0206631 |
| KAZN | kazrin, periplakin interacting protein | 0.0205758 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0204738 |
| FOSL1 | FOS-like antigen 1 | 0.0203958 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0201909 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0201275 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0199109 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0198664 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0197768 |
| HYOU1 | hypoxia up-regulated 1 | 0.0196875 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0196079 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0195444 |
| BBX | bobby sox homolog (Drosophila) | 0.0192658 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0190212 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0188472 |
| TMEM41B | transmembrane protein 41B | 0.0188445 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0180378 |
| CD109 | CD109 molecule | 0.0180357 |
| GPHN | gephyrin | 0.0180078 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0179033 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0178489 |
| KLF10 | Kruppel-like factor 10 | 0.0177574 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0175189 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0174754 |
| HLA-C | major histocompatibility complex, class I, C | 0.0174339 |
| PLEC | plectin | 0.0173414 |
| KLHL24 | kelch-like family member 24 | 0.017229 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0170673 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.174784 |
| COL1A1 | collagen, type I, alpha 1 | -0.161664 |
| EXT1 | exostosin glycosyltransferase 1 | -0.122968 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.110857 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.101951 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0828272 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0732155 |
| STC1 | stanniocalcin 1 | -0.0691378 |
| COL1A2 | collagen, type I, alpha 2 | -0.0673538 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0668591 |
| CD44 | CD44 molecule (Indian blood group) | -0.0592161 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0590685 |
| HMGA2 | high mobility group AT-hook 2 | -0.0477932 |
| MT1X | metallothionein 1X | -0.0463106 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0455529 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.044251 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0380679 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0376202 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0366088 |
| HLA-B | major histocompatibility complex, class I, B | -0.0361471 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0358255 |
| PDE10A | phosphodiesterase 10A | -0.0347844 |
| DST | dystonin | -0.0344021 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0336191 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0335748 |
| GLIS3 | GLIS family zinc finger 3 | -0.0332967 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0328637 |
| LOXL2 | lysyl oxidase-like 2 | -0.0321558 |
| CALD1 | caldesmon 1 | -0.0321307 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0320769 |
| RRBP1 | ribosome binding protein 1 | -0.0318273 |
| ECE1 | endothelin converting enzyme 1 | -0.0310608 |
| LDHA | lactate dehydrogenase A | -0.0310537 |
| LOX | lysyl oxidase | -0.0295088 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0291569 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0288785 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0286056 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.028594 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0284379 |
| MTSS1 | metastasis suppressor 1 | -0.0284091 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0283337 |
| ASPH | aspartate beta-hydroxylase | -0.0281717 |
| CAVIN1 | caveolae associated protein 1 | -0.0281141 |
| SDC2 | syndecan 2 | -0.0276181 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0273248 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0267877 |
| COL5A1 | collagen, type V, alpha 1 | -0.0267369 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0262002 |
| HAS2 | hyaluronan synthase 2 | -0.0260028 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0250198 |
| SMAD3 | SMAD family member 3 | -0.0247955 |
| RBM39 | RNA binding motif protein 39 | -0.0247187 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0245708 |
| RPS2 | ribosomal protein S2 | -0.0244834 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0244758 |
| NKTR | natural killer cell triggering receptor | -0.0243125 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0234993 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0234209 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0233574 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0232126 |
| TPM1 | tropomyosin 1 (alpha) | -0.0228153 |
| FRMD4A | FERM domain containing 4A | -0.0227992 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0225571 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0225181 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0224122 |
| VCAN | versican | -0.0221996 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0221707 |
| SLC22A23 | solute carrier family 22, member 23 | -0.0219192 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0218325 |
| PTMA | prothymosin, alpha | -0.0218135 |
| PTK2 | protein tyrosine kinase 2 | -0.0218112 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.021069 |
| RPL38 | ribosomal protein L38 | -0.0209807 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0208913 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0208774 |
| MYO9B | myosin IXB | -0.020768 |
| ATP13A3 | ATPase type 13A3 | -0.0203074 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0201043 |
| IFNGR1 | interferon gamma receptor 1 | -0.0199739 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0198246 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0195314 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0195243 |
| SVIL | supervillin | -0.0194844 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0191511 |
| MAP4 | microtubule-associated protein 4 | -0.0189581 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.018928 |
| VEGFA | vascular endothelial growth factor A | -0.0188737 |
| EBF1 | early B-cell factor 1 | -0.0188216 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0187185 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0186151 |
| ANKRD36 | ankyrin repeat domain 36 | -0.0185729 |
| JAG1 | jagged 1 | -0.0185294 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0184398 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0182596 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0180631 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0176443 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0175417 |
| PTN | pleiotrophin | -0.0175377 |
| RPL32 | ribosomal protein L32 | -0.0174185 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0174096 |
