| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berbamine (dihydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0920587 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0302946 |
| VEGFA | vascular endothelial growth factor A | 0.0298112 |
| FAM13A | family with sequence similarity 13, member A | 0.0291201 |
| TNS1 | tensin 1 | 0.0179134 |
| ARF4 | ADP-ribosylation factor 4 | 0.017166 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0132527 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0130661 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0129172 |
| DSPP | dentin sialophosphoprotein | 0.012544 |
| UGT1A8 | UDP glucuronosyltransferase 1 family, polypeptide A8 | 0.0112038 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0104499 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.00988753 |
| JUP | junction plakoglobin | 0.0097171 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00946004 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00930952 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.00913818 |
| GRAMD1B | GRAM domain containing 1B | 0.00903985 |
| VIM | vimentin | 0.00898881 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00889514 |
| FAM162A | family with sequence similarity 162, member A | 0.00888677 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.00886706 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00882082 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.00848941 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.00845781 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00835846 |
| MT2A | metallothionein 2A | 0.00835546 |
| CCNL1 | cyclin L1 | 0.00830498 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.00828337 |
| NUCB2 | nucleobindin 2 | 0.00813233 |
| MKRN1 | makorin ring finger protein 1 | 0.0081187 |
| ABHD2 | abhydrolase domain containing 2 | 0.0080421 |
| GOLGA2 | golgin A2 | 0.00788932 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00774208 |
| OPTN | optineurin | 0.0076607 |
| FOSL1 | FOS-like antigen 1 | 0.00760953 |
| CA9 | carbonic anhydrase IX | 0.00760953 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.00747073 |
| TRIM31 | tripartite motif containing 31 | 0.00745696 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.00738268 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.00731208 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00705704 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.00698712 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00696854 |
| EPS8L1 | EPS8-like 1 | 0.00685442 |
| CDH13 | cadherin 13 | 0.00680487 |
| ZNF395 | zinc finger protein 395 | 0.00676273 |
| CCNY | cyclin Y | 0.0067097 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.00669706 |
| GRB10 | growth factor receptor-bound protein 10 | 0.00660077 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00659724 |
| PER2 | period circadian clock 2 | 0.00644966 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00640637 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.00626285 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.00623374 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.00621804 |
| CPAP | centrosome assembly and centriole elongation protein | 0.00617827 |
| RAB6A | RAB6A, member RAS oncogene family | 0.00617121 |
| MYRF | myelin regulatory factor | 0.00611469 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.00608819 |
| HGD | homogentisate 1,2-dioxygenase | 0.00598153 |
| RPL21 | ribosomal protein L21 | 0.00592359 |
| KIF16B | kinesin family member 16B | 0.0058811 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.00583562 |
| PTGR1 | prostaglandin reductase 1 | 0.00579104 |
| TCP11L2 | t-complex 11, testis-specific-like 2 | 0.00566184 |
| ANXA1 | annexin A1 | 0.005618 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0056157 |
| TOGARAM1 | TOG array regulator of axonemal microtubules 1 | 0.00555702 |
| USP6NL | USP6 N-terminal like | 0.00552389 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00541717 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.00540789 |
| HOXB6 | homeobox B6 | 0.00540523 |
| EFNA1 | ephrin-A1 | 0.00539444 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | 0.00533768 |
| TSC22D4 | TSC22 domain family, member 4 | 0.00523884 |
| CDK11A | cyclin-dependent kinase 11A | 0.00523559 |
| PDGFC | platelet derived growth factor C | 0.00522955 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.00522908 |
| TMEM260 | transmembrane protein 260 | 0.00522041 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.00520713 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.00518838 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.00515008 |
| TJP3 | tight junction protein 3 | 0.00514486 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00514087 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.00511662 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.00509764 |
| RAB5B | RAB5B, member RAS oncogene family | 0.00509481 |
| ASS1 | argininosuccinate synthase 1 | 0.00505372 |
| UGT1A9 | UDP glucuronosyltransferase 1 family, polypeptide A9 | 0.00504291 |
| MBD6 | methyl-CpG binding domain protein 6 | 0.00502938 |
| CGN | cingulin | 0.00502407 |
| NXPH4 | neurexophilin 4 | 0.00501986 |
| MSN | moesin | 0.00501781 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.00500315 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | 0.00497363 |
| ANXA3 | annexin A3 | 0.00496234 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.00495597 |
| MMP12 | matrix metallopeptidase 12 | 0.00493455 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00492087 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.190029 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.159772 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.134418 |
| EXT1 | exostosin glycosyltransferase 1 | -0.122521 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.119018 |
| PTMA | prothymosin, alpha | -0.11431 |
| UBC | ubiquitin C | -0.111572 |
| RPL23 | ribosomal protein L23 | -0.0959253 |
| AHNAK | AHNAK nucleoprotein | -0.0923086 |
| TMSB10 | thymosin beta 10 | -0.0919403 |
| RPS27A | ribosomal protein S27a | -0.0801421 |
| SMAD3 | SMAD family member 3 | -0.0797767 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0761378 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0731049 |
| KRT8 | keratin 8, type II | -0.0729748 |
| ACTG1 | actin gamma 1 | -0.0721867 |
| RPLP1 | ribosomal protein, large, P1 | -0.071904 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0714446 |
| ACTN4 | actinin, alpha 4 | -0.0693336 |
| RPS8 | ribosomal protein S8 | -0.0681197 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0673083 |
| TJP1 | tight junction protein 1 | -0.0646379 |
| FTL | ferritin, light polypeptide | -0.0641284 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0622939 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0618324 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.06174 |
| RPS6 | ribosomal protein S6 | -0.0607726 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0593688 |
| RPS24 | ribosomal protein S24 | -0.0584486 |
| S100A10 | S100 calcium binding protein A10 | -0.0576194 |
| LAMA4 | laminin, alpha 4 | -0.0558054 |
| RPLP2 | ribosomal protein, large, P2 | -0.0537957 |
| RPS19 | ribosomal protein S19 | -0.0536592 |
| RPS11 | ribosomal protein S11 | -0.0520219 |
| RPS5 | ribosomal protein S5 | -0.0514459 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0504124 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0498341 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0494933 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0491993 |
| RPS3 | ribosomal protein S3 | -0.0484738 |
| RPL28 | ribosomal protein L28 | -0.0479154 |
| MYO1E | myosin IE | -0.0478689 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0474891 |
| VMP1 | vacuole membrane protein 1 | -0.0468652 |
| RPS16 | ribosomal protein S16 | -0.0467302 |
| CANX | calnexin | -0.0464789 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0456395 |
| PTK2 | protein tyrosine kinase 2 | -0.0456325 |
| JUN | jun proto-oncogene | -0.0453136 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0435961 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0435384 |
| ENO1 | enolase 1, (alpha) | -0.0434735 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0429152 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0425317 |
| RPS21 | ribosomal protein S21 | -0.0421017 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0419813 |
| RPLP0 | ribosomal protein, large, P0 | -0.0419517 |
| RPS25 | ribosomal protein S25 | -0.041872 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0416349 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0415038 |
| RPL34 | ribosomal protein L34 | -0.0411882 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0408661 |
| RPS13 | ribosomal protein S13 | -0.0408109 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0402603 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0395104 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0394959 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0389067 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0387852 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0383986 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0381919 |
| RPS23 | ribosomal protein S23 | -0.0381759 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0379883 |
| S100A6 | S100 calcium binding protein A6 | -0.0377536 |
| RPL12 | ribosomal protein L12 | -0.0377365 |
| VCL | vinculin | -0.037677 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.03756 |
| RPL8 | ribosomal protein L8 | -0.0368391 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0366221 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0365933 |
| PCBP2 | poly(rC) binding protein 2 | -0.0364942 |
| RPL11 | ribosomal protein L11 | -0.0364539 |
| FNDC3B | fibronectin type III domain containing 3B | -0.036392 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0362531 |
| TRIB1 | tribbles pseudokinase 1 | -0.0359296 |
| OGA | O-GlcNAcase | -0.035353 |
| LMO7 | LIM domain 7 | -0.0352752 |
| ASPH | aspartate beta-hydroxylase | -0.0352733 |
| RPL31 | ribosomal protein L31 | -0.0351812 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0348696 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0345016 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0342632 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0341217 |
| TOP1 | topoisomerase (DNA) I | -0.0339025 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0332364 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0331861 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0330249 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0327783 |
| NTN4 | netrin 4 | -0.0327731 |
| RPL35A | ribosomal protein L35a | -0.0327514 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0326791 |